Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Stefano Schivo"'
Autor:
Sakshi Khurana, Stefano Schivo, Jacqueline R. M. Plass, Nikolas Mersinis, Jetse Scholma, Johan Kerkhofs, Leilei Zhong, Jaco van de Pol, Rom Langerak, Liesbet Geris, Marcel Karperien, Janine N. Post
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
A fundamental question in cartilage biology is: what determines the switch between permanent cartilage found in the articular joints and transient hypertrophic cartilage that functions as a template for bone? This switch is observed both in a subset
Externí odkaz:
https://doaj.org/article/7987b8cda5b64370984e24d6236274bd
Autor:
Stefano Schivo, Jetse Scholma, Marcel Karperien, Janine N. Post, Jaco van de Pol, Rom Langerak
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 145, Iss Proc. SynCoP 2014, Pp 35-47 (2014)
ANIMO (Analysis of Networks with Interactive MOdeling) is a software for modeling biological networks, such as e.g. signaling, metabolic or gene networks. An ANIMO model is essentially the sum of a network topology and a number of interaction paramet
Externí odkaz:
https://doaj.org/article/da95cd0e91104b5d887cbfbee9a024ba
Publikováno v:
Kammüller, F, Legay, A & Schivo, S 2021, ' Masterminding change by combining secure system design with security risk assessment ', International Journal on Software Tools for Technology Transfer, vol. 23, no. 1, 1, pp. 69-70 . https://doi.org/10.1007/s10009-020-00595-8
International Journal on Software Tools for Technology Transfer, 23(1):1, 69-70. Springer Verlag
International Journal on Software Tools for Technology Transfer, Vol. 23, no.1, p. 69-70 (2020)
International Journal on Software Tools for Technology Transfer, 23(1):1, 69-70. Springer Verlag
International Journal on Software Tools for Technology Transfer, Vol. 23, no.1, p. 69-70 (2020)
This track introduction presents the results of the Workshop on Security practices for Internet of Things, SPIoT held at ETAPS in Prague in April 2019. For this Special Issue of STTT, we have selected, invited and edited three distinguished papers. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d51685dacb3babb84d6f6513fc0a319e
https://hdl.handle.net/1820/e58d792d-8e00-4d3a-a71e-25d3721f2c4b
https://hdl.handle.net/1820/e58d792d-8e00-4d3a-a71e-25d3721f2c4b
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2221
Computational modeling of biological networks is increasing in popularity due to the increased demand for understanding biological processes. This understanding requires integration of a variety of experimental data that allows understanding of compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c725bba00cff466f2588906cd3ebd11a
https://pubmed.ncbi.nlm.nih.gov/32979203
https://pubmed.ncbi.nlm.nih.gov/32979203
Autor:
Jetse Scholma, Liesbet Geris, Janine N. Post, Jaco van de Pol, Sakshi Khurana, Rom Langerak, Stefano Schivo, Kannan Govindaraj, Johan Kerkhofs, Marcel Karperien, Xiaobin Huang, Andre J. van Wijnen, Leilei Zhong
Publikováno v:
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, van de Pol, J, Langerak, R, van Wijnen, A J, Geris, L, Karperien, M & Post, J N 2020, ' ECHO, the executable CHOndrocyte : A computational model to study articular chondrocytes in health and disease ', Cellular Signalling, vol. 68, 109471 . https://doi.org/10.1016/j.cellsig.2019.109471
Cellular Signalling, 68:109471. Elsevier Inc.
Cellular Signalling, 68:109471. Elsevier
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, Pol, J V D, Langerak, R, Wijnen, A J V, Geris, L, Karperien, M & Post, J N 2019, ' ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in healthy and disease ', Cellular Signalling . https://doi.org/10.1016/j.cellsig.2019.109471
Cellular Signalling, 68:109471. Elsevier Inc.
Cellular Signalling, 68:109471. Elsevier
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, Pol, J V D, Langerak, R, Wijnen, A J V, Geris, L, Karperien, M & Post, J N 2019, ' ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in healthy and disease ', Cellular Signalling . https://doi.org/10.1016/j.cellsig.2019.109471
Computational modeling can be used to investigate complex signaling networks in biology. However, most modeling tools are not suitable for molecular cell biologists with little background in mathematics. We have built a visual-based modeling tool for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dd3e18d306a6fd950ea89a5e3420b0
https://hdl.handle.net/1820/c8afbf16-bbcd-4716-a850-c0f96f5f0326
https://hdl.handle.net/1820/c8afbf16-bbcd-4716-a850-c0f96f5f0326
Autor:
Niven Mehra, Hendrik Koffijberg, Koen Degeling, Johann S. de Bono, Maarten Joost IJzerman, Romanus Langerak, Stefano Schivo
Publikováno v:
Value in Health, 20, 1411-1419
Value in Health, 20, 10, pp. 1411-1419
Value in Health, 20(10), 1411-1419. Elsevier Science Inc.
