Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Stefanos Leptidis"'
Autor:
Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
To define and distinguish fibroblasts from vascular mural cells have remained challenging. Here, using single-cell RNA sequencing and tissue imaging, the authors provide a molecular basis for cell type classification and reveal inter- and intra-organ
Externí odkaz:
https://doaj.org/article/5f2bea014f994236b4d2abd38b628f2e
Autor:
Lars Muhl, Guillem Genové, Stefanos Leptidis, Jianping Liu, Liqun He, Giuseppe Mocci, Ying Sun, Sonja Gustafsson, Byambajav Buyandelger, Indira V. Chivukula, Åsa Segerstolpe, Elisabeth Raschperger, Emil M. Hansson, Johan L. M. Björkegren, Xiao-Rong Peng, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/83c57908db664426b1e35cc001aef2b7
Autor:
Stefanos Leptidis, Hamid el Azzouzi, Sjoukje I. Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J. Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J. De Windt, Paula da Costa Martins
Publikováno v:
PLoS ONE, Vol 8, Iss 6 (2013)
Externí odkaz:
https://doaj.org/article/e4264c325e224ee6885cd7677169bc69
Autor:
Stefanos Leptidis, Hamid El Azzouzi, Sjoukje I Lok, Roel de Weger, Servé Olieslagers, Natasja Kisters, Gustavo J Silva, Stephane Heymans, Edwin Cuppen, Eugene Berezikov, Leon J De Windt, Paula da Costa Martins
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57800 (2013)
MicroRNAs (miRNAs) are a class of non-coding RNAs of ∼22 nucleotides in length, and constitute a novel class of gene regulators by imperfect base-pairing to the 3'UTR of protein encoding messenger RNAs. Growing evidence indicates that miRNAs are im
Externí odkaz:
https://doaj.org/article/4f5e890bfdfe449ba35aa7018a154ce6
Autor:
Hamid el Azzouzi, Stefanos Leptidis, Meriem Bourajjaj, Marc van Bilsen, Paula A da Costa Martins, Leon J De Windt
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36799 (2012)
BACKGROUND: The response of the postnatal heart to growth and stress stimuli includes activation of a network of signal transduction cascades, including the stress activated protein kinases such as p38 mitogen-activated protein kinase (MAPK), c-Jun N
Externí odkaz:
https://doaj.org/article/2160f88c15f34659b8fda4adaa398a24
Autor:
Katerina Pierouli, Louis Papageorgiou, Thanasis Mitsis, Eleni Papakonstantinou, Io Diakou, Stefanos Leptidis, Markezina Sigala, Konstantina Dragoumani, Demetrios Spandidos, Flora Bacopoulou, George Chrousos, George Goulielmos, Elias Eliopoulos, Dimitrios Vlachakis
Publikováno v:
International journal of molecular medicine. 50(6)
The synthesis and release of glucocorticoids in living organisms are related to their response to unfavorable stressful conditions in order to maintain homeostatic functions and survive. One such hormone in humans is cortisol, which is produced by th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f20b03efd446967a2c386d15f926e3
https://pubmed.ncbi.nlm.nih.gov/36367164
https://pubmed.ncbi.nlm.nih.gov/36367164
Autor:
Lars Muhl, Liqun He, Ying Sun, Maarja Andaloussi Mäe, Riikka Pietilä, Jianping Liu, Guillem Genové, Lei Zhang, Yuan Xie, Stefanos Leptidis, Giuseppe Mocci, Simon Stritt, Ahmed Osman, Andrey Anisimov, Karthik Amudhala Hemanthakumar, Markus Räsänen, Emil M. Hansson, Johan Björkegren, Michael Vanlandewijck, Klas Blomgren, Taija Mäkinen, Xiao-Rong Peng, Yizhou Hu, Patrik Ernfors, Thomas D. Arnold, Kari Alitalo, Urban Lendahl, Christer Betsholtz
Humanized mouse models and mouse-adapted SARS-CoV-2 virus are increasingly used to study COVID-19 pathogenesis, so it is impor-tant to learn where the SARS-CoV-2 receptor ACE2 is expressed. Here we mapped ACE2 expression during mouse postnatal develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48773163c4f779200f287930f67ceac5
http://hdl.handle.net/10138/345993
http://hdl.handle.net/10138/345993
Autor:
Lars Muhl, Giuseppe Mocci, Riikka Pietilä, Jianping Liu, Liqun He, Guillem Genové, Stefanos Leptidis, Sonja Gustafsson, Byambajav Buyandelger, Elisabeth Raschperger, Emil M. Hansson, Johan L.M. Björkegren, Michael Vanlandewijck, Urban Lendahl, Christer Betsholtz
Publikováno v:
Developmental Cell. 57:2426-2443.e6
Smooth muscle cells (SMCs) execute important physiological functions in numerous vital organ systems, including the vascular, gastrointestinal, respiratory, and urogenital tracts. SMC differ morphologically and functionally at these different anatomi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae5dc9171acddacb4a8099b7b6df9f3
https://doi.org/10.1016/j.devcel.2022.09.015
https://doi.org/10.1016/j.devcel.2022.09.015
Autor:
Ying Sun, Stefanos Leptidis, Elisabeth Raschperger, Giuseppe Mocci, Emil M. Hansson, Christer Betsholtz, Åsa Segerstolpe, Michael Vanlandewijck, Lars Muhl, Urban Lendahl, Indira V. Chivukula, Johan Björkegren, Liqun He, Xiao-Rong Peng, Jianping Liu, Byambajav Buyandelger, Sonja Gustafsson, Guillem Genové
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Many important cell types in adult vertebrates have a mesenchymal origin, including fibroblasts and vascular mural cells. Although their biological importance is undisputed, the level of mesenchymal cell heterogeneity within and between organs, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1ccd5b043e7dff45d755127de88de75
https://doi.org/10.1038/s41467-020-17740-1
https://doi.org/10.1038/s41467-020-17740-1
Autor:
Liqun He, Maarja Andaloussi Mäe, Lars Muhl, Ying Sun, Riikka Pietilä, Khayrun Nahar, Elisa Vázquez Liébanas, Malin Jonsson Fagerlund, Anders Oldner, Jianping Liu, Guillem Genové, Lei Zhang, Yuan Xie, Stefanos Leptidis, Giuseppe Mocci, Simon Stritt, Ahmed Osman, Andrey Anisimov, Karthik Amudhala Hemanthakumar, Markus Räsänen, Olivier Mirabeau, Emil Hansson, Johan Björkegren, Michael Vanlandewijck, Klas Blomgren, Taija Mäkinen, Xiao-Rong Peng, Thomas D. Arnold, Kari Alitalo, Lars I Eriksson, Urban Lendahl, Christer Betsholtz
Accumulating clinical observations suggest pathogenesis beyond viral pneumonia and its secondary consequences in COVID-19 patients. In particular, many patients develop profound hyperinflammation and hypercoagulopathy with disseminated thrombogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3397775b98e7a526555f144eae0dc907