Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Steffen, Jockusch"'
Autor:
Shanshan Hou, Xin Yan, Xiang Gao, Steffen Jockusch, K. Michael Gibson, Zhiying Shan, Lanrong Bi
Publikováno v:
ACS Omega, Vol 9, Iss 38, Pp 39401-39418 (2024)
Externí odkaz:
https://doaj.org/article/33e22b79ab4d43d3897f1dd5ff1439ad
Autor:
Xammy Nguyenla, Eddie Wehri, Erik Van Dis, Scott B. Biering, Livia H. Yamashiro, Chi Zhu, Julien Stroumza, Claire Dugast-Darzacq, Thomas G. W. Graham, Xuanting Wang, Steffen Jockusch, Chuanjuan Tao, Minchen Chien, Wei Xie, Dinshaw J. Patel, Cindy Meyer, Aitor Garzia, Thomas Tuschl, James J. Russo, Jingyue Ju, Anders M. Näär, Sarah Stanley, Julia Schaletzky
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract SARS coronavirus 2 (SARS-CoV-2) has caused an ongoing global pandemic with significant mortality and morbidity. At this time, the only FDA-approved therapeutic for COVID-19 is remdesivir, a broad-spectrum antiviral nucleoside analog. Efficac
Externí odkaz:
https://doaj.org/article/9e4aeb4597b84bd5b8c7f7298e96338a
Autor:
Xuanting Wang, Carolina Q. Sacramento, Steffen Jockusch, Otávio Augusto Chaves, Chuanjuan Tao, Natalia Fintelman-Rodrigues, Minchen Chien, Jairo R. Temerozo, Xiaoxu Li, Shiv Kumar, Wei Xie, Dinshaw J. Patel, Cindy Meyer, Aitor Garzia, Thomas Tuschl, Patrícia T. Bozza, James J. Russo, Thiago Moreno L. Souza, Jingyue Ju
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
In this paper, the hepatitis C virus inhibitors Pibrentasvir and Ombitasvir are found to inhibit the SARS-CoV-2 exonuclease and are shown to have therapeutic potential when combined with SARS-CoV-2 polymerase inhibitors in viral cell cultures.
Externí odkaz:
https://doaj.org/article/421885d8a61b464da42eeec94cc924d8
Autor:
Nazmiye B. Yapici, Xiang Gao, Xin Yan, Shanshan Hou, Steffen Jockusch, Lillian Lesniak, K. Michael Gibson, Lanrong Bi
Publikováno v:
ACS Omega, Vol 6, Iss 47, Pp 31447-31456 (2021)
Externí odkaz:
https://doaj.org/article/a8002a292f8a4fc7b531da388c4465e3
Autor:
Luis A. Ortiz-Rodríguez, Christian Reichardt, Sean J. Hoehn, Steffen Jockusch, Carlos E. Crespo-Hernández
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The mechanisms of formation of the (6-4) photoproducts in DNA damage by sunlight is still debated. Here the authors show, by optical spectroscopies and computations, the details of the formation of a (6-4) photoadduct via the thietane intermediate in
Externí odkaz:
https://doaj.org/article/343811f9b7a74c7babd79d0230667245
Autor:
Brianna F. Moon, Srikant Kamesh Iyer, Eileen Hwuang, Michael P. Solomon, Anya T. Hall, Rishabh Kumar, Nicholas J. Josselyn, Elizabeth M. Higbee-Dempsey, Andrew Tsourkas, Akito Imai, Keitaro Okamoto, Yoshiaki Saito, James J. Pilla, Joseph H. Gorman, Robert C. Gorman, Cory Tschabrunn, Samuel J. Keeney, Estibaliz Castillero, Giovanni Ferrari, Steffen Jockusch, Felix W. Wehrli, Haochang Shou, Victor A. Ferrari, Yuchi Han, Avanti Gulhane, Harold Litt, William Matthai, Walter R. Witschey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Restoration of coronary blood flow after a heart attack may lead to reperfusion injury and pathologic iron deposition. Here, the authors perform magnetic susceptibility imaging showing its association with iron in a large animal model of myocardial i
Externí odkaz:
https://doaj.org/article/dc0dc96d8d144bd499b64b7fc318dcc8
Autor:
Wei Bi, Yue Bi, Pengfei Li, Shanshan Hou, Xin Yan, Connor Hensley, Yanrong Zhang, Steffen Jockusch, Thomas D. Legalley, K. Michael Gibson, Lanrong Bi
Publikováno v:
ACS Omega, Vol 4, Iss 6, Pp 9868-9877 (2019)
Externí odkaz:
https://doaj.org/article/7632039cd64b42549fa9a88e2a8975bb
Autor:
Sruthy Baburaj, Jayachandran Parthiban, Sarvar Aminovich Rakhimov, Rasheedah Johnson, Ludmila Sukhomlinova, Paul Luchette, Steffen Jockusch, Malcolm D. E. Forbes, Jayaraman Sivaguru
Publikováno v:
Photochemistry and Photobiology. 99:901-905
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9faf7c5d782d3d6f50f89f9c06c0615b
https://doi.org/10.1111/php.13795
https://doi.org/10.1111/php.13795
Autor:
Jingyue Ju, Xiaoxu Li, Shiv Kumar, Steffen Jockusch, Minchen Chien, Chuanjuan Tao, Irina Morozova, Sergey Kalachikov, Robert N. Kirchdoerfer, James J. Russo
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 6, Pp n/a-n/a (2020)
Abstract SARS‐CoV‐2, a member of the coronavirus family, has caused a global public health emergency. Based on our analysis of hepatitis C virus and coronavirus replication, and the molecular structures and activities of viral inhibitors, we prev
Externí odkaz:
https://doaj.org/article/c4e280e62da0401999fbdd345e4fd779
Autor:
Sean J. Hoehn, Glesmarie Ortiz-Zayas, Luis A. Ortiz-Rodríguez, Steffen Jockusch, Carlos E. Crespo-Hernández, Marvin Pollum
Publikováno v:
Photochemistry and Photobiology. 98:617-632
The thiopurine prodrugs 6-mercaptopurine and azathioprine are among the world's essential medications for acute lymphoblastic leukemia, immunosuppression and several autoimmune conditions. Thiopurine prodrugs are efficient UVA absorbers and singlet o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1b53d6e47b4dcc67a2a7c2df2f7cab
https://doi.org/10.1111/php.13513
https://doi.org/10.1111/php.13513