Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Steffen K Meurer"'
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274219 (2022)
Misidentification, cross-contamination and genetic drift of continuous animal cell lines are persistent problems in biomedical research, leading to erroneous results and inconsistent or invalidated studies. The establishment of immortalized hepatic s
Externí odkaz:
https://doaj.org/article/11f639816e834348a4b2db08b85141e3
Autor:
Steffen K Meurer, Melanie Neß, Sabine Weiskirchen, Philipp Kim, Carmen G Tag, Marlies Kauffmann, Michael Huber, Ralf Weiskirchen
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158104 (2016)
Mast cells (MCs) are a versatile cell type playing key roles in tissue morphogenesis and host defence against bacteria and parasites. Furthermore, they can enhance immunological danger signals and are implicated in inflammatory disorders like fibrosi
Externí odkaz:
https://doaj.org/article/00efb8f053f74492b88f83ac72130ff0
Autor:
Paola Berenice Mass-Sanchez, Marinela Krizanac, Paula Štancl, Marvin Leopold, Kathrin M. Engel, Eva Miriam Buhl, Josef van Helden, Nikolaus Gassler, Jürgen Schiller, Rosa Karlić, Diana Möckel, Twan Lammers, Steffen K. Meurer, Ralf Weiskirchen, Anastasia Asimakopoulos
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The molecular mechanisms underlying the transition from nonalcoholic fatty liver disease (NAFLD) to hepatocellular carcinoma (HCC) are incompletely understood. During the development of NAFLD, Perilipin 5 (PLIN5) can regulate lipid metabolis
Externí odkaz:
https://doaj.org/article/2fdd9001212f423bba51c0fecc09dd17
Autor:
Ralf Weiskirchen, Jörg Weimer, Steffen K Meurer, Anja Kron, Barbara Seipel, Inga Vater, Norbert Arnold, Reiner Siebert, Lieming Xu, Scott L Friedman, Carsten Bergmann
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75692 (2013)
The human hepatic cell line LX-2 has been described as tool to study mechanisms of hepatic fibrogenesis and the testing of antifibrotic compounds. It was originally generated by immortalisation with the Simian Vacuolating Virus 40 (SV40) transforming
Externí odkaz:
https://doaj.org/article/13fb714e156d4946b886667d8d892c0f
Autor:
Steffen K Meurer, Muhammad Alsamman, Hacer Sahin, Hermann E Wasmuth, Tatiana Kisseleva, David A Brenner, Christian Trautwein, Ralf Weiskirchen, David Scholten
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56116 (2013)
Hepatic stellate cells (HSCs) play a major role in the pathogenesis of liver fibrosis. Working on primary HSCs requires difficult isolation procedures; therefore we have generated and here characterize a mouse hepatic stellate cell line expressing GF
Externí odkaz:
https://doaj.org/article/f98442e78520473b8393663f3ef09037
Autor:
Sandro Capellmann, Roland Sonntag, Herdit Schüler, Steffen K. Meurer, Lin Gan, Marlies Kauffmann, Katharina Horn, Hiltrud Königs-Werner, Ralf Weiskirchen, Christian Liedtke, Michael Huber
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Mast cells (MCs) are immune cells of the myeloid lineage distributed in tissues throughout the body. Phenotypically, they are a heterogeneous group characterized by different protease repertoires stored in secretory granules and differential presence
Externí odkaz:
https://doaj.org/article/1744234839ac4319bba1af4354d2a61b
Autor:
Indrajit Nanda, Claus Steinlein, Thomas Haaf, Eva M. Buhl, Domink G. Grimm, Scott L. Friedman, Steffen K. Meurer, Sarah K. Schröder, Ralf Weiskirchen
Publikováno v:
Cells, Vol 11, Iss 11, p 1783 (2022)
Immortalized hepatic stellate cells (HSCs) established from mouse, rat, and humans are valuable in vitro models for the biomedical investigation of liver biology. These cell lines are homogenous, thereby providing consistent and reproducible results.
Externí odkaz:
https://doaj.org/article/71a3339035434fa089fbb814bdee7e41
Autor:
Elisabeth Letellier, Serge Haan, Ralf Weiskirchen, Nikolaus Zügel, Sonia Frasquilho, Laurent Antunes, Aurélien Ginolhac, Paul Felten, Komal Qureshi-Baig, Steffen K. Meurer, Martine Schmitz, Fabien Rodriguez, Pit Ullmann
Lentiviral transduction of miR-371~373 cluster restores miR-371~373 expression in different SCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1481f6c355d5fced708214bb0929e66f
https://doi.org/10.1158/0008-5472.22420314.v1
https://doi.org/10.1158/0008-5472.22420314.v1
Autor:
Elisabeth Letellier, Serge Haan, Ralf Weiskirchen, Nikolaus Zügel, Sonia Frasquilho, Laurent Antunes, Aurélien Ginolhac, Paul Felten, Komal Qureshi-Baig, Steffen K. Meurer, Martine Schmitz, Fabien Rodriguez, Pit Ullmann
Antibodies, primers, and lentiviral particles (S1); in vivo tumorigenicity for SW480 vs. SW620 (S2); top 20 differentially expressed miRNAs (S3); peritoneal cancer index scores (S4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c12c93b1f5daa20e32d1264d3b48af2
https://doi.org/10.1158/0008-5472.22420299.v1
https://doi.org/10.1158/0008-5472.22420299.v1
Autor:
Elisabeth Letellier, Serge Haan, Ralf Weiskirchen, Nikolaus Zügel, Sonia Frasquilho, Laurent Antunes, Aurélien Ginolhac, Paul Felten, Komal Qureshi-Baig, Steffen K. Meurer, Martine Schmitz, Fabien Rodriguez, Pit Ullmann
The vast majority of colorectal cancer–related deaths can be attributed to metastatic spreading of the disease. Therefore, deciphering molecular mechanisms of metastatic dissemination is a key prerequisite to improve future treatment options. With
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff87abaef91c92d594957ae7e6198ed
https://doi.org/10.1158/0008-5472.c.6510615
https://doi.org/10.1158/0008-5472.c.6510615