Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Steffen Frese"'
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Objective Topoisomerase I (topo I) is a highly conserved enzyme which is known to reduce torsional stress at double-stranded (ds) DNA. Torsional stress induced by supercoiling of dsDNA requires either very long dsDNA existing in genomic DNA
Externí odkaz:
https://doaj.org/article/dedf3310eec54890b269618e287ba7d7
Autor:
Philipp Genseke, Christoph Ferdinand Wielenberg, Jens Schreiber, Eva Luecke, Steffen Frese, Thorsten Walles, Michael Christoph Kreissl
Publikováno v:
Diagnostics, Vol 13, Iss 7, p 1263 (2023)
Purpose: Pre-operative assessment of thoracic lymphonodal (LN) involvement in patients with lung cancer (LC) is crucial when choosing the treatment modality. Visual assessment of F-18-FDG-PET/CT (PET/CT) is well established, however, there is still a
Externí odkaz:
https://doaj.org/article/dbe997d0f11946ea9c88bf58822e0054
Autor:
Sabrina Grasse, Matthias Lienhard, Steffen Frese, Martin Kerick, Anne Steinbach, Christina Grimm, Michelle Hussong, Jana Rolff, Michael Becker, Felix Dreher, Uwe Schirmer, Stefan Boerno, Anna Ramisch, Gunda Leschber, Bernd Timmermann, Christian Grohé, Heike Lüders, Martin Vingron, Iduna Fichtner, Sebastian Klein, Margarete Odenthal, Reinhard Büttner, Hans Lehrach, Holger Sültmann, Ralf Herwig, Michal R. Schweiger
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide and is primarily treated with radiation, surgery, and platinum-based drugs like cisplatin and carboplatin. The major challenge in the t
Externí odkaz:
https://doaj.org/article/84b7234bcdf146459a94256898e040dd
Autor:
Hans-Joachim Anders, Brad Rovin, David Jayne, Paul Brunetta, Rosanna Coppo, Anne Davidson, Satish Kumar Devarapu, Dick de Zeeuw, Jeremy Duffield, Dirk Eulberg, Alberto Fierro, Jürgen Floege, Steffen Frese, Loïc Guillevin, Stephen Holdsworth, Jeremy Hughes, Ralph Kettritz, Malte Kluger, Christian Krebs, Larissa Lapteva, Adeera Levin, Jinhua Li, Liz Lightstone, Matthias Mack, Ladan Mansouri, Stephen McAdoo, Eoin McKinney, Ulf Panzer, Samir Parikh, Charles Pusey, Chaim Putterman, Ton Rabelink, Andreas Radbruch, Andrew Rees, Mary Reilly, Marlies Reinders, Giuseppe Remuzzi, Piero Ruggenenti, Steven Sacks, Thomas J Schall, Catherine Meyer-Schwesinger, Kumar Sharma, Yusuke Suzuki, Nicola M. Tomas, Ming-Hui Zhao
Publikováno v:
Kidney International Reports, Vol 1, Iss 4, Pp 327-339 (2016)
To date, the treatment of immune-mediated kidney diseases has only marginally benefited from highly specific biological drugs that have demonstrated remarkable effects in many other diseases. What accounts for this disparity? In April 2016, the Inter
Externí odkaz:
https://doaj.org/article/31c0023f19ae480299b2c0347a697892
Autor:
Deborah Shan-Krauer, Thomas Kaufmann, Elena A. Federzoni, Magali Humbert, Steffen Frese, Aladin Haimovici, Thomas Brunner, Bruce E. Torbett, Mario P. Tschan
Publikováno v:
Cell Death Differ
The hematopoietic Ets-domain transcription factor PU.1/SPI1 orchestrates myeloid, B- and T-cell development, and also supports hematopoietic stem cell maintenance. Although PU.1 is a renowned tumor suppressor in acute myeloid leukemia (AML), a diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a68f90fa6806669e2610a62d85a43bd5
Autor:
Steffen Frese, Ralph A. Schmid, Selina Steiner, Manuela Frese-Schaper, Meike Körner, Andreas Keil
Publikováno v:
Arthritis & Rheumatology. 67:1858-1867
Objective The treatment of lupus nephritis is still an unmet medical need requiring new therapeutic approaches. Our group found recently that irinotecan, an inhibitor of topoisomerase I (topo I), reversed proteinuria and prolonged survival in mice wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d24806d6418377cbf3e8bf516aa279e
https://doi.org/10.1002/art.39119
https://doi.org/10.1002/art.39119
Autor:
Andreas Keil, Werner Falk, Manuela Frese-Schaper, Selina Steiner, Hideo Yagita, Steffen Frese, Ralph A. Schmid
Publikováno v:
Frese-Schaper, Manuela; Keil, Andreas; Yagita, Hideo; Steiner, Selina; Falk, Werner; Schmid, Ralph; Frese, Steffen R. (2014). Influence of natural killer cells and perforin-mediated cytolysis on the development of chemically induced lung cancer in A/J mice. Cancer immunology, immunotherapy, 63(6), pp. 571-580. Springer 10.1007/s00262-014-1535-x
