Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Stefano Pieretti"'
Autor:
Lorenza Marinaccio, Gokhan Zengin, Stefano Pieretti, Paola Minosi, Edina Szucs, Sandor Benyhe, Ettore Novellino, Domiziana Masci, Azzurra Stefanucci, Adriano Mollica
Publikováno v:
Food Chemistry: X, Vol 18, Iss , Pp 100640- (2023)
Rubiscolin-6 (amino acid sequence: YPLDLF) is a selective δ-opioid receptor peptide isolated from spinach Rubisco. Its synthetic analogue, peptide YPMDIV is the most potent described so far for its increased opioid activity, thus in this work it was
Externí odkaz:
https://doaj.org/article/8ae8bcac785b43ffa3acc6337d66acbf
Autor:
Azzurra Stefanucci, Gokhan Zengin, Eulogio J. Llorent-Martinez, Marilisa Pia Dimmito, Alice Della Valle, Stefano Pieretti, Gunes Ak, Kouadio Ibrahime Sinan, Adriano Mollica
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 9, Pp 7078-7086 (2020)
Rutabaga (Brassica napus L.) belonging to Brassicaceae family, is a rich source of polyphenols and glucosinolates. Its consumption in human diet is highly appreciated for its nutritional contribution and health benefits. Brassica napus L. is recogniz
Externí odkaz:
https://doaj.org/article/6a3189ab667246d4a3e467260d627fbc
Autor:
Adriano Mollica, Gokhan Zengin, Kouadio Ibrahime Sinan, Marcella Marletta, Stefano Pieretti, Azzurra Stefanucci, Ouattara Katinan Etienne, József Jekő, Zoltán Cziáky, Mir Babak Bahadori, Carene Picot-Allain, Mohamad Fawzi Mahomoodally
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2171 (2022)
In the quest for novel therapeutic agents from plants, the choice of extraction solvent and technique plays a key role. In this study, the possible differences in the phytochemical profile and bioactivity (antioxidant and enzyme inhibitory activity)
Externí odkaz:
https://doaj.org/article/5697706ec8214a358d6c5f0856f04d88
Autor:
Karol Wtorek, Alessia Ghidini, Luca Gentilucci, Anna Adamska-Bartłomiejczyk, Justyna Piekielna-Ciesielska, Chiara Ruzza, Chiara Sturaro, Girolamo Calò, Stefano Pieretti, Alicja Kluczyk, John McDonald, David G. Lambert, Anna Janecka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12700 (2022)
Recently, mixed opioid/NOP agonists came to the spotlight for their favorable functional profiles and promising outcomes in clinical trials as novel analgesics. This study reports on two novel chimeric peptides incorporating the fragment Tyr-c[D-Lys-
Externí odkaz:
https://doaj.org/article/819627af45404fe79afa47b69584b618
Autor:
Azzurra Stefanucci, Giuseppe Scioli, Lorenza Marinaccio, Gokhan Zengin, Marcello Locatelli, Angela Tartaglia, Alice Della Valle, Angelo Cichelli, Ettore Novellino, Stefano Pieretti, Adriano Mollica
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1474 (2022)
Common bean (Phaseolus vulgaris) represents one of the most famous foods with antiobesity activity showing a significant efficacy against fat accumulation, insulin resistance and dyslipidaemia. In this work, two Italian varieties of common bean, i.e.
Externí odkaz:
https://doaj.org/article/3f939f54bc6a437bae0edafa6f278b50
Autor:
Stefano Pieretti, Anella Saviano, Adriano Mollica, Azzurra Stefanucci, Anna Maria Aloisi, Marcello Nicoletti
Publikováno v:
Molecules, Vol 27, Iss 7, p 2183 (2022)
Phenylpropanoid glycosides are a class of natural substances of plant origin with interesting biological activities and pharmacological properties. This study reports the antinociceptive and anti-inflammatory effects of calceolarioside A, a phenylpro
Externí odkaz:
https://doaj.org/article/275ee404e5ff40e68d531fe83ea5c846
Autor:
Mariantonella Colucci, Azzurra Stefanucci, Adriano Mollica, Anna Maria Aloisi, Francesco Maione, Stefano Pieretti
Publikováno v:
Life, Vol 12, Iss 4, p 500 (2022)
Formyl peptide receptor type 2 (FPR2/ALX) belongs to the formyl peptide receptors (FPRs) family clustered on chromosome 19 and encodes a family of three Class A of G protein-coupled receptors (GPCRs). A short N-terminal region, an NPXXY motif in tran
Externí odkaz:
https://doaj.org/article/53ebae628e0b4ff98a0fb640d60103fb
Autor:
Azzurra Stefanucci, Marilisa Pia Dimmito, Giancarlo Tenore, Stefano Pieretti, Paola Minosi, Gokhan Zengin, Chiara Sturaro, Girolamo Calò, Ettore Novellino, Angelo Cichelli, Adriano Mollica
Publikováno v:
Journal of Functional Foods, Vol 73, Iss , Pp 104154- (2020)
The aim of this work is to investigate the pharmacokinetic properties, antinociceptive and antioxidant activities of rubiscolin-6, soymorphin-6 and their C-terminal amides; The four peptides were synthesized following Fmoc-SPPS strategy to give the f
Externí odkaz:
https://doaj.org/article/ad197431e5a64edfa56ab55cb5f18b75
Autor:
Justyna Piekielna-Ciesielska, Adriano Mollica, Stefano Pieretti, Jakub Fichna, Agata Szymaszkiewicz, Marta Zielińska, Radzisław Kordek, Anna Janecka
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 560-566 (2018)
Opioid peptides and opiate drugs such as morphine, mediate their analgesic effects, but also undesired side effects, mostly through activation of the mu opioid receptor. However, delta- and kappa-opioid receptors can also contribute to the analgesic
Externí odkaz:
https://doaj.org/article/9d8be7976dd248ffb836d7e2a503beb2
Autor:
Azzurra Stefanucci, Giancarlo Tenore, Stefano Pieretti, Paola Minosi, Gokhan Zengin, Chiara Sturaro, Girolamo Calò, Ettore Novellino, Angelo Cichelli, Adriano Mollica
Publikováno v:
Biology and Life Sciences Forum, Vol 6, Iss 1, p 50 (2021)
This study aims to investigate the pharmacokinetic properties, antinociceptive, and antioxidant activities of rubiscolin-6, soymorphin-6, and their C-terminal amides. Rubiscolin-6 and soymorphin-6 are two exhorphins derived from spinach and soybean,
Externí odkaz:
https://doaj.org/article/ed2efabb001649ac9c7c77475cb31dd4