Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Stefano Volinia"'
Autor:
Chiara Agnoletto, Stefano Volinia
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Circulating tumor cells (CTCs) represent a subset of heterogeneous cells, which, once released from a tumor site, have the potential to give rise to metastasis in secondary sites. Recent research focused on the attempt to detect and characterize thes
Externí odkaz:
https://doaj.org/article/0a602c11d00147edbfedcfce3b8fc9bc
Autor:
Anna Terrazzan, Francesca Crudele, Fabio Corrà, Pietro Ancona, Jeffrey Palatini, Nicoletta Bianchi, Stefano Volinia
Publikováno v:
Non-Coding RNA, Vol 9, Iss 3, p 32 (2023)
Altered expression of circular RNAs (circRNAs) has previously been investigated in breast cancer. However, little is known about the effects of drugs on their regulation and relationship with the cognate linear transcript (linRNA). We analyzed the dy
Externí odkaz:
https://doaj.org/article/d3ac689596b3411e93e855f71a4d1daa
Autor:
Francesca Crudele, Nicoletta Bianchi, Anna Terrazzan, Pietro Ancona, Antonio Frassoldati, Paolo Gasparini, Adamo P. D’Adamo, Dimitrios Papaioannou, Ramiro Garzon, Anna Wójcicka, Paweł Gaj, Krystian Jażdżewski, Jeffrey Palatini, Stefano Volinia
Publikováno v:
Biology, Vol 12, Iss 4, p 493 (2023)
circRNAs constitute a novel class of RNA, generally considered as non-coding RNAs; nonetheless, their coding potential has been under scrutiny. In this work, we systematically explored the predicted proteins of more than 160,000 circRNAs detected by
Externí odkaz:
https://doaj.org/article/8c2c52e673b74db09498bde1e19ca008
Autor:
Lei Shi, Peter Magee, Matteo Fassan, Sudhakar Sahoo, Hui Sun Leong, Dave Lee, Robert Sellers, Laura Brullé-Soumaré, Stefano Cairo, Tiziana Monteverde, Stefano Volinia, Duncan D. Smith, Gianpiero Di Leva, Francesca Galuppini, Athanasios R. Paliouras, Kang Zeng, Raymond O’Keefe, Michela Garofalo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Wild-type KRAS amplification is known to induce KRAS activation in cancer leading to poor prognostic outcomes. Here the authors identify a KRAS-responsive lncRNA, KIMAT1 that maintains KRAS signalling in lung cancer, suggesting that its targeting may
Externí odkaz:
https://doaj.org/article/befd75df391041c7bcbc529acaf3af0c
Autor:
Simona Giglio, Cosimo De Nunzio, Roberto Cirombella, Antonella Stoppacciaro, Omar Faruq, Stefano Volinia, Gustavo Baldassarre, Andrea Tubaro, Hideshi Ishii, Carlo M. Croce, Andrea Vecchione
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-12 (2021)
Abstract Background A prostate cancer diagnosis is based on biopsy sampling that is an invasive, expensive procedure, and doesn’t accurately represent multifocal disease. Methods To establish a model using plasma miRs to distinguish Prostate cancer
Externí odkaz:
https://doaj.org/article/a3fac88a02854441a9ea1cc8b8dba74c
Autor:
Rita Canella, Federica Brugnoli, Mariana Gallo, Jeffrey W. Keillor, Anna Terrazzan, Elena Ferrari, Silvia Grassilli, Eric W. J. Gates, Stefano Volinia, Valeria Bertagnolo, Nicoletta Bianchi, Carlo M. Bergamini
Publikováno v:
Cancers, Vol 15, Iss 1, p 178 (2022)
Since the multifunctionality of transglutaminase 2 (TG2) includes extra- and intracellular functions, we investigated the effects of intracellular administration of TG2 inhibitors in three breast cancer cell lines, MDA-MB-231, MDA-MB-436 and MDA-MB-4
Externí odkaz:
https://doaj.org/article/02db977e8efe4f2594ed286b5c7bf061
Autor:
Francesca Crudele, Nicoletta Bianchi, Eva Reali, Marco Galasso, Chiara Agnoletto, Stefano Volinia
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-18 (2020)
Abstract Background Non-coding RNAs are now recognized as fundamental components of the cellular processes. Non-coding RNAs are composed of different classes, including microRNAs (miRNAs) and long non-coding RNAs (lncRNAs). Their detailed roles in br
Externí odkaz:
https://doaj.org/article/be0b3ecbf5ff46acac0fe851c3f4b5f6
Autor:
Alice Ramassone, Andrea D’Argenio, Angelo Veronese, Alessio Basti, Shimaa Hassan AbdelAziz Soliman, Stefano Volinia, Cristian Bassi, Sara Pagotto, Manuela Ferracin, Laura Lupini, Elena Saccenti, Veronica Balatti, Felice Pepe, Laura Z. Rassenti, Idanna Innocenti, Francesco Autore, Laura Marzetti, Renato Mariani-Costantini, Thomas J. Kipps, Massimo Negrini, Luca Laurenti, Rosa Visone
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Clonal evolution of chronic lymphocytic leukemia (CLL) often follows chemotherapy and is associated with adverse outcome, but also occurs in untreated patients, in which case its predictive role is debated. We investigated whether the select
Externí odkaz:
https://doaj.org/article/c1332f4fd0124ad88fe36c7515842edf
Autor:
Dimitrios Papaioannou, Hatice G. Ozer, Deedra Nicolet, Amog P. Urs, Tobias Herold, Krzysztof Mrózek, Aarif M.N. Batcha, Klaus H. Metzeler, Ayse S. Yilmaz, Stefano Volinia, Marius Bill, Jessica Kohlschmidt, Maciej Pietrzak, Christopher J. Walker, Andrew J. Carroll, Jan Braess, Bayard L. Powell, Ann-Kathrin Eisfeld, Geoffrey L. Uy, Eunice S. Wang, Jonathan E. Kolitz, Richard M. Stone, Wolfgang Hiddemann, John C. Byrd, Clara D. Bloomfield, Ramiro Garzon
Publikováno v:
Haematologica, Vol 107, Iss 5 (2021)
Expression levels of long non-coding RNA (lncRNA) have been shown to associate with clinical outcome of patients with cytogenetically normal acute myeloid leukemia (CN-AML). However, the frequency and clinical significance of genetic variants in the
Externí odkaz:
https://doaj.org/article/7f9bf447eead48ccb2195be68f8f7b08
Autor:
Laura Lupini, Roberta Roncarati, Lorenzo Belluomini, Federica Lancia, Cristian Bassi, Lucilla D’Abundo, Angelo Michilli, Paola Guerriero, Alessandra Fasano, Elisa Tiberi, Andrea Salamone, Donato Michele Cosi, Elena Saccenti, Valentina Tagliatti, Iva Maestri, Silvia Sabbioni, Stefano Volinia, Roberta Gafà, Giovanni Lanza, Antonio Frassoldati, Massimo Negrini
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8546 (2022)
Liquid biopsy has advantages over tissue biopsy, but also some technical limitations that hinder its wide use in clinical applications. In this study, we aimed to evaluate the usefulness of liquid biopsy for the clinical management of patients with a
Externí odkaz:
https://doaj.org/article/817561af7fa543fc8a57a17fa89b125b