The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms

Autor: Tang Cam Phung Pham, Steffen Henning Raun, Essi Havula, Carlos Henriquez-Olguín, Diana Rubalcava-Gracia, Emma Frank, Andreas Mæchel Fritzen, Paulo R. Jannig, Nicoline Resen Andersen, Rikke Kruse, Mona Sadek Ali, Andrea Irazoki, Jens Frey Halling, Stine Ringholm, Elise J. Needham, Solvejg Hansen, Anders Krogh Lemminger, Peter Schjerling, Maria Houborg Petersen, Martin Eisemann de Almeida, Thomas Elbenhardt Jensen, Bente Kiens, Morten Hostrup, Steen Larsen, Niels Ørtenblad, Kurt Højlund, Michael Kjær, Jorge L. Ruas, Aleksandra Trifunovic, Jørgen Frank Pind Wojtaszewski, Joachim Nielsen, Klaus Qvortrup, Henriette Pilegaard, Erik Arne Richter, Lykke Sylow

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)

Abstract Decline in mitochondrial function is linked to decreased muscle mass and strength in conditions like sarcopenia and type 2 diabetes. Despite therapeutic opportunities, there is limited and equivocal data regarding molecular cues controlling

Externí odkaz: https://doaj.org/article/ed2fae7f50be41fcb8c22822e7b50e9c

The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action

Autor: Møller, Lisbeth L V, Ali, Mona Sadek, Davey, Jonathan, Raun, Steffen Henning, Andersen, Nicoline Resen, Long, Jonathan Z, Qian, Hongwei, Jeppesen, Jacob Fuglsbjerg, Henriquez-Olguin, Carlos, Frank, Emma, Jensen, Thomas Elbenhardt, Højlund, Kurt, Wojtaszewski, Jørgen, Nielsen, Joachim, Chiu, Tim T, Jedrychowski, Mark P, Gregorevic, Paul, Klip, Amira, Richter, Erik A., Sylow, Lykke

Publikováno v: Møller, L L V, Ali, M S, Davey, J, Raun, S H, Andersen, N R, Long, J Z, Qian, H, Jeppesen, J F, Henriquez-Olguin, C, Frank, E, Jensen, T E, Højlund, K, Wojtaszewski, J, Nielsen, J, Chiu, T T, Jedrychowski, M P, Gregorevic, P, Klip, A, Richter, E A & Sylow, L 2023, ' The Rho guanine dissociation inhibitor α inhibits skeletal muscle Rac1 activity and insulin action ', Proceedings of the National Academy of Sciences of the United States of America, vol. 120, no. 27, e2211041120 . https://doi.org/10.1073/pnas.2211041120

The molecular events governing skeletal muscle glucose uptake have pharmacological potential for managing insulin resistance in conditions such as obesity, diabetes, and cancer. With no current pharmacological treatments to target skeletal muscle ins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::b0df2f79cd63b91b1d29e4177681df50
https://curis.ku.dk/ws/files/358723573/Moller_et_al_PNAS_2023_Vol_120_27_e2211041120.pdf

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Transesophageal echocardiography in swine: evaluation of left and right ventricular structure, function and myocardial work.

Autor: Billig, Sebastian, Zayat, Rashad, Ebeling, Andreas, Steffen, Henning, Nix, Christoph, Hatam, Nima, Schnöring, Heike, Derwall, Matthias

Publikováno v: International Journal of Cardiovascular Imaging; Mar2021, Vol. 37 Issue 3, p835-846, 12p

Pattern-based control-code synthesis

Autor: Jens Otto, Oliver Niggemann, Steffen Henning

Publikováno v: INDIN

Manufacturing plants become more complex as the desire for modern individual products increases. Programming such plants is a challenging task that consumes a lot of time. This paper proposes a new control-code synthesis algorithm, which aids the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0786df7e9735b19100126037f9d4a81
https://doi.org/10.1109/indin.2016.7819330