Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Steffen, Löck"'
Autor:
Iram Shahzadi, Annekatrin Seidlitz, Bettina Beuthien-Baumann, Alex Zwanenburg, Ivan Platzek, Jörg Kotzerke, Michael Baumann, Mechthild Krause, Esther G. C. Troost, Steffen Löck
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Personalized treatment strategies based on non-invasive biomarkers have potential to improve patient management in patients with newly diagnosed glioblastoma (GBM). The residual tumour burden after surgery in GBM patients is a prognostic ima
Externí odkaz:
https://doaj.org/article/0cb44df618b04c51a1088cc64d371f11
Autor:
Felix Schön, Aaron Kieslich, Heiner Nebelung, Carina Riediger, Ralf-Thorsten Hoffmann, Alex Zwanenburg, Steffen Löck, Jens-Peter Kühn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract To examine the comparative robustness of computed tomography (CT)-based conventional radiomics and deep-learning convolutional neural networks (CNN) to predict overall survival (OS) in HCC patients. Retrospectively, 114 HCC patients with pre
Externí odkaz:
https://doaj.org/article/ad7a4a29dc334dd883deb434c8699dc8
Autor:
Johanna Kirchner, Ioana Plesca, Rebecca Rothe, Antonia Resag, Steffen Löck, Iva Benešová, Luise Rupp, Annett Linge, Rebekka Wehner, Mechthild Krause, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Head and neck squamous cell carcinoma (HNSCC) is one of the most common tumor entities worldwide, with human papillomavirus (HPV) infection contributing to cancer development. Conventional therapies achieve only limited efficiency, especially in recu
Externí odkaz:
https://doaj.org/article/2da60e4d39b345af92e2abb592f98e57
Autor:
Josefine Metzkes-Ng, Florian-Emanuel Brack, Florian Kroll, Constantin Bernert, Stefan Bock, Elisabeth Bodenstein, Michael Brand, Thomas E. Cowan, René Gebhardt, Stefan Hans, Uwe Helbig, Felix Horst, Jeannette Jansen, Stephan D. Kraft, Mechthild Krause, Elisabeth Leßmann, Steffen Löck, Jörg Pawelke, Thomas Püschel, Marvin Reimold, Martin Rehwald, Christian Richter, Hans-Peter Schlenvoigt, Ulrich Schramm, Michael Schürer, Joao Seco, Emília Rita Szabó, Marvin E. P. Umlandt, Karl Zeil, Tim Ziegler, Elke Beyreuther
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract The recently observed FLASH effect describes the observation of normal tissue protection by ultra-high dose rates (UHDR), or dose delivery in a fraction of a second, at similar tumor-killing efficacy of conventional dose delivery and promise
Externí odkaz:
https://doaj.org/article/3adea7ce7b744f1eb0c55d7301e3c267
Autor:
Lydia Koi, Verena Bitto, Corina Weise, Lisa Möbius, Annett Linge, Steffen Löck, Ala Yaromina, María José Besso, Chiara Valentini, Manuel Pfeifer, Jens Overgaard, Daniel Zips, Ina Kurth, Mechthild Krause, Michael Baumann
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Tumor hypoxia is associated with resistance to radiotherapy and chemotherapy. In head and neck squamous cell carcinoma (HNSCC), nimorazole, an oxygen mimic, combined with radiotherapy (RT) enabled to improve loco-regional control
Externí odkaz:
https://doaj.org/article/ef4ef6625b6940398e45aefa8c370d20
Autor:
Nithya Bhasker, Fiona R. Kolbinger, Nadiia Skorobohach, Alex Zwanenburg, Steffen Löck, Jürgen Weitz, Ralf-Thorsten Hoffmann, Marius Distler, Stefanie Speidel, Stefan Leger, Jens-Peter Kühn
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Clinically relevant postoperative pancreatic fistula (CR-POPF) can significantly affect the treatment course and outcome in pancreatic cancer patients. Preoperative prediction of CR-POPF can aid the surgical decision-making process and lead
Externí odkaz:
https://doaj.org/article/c2fe9d8094744d5589caba4c80c902b4
Publikováno v:
Frontiers in Physics, Vol 11 (2023)
Robust and fast in vivo treatment verification is expected to increase the clinical efficacy of proton therapy. The combined detection of prompt gamma rays and neutrons has recently been proposed for this purpose and shown to increase the monitoring
Externí odkaz:
https://doaj.org/article/83dd10ff63664c4ca02c3b19b76cae59
Autor:
Iñaki Schniewind, Maria José Besso, Sebastian Klicker, Franziska Maria Schwarz, Wahyu Wijaya Hadiwikarta, Susan Richter, Steffen Löck, Annett Linge, Mechthild Krause, Anna Dubrovska, Michael Baumann, Ina Kurth, Claudia Peitzsch
Publikováno v:
Cancers, Vol 16, Iss 4, p 730 (2024)
(1) Background: The sensitivity of head and neck squamous cell carcinoma (HNSCC) to ionizing radiation, among others, is determined by the number of cells with high clonogenic potential and stem-like features. These cellular characteristics are dynam
Externí odkaz:
https://doaj.org/article/83e3524b7dc14bd592f79225adf307d4
Autor:
Asier Rabasco Meneghetti, Alex Zwanenburg, Annett Linge, Fabian Lohaus, Marianne Grosser, Gustavo B. Baretton, Goda Kalinauskaite, Ingeborg Tinhofer, Maja Guberina, Martin Stuschke, Panagiotis Balermpas, Jens von der Grün, Ute Ganswindt, Claus Belka, Jan C. Peeken, Stephanie E. Combs, Simon Böke, Daniel Zips, Esther G. C. Troost, Mechthild Krause, Michael Baumann, Steffen Löck
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) may benefit from personalised treatment, requiring biomarkers that characterize the tumour and predict treatment response. We integrate pre-treatment CT radiomics a
Externí odkaz:
https://doaj.org/article/c1dcd98b39744271b0c678eabb5a6b58
Autor:
Benjamin Terfa Igbo, Annett Linge, Susanne Frosch, Theresa Suckert, Liane Stolz-Kieslich, Steffen Löck, Mani Sankari Kumaravadivel, Thilo Welsch, Jürgen Weitz, Ulrich Sommer, Daniela Aust, Esther G.C. Troost
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 36, Iss , Pp 106-112 (2022)
Background: The microscopic tumor extension before, during or after radiochemotherapy (RCHT) and its correlation with the tumor microenvironment (TME) are presently unknown. This information is, however, crucial in the era of image-guided, adaptive h
Externí odkaz:
https://doaj.org/article/05538a565f874080808ebfc63005fccf