Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Steffen Dickel"'
Autor:
Martin S. Winkler, Marcin F. Osuchowski, Didier Payen, Antoni Torres, Steffen Dickel, Tomasz Skirecki
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-9 (2022)
Abstract The 40-year-old experience with glucocorticosteroids (GCs) in the context of severe infections is complex and troublesome. Recently, however, a clear indication for GCs in severe COVID-19 has been established. This may constitute a harbinger
Externí odkaz:
https://doaj.org/article/d92257ae52944d7ba25583a50b151b7b
Autor:
Clemens Grimm, Steffen Dickel, Julian Grundmann, Didier Payen, Julie Schanz, Andreas Erich Zautner, Björn Tampe, Onnen Moerer, Martin Sebastian Winkler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundCD14+ monocytes present antigens to adaptive immune cells via monocytic human leukocyte antigen receptor (mHLA-DR), which is described as an immunological synapse. Reduced levels of mHLA-DR can display an acquired immune defect, which is of
Externí odkaz:
https://doaj.org/article/9b782a31626c476eaa3599e4554c17fa
Autor:
Prerna Arora, Lu Zhang, Cheila Rocha, Luise Graichen, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Gema Morillas Ramos, Eva Baier, Björn Tampe, Onnen Moerer, Steffen Dickel, Martin S. Winkler, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14057 (2022)
Recently, a recombinant SARS-CoV-2 lineage, XD, emerged that harbors a spike gene that is largely derived from the Omicron variant BA.1 in the genetic background of the Delta variant. This finding raised concerns that the recombinant virus might exhi
Externí odkaz:
https://doaj.org/article/14c4ce1145744cba81384e99b38a7b6f
Autor:
Anne Werner, Maria Popp, Falk Fichtner, Christopher Holzmann-Littig, Peter Kranke, Anke Steckelberg, Julia Lühnen, Lisa Marie Redlich, Steffen Dickel, Clemens Grimm, Onnen Moerer, Monika Nothacker, Christian Seeber
Publikováno v:
Healthcare, Vol 10, Iss 7, p 1315 (2022)
Backround: In February 2021, the first formal evidence and consensus-based (S3) guidelines for the inpatient treatment of patients with COVID-19 were published in Germany and have been updated twice during 2021. The aim of the present study is to re-
Externí odkaz:
https://doaj.org/article/d002ada382f64b22b54cb97e12abe46f
Autor:
Steffen Dickel, Clemens Grimm, Katharina Amschler, Sebastian Uwe Schnitzler, Julie Schanz, Onnen Moerer, Didier Payen, Bjoern Tampe, Martin Sebastian Winkler
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundThe major histocompatibility complex (MHC) class II characterized by monocytes CD14+ expression of human leukocyte antigen receptors (HLA-DR), is essential for the synapse between innate and adaptive immune response in infectious disease. I
Externí odkaz:
https://doaj.org/article/a972ef65badf4d4b86d682758416401e
Autor:
Steffen Dickel, Clemens Grimm, Maria Popp, Claudia Struwe, Alexandra Sachkova, Martin Golinski, Christian Seeber, Falk Fichtner, Daniel Heise, Peter Kranke, Winfried Meissner, Sven Laudi, Sebastian Voigt-Radloff, Joerg Meerpohl, Onnen Moerer, on behalf of the German CEOsys Study Group
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 15, p 3363 (2021)
Introduction: Coronavirus disease (COVID-19) has recently dominated scientific literature. Incomplete understanding and a lack of data concerning the pathophysiology, epidemiology, and optimal treatment of the disease has resulted in conflicting reco
Externí odkaz:
https://doaj.org/article/ed6a142d38374beda44f0e91043f72df
Autor:
Anke Steckelberg, Ap CEOsys, Joerg J Meerpohl, Maria Popp, Onnen Moerer, Georg Holger Wormer, Jörg Wipplinger, Falk Fichtner, Steffen Dickel, Stephanie Weibel, Marjo Wijnen-Meijer, Peter Kranke, Christoph Schmaderer, Patrick Meybohm, Karolina Dahms, Clemens Grimm, Astrid Viciano, Carina Benstöm, Julia Krieger, Kelly Ansems, Julia Lühnen, Christopher Holzmann-Littig, Anne Werner, Marcus Anhäuser, Christian Seeber
Publikováno v:
Der Anaesthesist. 71:281-290
Zusammenfassung Hintergrund Das COVID-19-Evidenz-Ökosystem (CEOsys) identifiziert, bewertet und fasst Ergebnisse wissenschaftlicher Studien in Evidenzsynthesen im Kontext von COVID-19 zusammen. Diese Evidenzsynthesen werden genutzt, um konkrete Hand
Autor:
Prerna Arora, Inga Nehlmeier, Amy Kempf, Anne Cossmann, Sebastian R Schulz, Alexandra Dopfer-Jablonka, Eva Baier, Björn Tampe, Onnen Moerer, Steffen Dickel, Martin S Winkler, Hans-Martin Jäck, Georg M N Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
The Lancet Infectious Diseases. 22:1537-1538
Autor:
Friedrich Hohmann, Lisa Wedekind, Felicitas Grundeis, Steffen Dickel, Johannes Frank, Martin Golinski, Mirko Griesel, Clemens Grimm, Cindy Herchenhahn, Andre Kramer, Maria-Inti Metzendorf, Onnen Moerer, Nancy Olbrich, Volker Thieme, Astrid Vieler, Falk Fichtner, Jacob Burns, Sven Laudi
Publikováno v:
Cochrane Database Syst Rev
BACKGROUND: Acute respiratory distress syndrome (ARDS) represents the most severe course of COVID‐19 (caused by the SARS‐CoV‐2 virus), usually resulting in a prolonged stay in an intensive care unit (ICU) and high mortality rates. Despite the f
Autor:
Claudia Struwe, Martin Golinski, Clemens Grimm, Steffen Dickel, Kathrin Grummich, Monika Nothacker, Sebastian Voigt-Radloff, Jörg Meerpohl, Onnen Moerer
Publikováno v:
Dtsch Arztebl Int
BACKGROUND: When the SARS-CoV-2 pandemic began, no uniform treatment and care strategies for critically ill COVID-19 patients were yet available. National and international treatment recommendations were formulated under time pressure, initially on t