Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stefano Rovida"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The number of usable light-responsive enzymes is limited, despite the potential biotechnological applications. Here, the authors report a flavoprotein monooxygenase which is controllable by blue light illumination, and propose a mechanism involving p
Externí odkaz:
https://doaj.org/article/446dcc8c776447e7b172e6e017c89475
Autor:
Friso S Aalbers, Maximilian JLJ Fürst, Stefano Rovida, Milos Trajkovic, J Rubén Gómez Castellanos, Sebastian Bartsch, Andreas Vogel, Andrea Mattevi, Marco W Fraaije
Publikováno v:
eLife, Vol 9 (2020)
Enzyme instability is an important limitation for the investigation and application of enzymes. Therefore, methods to rapidly and effectively improve enzyme stability are highly appealing. In this study we applied a computational method (FRESCO) to g
Externí odkaz:
https://doaj.org/article/9ea0cafaa246482182ba4ca34009153e
Publikováno v:
'Nature Communications ', vol: 11, pages: 2600-1-2600-11 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Light-dependent or light-stimulated catalysis provides a multitude of perspectives for implementation in technological or biomedical applications. Despite substantial progress made in the field of photobiocatalysis, the number of usable light-respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1394099a0d18ef4ad34bf1acef2d66a4
https://doi.org/10.1038/s41467-020-16450-y
https://doi.org/10.1038/s41467-020-16450-y
Autor:
Stefano Rovida, Milos Trajkovic, Andrea Mattevi, Marco W. Fraaije, Sebastian Bartsch, Maximilian J. L. J. Fürst, J. Rubén Gómez Castellanos, Friso S. Aalbers, Andreas Vogel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a52bb6f344fddc7f58f5636583083aa7
https://doi.org/10.7554/elife.54639.sa2
https://doi.org/10.7554/elife.54639.sa2
Autor:
Andreas Vogel, Friso S. Aalbers, Milos Trajkovic, Sebastian Bartsch, Andrea Mattevi, J. Rubén Gómez Castellanos, Maximilian J. L. J. Fürst, Marco W. Fraaije, Stefano Rovida
Publikováno v:
eLife
'eLife ', vol: 9, pages: e54639-1-e54639-18 (2020)
eLife, Vol 9 (2020)
eLife, 9:e54639. ELIFE SCIENCES PUBLICATIONS LTD
'eLife ', vol: 9, pages: e54639-1-e54639-18 (2020)
eLife, Vol 9 (2020)
eLife, 9:e54639. ELIFE SCIENCES PUBLICATIONS LTD
Enzyme instability is an important limitation for the investigation and application of enzymes. Therefore, methods to rapidly and effectively improve enzyme stability are highly appealing. In this study we applied a computational method (FRESCO) to g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d31067115ed0717ba25046f0636206
http://europepmc.org/articles/PMC7164962
http://europepmc.org/articles/PMC7164962
Autor:
J. Rubén Gómez Castellanos, Andrea Mattevi, Marco W. Fraaije, Hanna M. Dudek, Maximilian J. L. J. Fürst, Cora Gutiérrez de Souza, Stefano Rovida, Simone Savino
Publikováno v:
Journal of the American Chemical Society, 139(2), 627-630. AMER CHEMICAL SOC
Journal of the American Chemical Society
Journal of the American Chemical Society
Regio- and stereoselective Baeyer-Villiger oxidations are difficult to achieve by classical chemical means, particularly when large, functionalized molecules are to be converted. Biocatalysis using flavin-containing Baeyer-Villiger monooxygenases (BV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc76b5020dcb7d34a6263c9383184e4
https://doi.org/10.1021/jacs.6b12246
https://doi.org/10.1021/jacs.6b12246
Autor:
Erica Elisa Ferrandi, Simone Savino, Sergio Riva, Andrea Mattevi, Stefano Rovida, Federico Forneris, Daniela Monti
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 84:859-865
Hydroxysteroid dehydrogenases are of great interest as biocatalysts for transformations involving steroid substrates. They feature a high degree of stereo- and regio-selectivity, acting on a defined atom with a specific configuration of the steroid n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2323865287e2c73e49994425c07ee83d
https://doi.org/10.1002/prot.25036
https://doi.org/10.1002/prot.25036
Autor:
Stefano Rovida, Giulia Stazi, Paola Dessanti, Veronica Rodriguez, Mario Varasi, Oronza A. Botrugno, Dante Rotili, Antonello Mai, Ciro Mercurio, Andrea Mattevi, Saverio Minucci, Giuseppe Ciossani, Sergio Valente, Alessia Lucidi, Paola Vianello
Publikováno v:
MedChemComm. 6:665-670
On the basis of previous research showing the capability of N-carbobenzyloxy-(Z-)amino acid-tranylcypromine (-TCPA) derivatives to inhibit LSD1, we inserted at the 4-amino-TCPA moiety first a Z-Pro (9) and a Z-Gly (10) residue and then, after the enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca844cf9df35f84de1a28b52aa0b200
https://doi.org/10.1039/c4md00507d
https://doi.org/10.1039/c4md00507d
Autor:
Simone, Savino, Erica Elisa, Ferrandi, Federico, Forneris, Stefano, Rovida, Sergio, Riva, Daniela, Monti, Andrea, Mattevi
Publikováno v:
Proteins. 84(6)
Hydroxysteroid dehydrogenases are of great interest as biocatalysts for transformations involving steroid substrates. They feature a high degree of stereo- and regio-selectivity, acting on a defined atom with a specific configuration of the steroid n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::83b1845030c3dbd5735dc41b9de3a4e9
https://pubmed.ncbi.nlm.nih.gov/27006087
https://pubmed.ncbi.nlm.nih.gov/27006087
Autor:
Stefano Rovida, Ashraf A. Khalil, Dale E. Edmondson, Claudia Binda, Arwa Hammuda, Raed Shalaby
A novel series of substituted chalcones were designed and synthesized to be evaluated as selective human MAO-B inhibitors. A combination of either methylsulfonyl or trifluoromethyl substituents on the aromatic ketone moiety with a benzodioxol ring on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62874c97fd049c1865ab1695a93b25ab
https://hdl.handle.net/10576/22503
https://hdl.handle.net/10576/22503