Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Steffen Flemming"'
Autor:
Uwe Scholz, Christian Colmsee, Matthias Lange, Daniel Arend, Steffen Flemming, Denny Hecht, Jinbo Chen
Publikováno v:
BMC Bioinformatics
The life-science community faces a major challenge in handling “big data”, highlighting the need for high quality infrastructures capable of sharing and publishing research data. Data preservation, analysis, and publication are the three pillars
Publikováno v:
Synthesis. 1995:317-320
Publikováno v:
Liebigs Annalen. 1995:401-406
Regioselectivities in Michael-type reactions of organoaluminium and organotitanium reagents with sterically hindered carbonyl compounds 1 and 5 concerning 1,2- versus 1,4-addition were determined. Throughout this investigation Me3Al/cat. Ni(acac)2 wa
Publikováno v:
Tetrahedron. 51:743-754
The Michael-type reaction of copper-catalyzed trialkylaluminium reagents with α,β-unsaturated carbonyl compounds is a useful and simple procedure for the transfer of hydrocarbon substituents. The scope of this process and the effect of chlorotrimet
Publikováno v:
BIBM Workshops
Background: Life sciences are data intensive. High throughput technologies, like "Next-Generation-Sequencing", "Phenotyping" and other -omics technologies produce a huge amount of primary data. In classic scientific publication process, primary data
Publikováno v:
Tetrahedron Letters. 35:8591-8594
The effect of silanes as additives in the copper-catalyzed conjugate alkylation of enones by various organoaluminium reagents was investigated. TMSCl led to significant lower amounts of CuBr catalyst needed in the reaction of trimethylaluminium with
Publikováno v:
Chemische Berichte. 127:1489-1493
The conjugate methylation of α,β-unsaturated ketones with trimethylaluminium occurs smoothly in a very simple procedure under the catalytic effect of Cu1 salts. Scope and limitations of this process as well as the influence of solvent and catalyst
Publikováno v:
Tetrahedron Letters. 35:6075-6078
The 1,4-addition of organotitanium ate complexes to enones by nickel catalysis is reported. With a methyltitanium ate complex good yields of conjugate addition to sterically hindered enones are achieved. Phenyltitanium ate complexes react with less s
Publikováno v:
The Journal of Organic Chemistry. 58:3252-3258
A general enzymatic asymmetric synthesis of L-a-amino acids has been developed. This method entails the use of the Pseudomonas cepocio lipase (P-30) to catalyze the enantioselective methanolysis of a variety of 4-substituted 2-phenyloxazolin-5-one de
Autor:
Uwe Scholz, Christian Colmsee, Jinbo Chen, Matthias Klapperstück, Steffen Flemming, Matthias Lange
Publikováno v:
Nature Precedings.
Retrieval and citation of primary data is the important factor in the approaching age of “data science”. Digital data are easily shared, and just as easily wiped or lost. The problem of keeping on-line data accessible and retrievable is especiall