Value in health, 20(10), 1411-1419. Elsevier
Degeling, K, Schivo, S, Mehra, N, Koffijberg, H, Langerak, R, de Bono, J S & IJzerman, M J 2017, ' Comparison of Timed Automata with Discrete Event Simulation for Modeling of Biomarker-Based Treatment Decisions : An Illustration for Metastatic Castration-Resistant Prostate Cancer ', Value in Health, vol. 20, no. 10, pp. 1411-1419 . https://doi.org/10.1016/j.jval.2017.05.024
Value in Health, 20, 10, pp. 1411-1419
Value in Health, 20(10), 1411-1419. Elsevier Science Inc.
Value in health, 20(10), 1411-1419. Elsevier
Degeling, K, Schivo, S, Mehra, N, Koffijberg, H, Langerak, R, de Bono, J S & IJzerman, M J 2017, ' Comparison of Timed Automata with Discrete Event Simulation for Modeling of Biomarker-Based Treatment Decisions : An Illustration for Metastatic Castration-Resistant Prostate Cancer ', Value in Health, vol. 20, no. 10, pp. 1411-1419 . https://doi.org/10.1016/j.jval.2017.05.024
Item does not contain fulltext BACKGROUND: With the advent of personalized medicine, the field of health economic modeling is being challenged and the use of patient-level dynamic modeling techniques might be required. OBJECTIVES: To illustrate the u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3f2e9e123914d3e5b36a4b24c4c886
https://doi.org/10.1016/j.jval.2017.05.024
https://doi.org/10.1016/j.jval.2017.05.024
Autor:
Leilei Zhong1,2 zhongleilei8@gmail.com, Stefano Schivo1,3 s.schivo@utwente.nl, Xiaobin Huang1 x.huang-1@utwente.nl, Jeroen Leijten1 j.c.h.leijten@utwente.nl, Karperien, Marcel1 h.b.j.karperien@utwente.nl, Post, Janine N.1 j.n.post@utwente.nl
Publikováno v:
International Journal of Molecular Sciences. Nov2017, Vol. 18 Issue 11, preceding p2491. 18p.
Publikováno v:
Osteoarthritis and Cartilage, 27(S1), S193-S194. ELSEVIER SCI LTD
Khurana, S, Bokkers, A, Geijs, D J, Schivo, S, Karperien, M & Post, J N 2019, ' In Silico Validation of a cartilage specific circadian clock : mutation of BMAL1 increased MMP expression ', Osteoarthritis and Cartilage, vol. 27, no. S1, pp. S193-S194 . https://doi.org/10.1016/j.joca.2019.02.297
Osteoarthritis and cartilage, 27(suppl. 1), S193-S194. W.B. Saunders Ltd
Khurana, S, Bokkers, A, Geijs, D J, Schivo, S, Karperien, M & Post, J N 2019, ' In Silico Validation of a cartilage specific circadian clock : mutation of BMAL1 increased MMP expression ', Osteoarthritis and Cartilage, vol. 27, no. S1, pp. S193-S194 . https://doi.org/10.1016/j.joca.2019.02.297
Osteoarthritis and cartilage, 27(suppl. 1), S193-S194. W.B. Saunders Ltd
Purpose: Osteoarthritis (OA) is a complex, progressive degenerative cartilage disease involving remodeling of joint tissues. Several signaling pathways are involved in the pathogenesis of osteoarthritis. The intrinsic circadian clock is also known to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::908ac79f952c5b7b14aa93be5f6ad112
https://doi.org/10.1016/j.joca.2019.02.297
https://doi.org/10.1016/j.joca.2019.02.297
Autor:
Stefano Schivo, Janine N. Post, Jeroen Leijten, Marcel Karperien, Xiaobin Huang, Leilei Zhong
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 11, p 2491 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2491
International journal of molecular sciences, 18(11):2491. MDPI
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 11; Pages: 2491
International journal of molecular sciences, 18(11):2491. MDPI
International Journal of Molecular Sciences
Interleukin 1 beta (IL1β) and Wingless-Type MMTV Integration Site Family (WNT) signaling are major players in Osteoarthritis (OA) pathogenesis. Despite having a large functional overlap in OA onset and development, the mechanism of IL1β and WNT cro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f38fa0859e1292596304df159e423e9
https://www.mdpi.com/1422-0067/18/11/2491
https://www.mdpi.com/1422-0067/18/11/2491
Publikováno v:
2017 Annual Reliability and Maintainability Symposium (RAMS)
As the critical systems we rely on every day, such as nuclear power plants and airplanes, become ever more complex, the need to rigorously verify the safety and dependability of these systems is becoming very clear. Furthermore, deliberate attacks ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323b8057a489d5df2047ccf1bd6522b9
https://doi.org/10.1109/ram.2017.7889759
https://doi.org/10.1109/ram.2017.7889759