One alternative approach for the treatment of lung cancer might be the activation of the immune system using vaccination strategies. However, most of clinical vaccination trials for lung cancer did not reach their primary end points, suggesting that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654e20dda4127e0048e13e81b0ab7148
https://doi.org/10.1007/s00262-014-1535-x
https://doi.org/10.1007/s00262-014-1535-x
Publikováno v:
Journal of thoracic disease. 8(10)
Background: Video-assisted mediastinoscopy (VAM) represents the standard procedure for mediastinal lymph node biopsies. This operation results in a scar at prominent position at the anterior neck. Since there is a trend to less invasive procedures, n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a34b69c5f78f0273997824a92b928cf6
https://pubmed.ncbi.nlm.nih.gov/27867546
https://pubmed.ncbi.nlm.nih.gov/27867546
Autor:
Wolfram Bremser, Gunda Leschber, Kristin Schallschmidt, Roland Becker, Jens Neudecker, Christian Jung, Steffen Frese, Irene Nehls, Thorsten Walles
Publikováno v:
Journal of breath research. 10(4)
This paper outlines the design and performance of an observational study on the profiles of volatile organic compounds (VOCs) in the breath of 37 lung cancer patients and 23 healthy controls of similar age. The need to quantify each VOC considered as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9b56fbd8c7d8935b2b8c618c0e3648
https://pubmed.ncbi.nlm.nih.gov/27732569
https://pubmed.ncbi.nlm.nih.gov/27732569
Autor:
Steven H. Sacks, Ming Hui Zhao, Piero Ruggenenti, Ralph Kettritz, Stephen R. Holdsworth, Steffen Frese, Kumar Sharma, Liz Lightstone, Hans-Joachim Anders, Jeremy S. Duffield, Rosanna Coppo, Alberto Fierro, Dick de Zeeuw, Ladan Mansouri, Jeremy Hughes, Nicola M. Tomas, Stephen P. McAdoo, Chaim Putterman, Adeera Levin, Yusuke Suzuki, Paul Brunetta, Andrew J. Rees, Samir M. Parikh, Loïc Guillevin, Satish Kumar Devarapu, Catherine Meyer-Schwesinger, Ton J. Rabelink, Larissa Lapteva, Thomas J. Schall, Christian Krebs, Charles D. Pusey, Mary Reilly, Anne Davidson, Jürgen Floege, Jinhua Li, Brad H. Rovin, Giuseppe Remuzzi, Eoin F. McKinney, Ulf Panzer, Dirk Eulberg, Malte A. Kluger, David Jayne, Matthias Mack, Andreas Radbruch, Marlies E.J. Reinders
Publikováno v:
Kidney International Reports, Vol 1, Iss 4, Pp 327-339 (2016)
Kidney International Reports, 1(4), 327-339
Kidney International Reports
Kidney international / Reports 1(4), 327-339 (2016). doi:10.1016/j.ekir.2016.06.009
Anders, H J, Rovin, B, Jayne, D, Brunetta, P, Coppo, R, Davidson, A, Devarapu, S K, de Zeeuw, D, Duffield, J, Eulberg, D, Fierro, A, Floege, J, Frese, S, Guillevin, L, Holdsworth, S, Hughes, J, Kettritz, R, Kluger, M, Krebs, C, Lapteva, L, Levin, A, Li, J, Lightstone, L, Mack, M, Mansouri, L, McAdoo, S, McKinney, E, Panzer, U, Parikh, S, Pusey, C, Putterman, C, Rabelink, T, Radbruch, A, Rees, A, Reilly, M, Reinders, M, Remuzzi, G, Ruggenenti, P, Sacks, S, Schall, T J, Meyer-Schwesinger, C, Sharma, K, Suzuki, Y, Tomas, N M & Zhao, M H 2016, ' ISN Nexus 2016 Symposia : Translational Immunology in Kidney Disease—The Berlin Roadmap ', Kidney International Reports, vol. 1, no. 4, pp. 327-339 . https://doi.org/10.1016/j.ekir.2016.06.009
Kidney International Reports, 1(4), 327-339. ELSEVIER SCIENCE INC
Kidney International Reports, 1(4), 327-339
Kidney International Reports
Kidney international / Reports 1(4), 327-339 (2016). doi:10.1016/j.ekir.2016.06.009
Anders, H J, Rovin, B, Jayne, D, Brunetta, P, Coppo, R, Davidson, A, Devarapu, S K, de Zeeuw, D, Duffield, J, Eulberg, D, Fierro, A, Floege, J, Frese, S, Guillevin, L, Holdsworth, S, Hughes, J, Kettritz, R, Kluger, M, Krebs, C, Lapteva, L, Levin, A, Li, J, Lightstone, L, Mack, M, Mansouri, L, McAdoo, S, McKinney, E, Panzer, U, Parikh, S, Pusey, C, Putterman, C, Rabelink, T, Radbruch, A, Rees, A, Reilly, M, Reinders, M, Remuzzi, G, Ruggenenti, P, Sacks, S, Schall, T J, Meyer-Schwesinger, C, Sharma, K, Suzuki, Y, Tomas, N M & Zhao, M H 2016, ' ISN Nexus 2016 Symposia : Translational Immunology in Kidney Disease—The Berlin Roadmap ', Kidney International Reports, vol. 1, no. 4, pp. 327-339 . https://doi.org/10.1016/j.ekir.2016.06.009
Kidney International Reports, 1(4), 327-339. ELSEVIER SCIENCE INC
To date, the treatment of immune-mediated kidney diseases has only marginally benefited from highly specific biological drugs that have demonstrated remarkable effects in many other diseases. What accounts for this disparity? In April 2016, the Inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8a6c1eec9e0548e1295aca329fb615
http://hdl.handle.net/10044/1/53394
http://hdl.handle.net/10044/1/53394
