Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stefano Massazza"'
Autor:
Maura Puppo, Annamaria Rapisarda, Zenghui Mi, Stefano Massazza, Sandra Pastorino, Giovanni Melillo, Maria Carla Bosco, Luigi Varesio
Publikováno v:
The Journal of Immunology. 172:1681-1690
Hypoxia, a local decrease in oxygen tension occurring in inflammatory and tumor lesions, modulates gene expression in macrophages. Because macrophages are important chemokine producers, we investigated the regulatory effects of hypoxia on macrophage-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663322eee528833cfff0a5e56554196c
https://doi.org/10.4049/jimmunol.172.3.1681
https://doi.org/10.4049/jimmunol.172.3.1681
Autor:
Luigi Varesio, Stefano Massazza, Sandra Pastorino, Luca Carta, Maria Carla Bosco, Giovanni Melillo
Publikováno v:
Scopus-Elsevier
Activation of murine macrophages (Mφ) requires the collaboration of signals derived from the immune system and the environment. In this study, we engineered a murine Mφ cell line to become activated in response to an environmental signal, hypoxia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f644d83b86f36fc0e66ca1679facc4ef
https://doi.org/10.4049/jimmunol.166.9.5374
https://doi.org/10.4049/jimmunol.166.9.5374
Autor:
Maria Carla Bosco, Stefano Massazza, Luigi Varesio, Giovanni Melillo, Annamaria Rapisarda, Howard A. Young
Publikováno v:
Scopus-Elsevier
We previously found that the tryptophan catabolite picolinic acid (PA) is a costimulus for the activation of macrophage effector functions. In this study, we have investigated the ability of PA to modulate the expression of chemokines in macrophages.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c798689d4ca4d4063b2beebbd52e3f0b
https://doi.org/10.4049/jimmunol.164.6.3283
https://doi.org/10.4049/jimmunol.164.6.3283
Autor:
Maria Carla, Bosco, Annamaria, Rapisarda, Gioia, Reffo, Stefano, Massazza, Sandra, Pastorino, Luigi, Varesio
Publikováno v:
Advances in experimental medicine and biology. 527
Recent studies have suggested a role for aminoacid catabolites as important regulators of macrophage (Mphi) activities. We reported previously that picolinic acid (PA), a tryptophan catabolite produced under inflammatory conditions and a costimulus w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77b23497e82b980cfea59abbe336229d
https://pubmed.ncbi.nlm.nih.gov/15206716
https://pubmed.ncbi.nlm.nih.gov/15206716
Publikováno v:
Cellular immunology. 220(1)
The L-tryptophan catabolite, picolinic acid (PA), is an activator of macrophage effector functions and an inducer of macrophage inflammatory protein-1alpha (MIP-1alpha) and -1beta (MIPs). We have investigated the regulation of PA-induced MIPs product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ed7efe9da55fcfa7549ae0c3587624b
https://pubmed.ncbi.nlm.nih.gov/12718941
https://pubmed.ncbi.nlm.nih.gov/12718941
Autor:
Gioia Reffo, Stefano Massazza, Sandra Pastorino, Annamaria Rapisarda, Maria Carla Bosco, Luigi Varesio
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461349396
Recent studies have suggested a role for aminoacid catabolites as important regulators of macrophage (M4) activities. We reported previously that picolinic acid (PA), a tryptophan catabolite produced under inflammatory conditions and a costimulus wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a817a3923b858aaed49e960aa2d40670
https://doi.org/10.1007/978-1-4615-0135-0_6
https://doi.org/10.1007/978-1-4615-0135-0_6
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 751(1)
A HPLC method is described to quantify picolinic acid in milk, blood serum and tissue culture supernatant. The method requires very little sample preparation because acid precipitation allows total recovery of picolinic acid. High specificity and sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f48ec9c77db05e3d60a1879fac25c
https://pubmed.ncbi.nlm.nih.gov/11232856
https://pubmed.ncbi.nlm.nih.gov/11232856
Publikováno v:
Gene therapy. 8(6)
The goal of this project was to develop a novel gene transfer system based on macrophages (Mphi) as shuttles of recombinant retroviral vectors carrying therapeutic or marker genes. The murine Mphi cell line WGL5 was used as a source of Mphi for this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb53a67fba6ef1bce9264a2c3a782f1
https://pubmed.ncbi.nlm.nih.gov/11313821
https://pubmed.ncbi.nlm.nih.gov/11313821