Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Stefano Pagliara"'
Autor:
Samuel Kraus, Megan L Fletcher, Urszula Łapińska, Krina Chawla, Evan Baker, Erin L Attrill, Paul O'Neill, Audrey Farbos, Aaron Jeffries, Edouard E Galyov, Sunee Korbsrisate, Kay B Barnes, Sarah V Harding, Krasimira Tsaneva-Atanasova, Mark A T Blaskovich, Stefano Pagliara
Publikováno v:
PLoS Pathogens, Vol 20, Iss 6, p e1012361 (2024)
The interactions between a virus and its host vary in space and time and are affected by the presence of molecules that alter the physiology of either the host or the virus. Determining the molecular mechanisms at the basis of these interactions is p
Externí odkaz:
https://doaj.org/article/b6c3583e1ed849f4a0d265bd93bc466b
Autor:
Bing Zhang, Wanida Phetsang, M. Rhia L. Stone, Sanjaya Kc, Mark S. Butler, Matthew A. Cooper, Alysha G. Elliott, Urszula Łapińska, Margaritis Voliotis, Krasimira Tsaneva-Atanasova, Stefano Pagliara, Mark A. T. Blaskovich
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Antimicrobial resistance is an urgent threat to human health, and new antibacterial drugs are desperately needed, as are research tools to aid in their discovery and development. Vancomycin is a glycopeptide antibiotic that is widely used fo
Externí odkaz:
https://doaj.org/article/91aa1c2ad9ed465bac7ff7a0422f2845
Autor:
Urszula Łapińska, Georgina Glover, Zehra Kahveci, Nicholas A T Irwin, David S Milner, Maxime Tourte, Sonja-Verena Albers, Alyson E Santoro, Thomas A Richards, Stefano Pagliara
Publikováno v:
PLoS Biology, Vol 21, Iss 4, p e3002048 (2023)
One of the deepest branches in the tree of life separates the Archaea from the Bacteria. These prokaryotic groups have distinct cellular systems including fundamentally different phospholipid membrane bilayers. This dichotomy has been termed the lipi
Externí odkaz:
https://doaj.org/article/8c31bf07a275421d88a842240f1ce28b
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT With the spread of multidrug-resistant bacteria, there has been an increasing focus on molecular classes that have not yet yielded an antibiotic. A key capability for assessing and prescribing new antibacterial treatments is to compare the e
Externí odkaz:
https://doaj.org/article/498f631ebeb443efa590c2d1ff80bad5
Autor:
Georgina Glover, Margaritis Voliotis, Urszula Łapińska, Brandon M. Invergo, Darren Soanes, Paul O’Neill, Karen Moore, Nela Nikolic, Peter G. Petrov, David S. Milner, Sumita Roy, Kate Heesom, Thomas A. Richards, Krasimira Tsaneva-Atanasova, Stefano Pagliara
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
The combined nutritional and salinity limitation is shown to increase glucose uptake and degradation rates in individual E. coli bacteria.
Externí odkaz:
https://doaj.org/article/2cd7bdb833f24378a636ee87d42a81d4
Autor:
Jehangir Cama, Kareem Al Nahas, Marcus Fletcher, Katharine Hammond, Maxim G. Ryadnov, Ulrich F. Keyser, Stefano Pagliara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Antimicrobial resistance challenges the ability of modern medicine to contain infections. Given the dire need for new antimicrobials, polypeptide antibiotics hold particular promise. These agents hit multiple targets in bacteria starting wit
Externí odkaz:
https://doaj.org/article/7d4c17a3d49a4890b5caf90ea541e8d6
Autor:
Sandro Bartolomei, Alessio D’Amico, Filippo Treno, Matteo Cortesi, Stefano Pagliara, Sergio Mignardi
Publikováno v:
Applied Sciences, Vol 13, Iss 20, p 11314 (2023)
The aim of this study was to compare muscle architecture and performance between male and female elite Field Hockey players and to investigate the relationships between echo intensity and performance. Twenty-one male (24.3 ± 3.6 y; 75.1 ± 8.5 kg; 1
Externí odkaz:
https://doaj.org/article/4d271c2ade0c46a5a2478aa8a480535a
Autor:
Rebecca Conners, Mathew McLaren, Urszula Łapińska, Kelly Sanders, M. Rhia L. Stone, Mark A. T. Blaskovich, Stefano Pagliara, Bertram Daum, Jasna Rakonjac, Vicki A. M. Gold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
New virions of Ff bacteriophages are extruded from the host cell via the channel built from phage protein pIV, homologous to bacterial secretins. Here, the authors report the structure of this channel from the f1 filamentous bacteriophage and propose
Externí odkaz:
https://doaj.org/article/f71d9956f4a9496997c3360054dba2c1
Publikováno v:
Open Biology, Vol 12, Iss 7 (2022)
Transporter proteins are a vital interface between cells and their environment. In nutrient-limited environments, microbes with transporters that are effective at bringing substrates into their cells will gain a competitive advantage over variants wi
Externí odkaz:
https://doaj.org/article/2ba9040548514f4daa0a6073b0d53411
Autor:
Urszula Łapińska, Margaritis Voliotis, Ka Kiu Lee, Adrian Campey, M Rhia L Stone, Brandon Tuck, Wanida Phetsang, Bing Zhang, Krasimira Tsaneva-Atanasova, Mark AT Blaskovich, Stefano Pagliara
Publikováno v:
eLife, Vol 11 (2022)
Phenotypic variations between individual microbial cells play a key role in the resistance of microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell individuality in antibiotic accumulation. Here, we hypothesise that pheno
Externí odkaz:
https://doaj.org/article/f9443964bba24775899537b4edeb0b4a