Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Stefano Gotta"'
Autor:
Giuseppe Pollio, Jeroen J.M. Hoozemans, Claus A. Andersen, Renza Roncarati, Maria Cristina Rosi, Elise S. van Haastert, Tamara Seredenina, Daniela Diamanti, Stefano Gotta, Anna Fiorentini, Letizia Magnoni, Roberto Raggiaschi, Annemieke J.M. Rozemuller, Fiorella Casamenti, Andrea Caricasole, Georg C. Terstappen
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 1, Pp 145-158 (2008)
In a comprehensive proteomics study aiming at the identification of proteins associated with amyloid-beta (Aβ)-mediated toxicity in cultured cortical neurons, we have identified Thimet oligopeptidase (THOP1). Functional modulation of THOP1 levels in
Externí odkaz:
https://doaj.org/article/f395872d345c4193af394d962f5995fb
Autor:
Trina Mouchahoir, John E. Schiel, Rich Rogers, Alan Heckert, Benjamin J. Place, Aaron Ammerman, Xiaoxiao Li, Tom Robinson, Brian Schmidt, Chris M. Chumsae, Xinbi Li, Anton V. Manuilov, Bo Yan, Gregory O. Staples, Da Ren, Alexander J. Veach, Dongdong Wang, Wael Yared, Zoran Sosic, Yan Wang, Li Zang, Anthony M. Leone, Peiran Liu, Richard Ludwig, Li Tao, Wei Wu, Ahmet Cansizoglu, Andrew Hanneman, Greg W. Adams, Irina Perdivara, Hunter Walker, Margo Wilson, Arnd Brandenburg, Nick DeGraan-Weber, Stefano Gotta, Joe Shambaugh, Melissa Alvarez, X. Christopher Yu, Li Cao, Chun Shao, Andrew Mahan, Hirsh Nanda, Kristen Nields, Nancy Nightlinger, Ben Niu, Jihong Wang, Wei Xu, Gabriella Leo, Nunzio Sepe, Yan-Hui Liu, Bhumit A. Patel, Douglas Richardson, Yi Wang, Daniela Tizabi, Oleg V. Borisov, Yali Lu, Ernest L. Maynard, Albrecht Gruhler, Kim F. Haselmann, Thomas N. Krogh, Carsten P. Sönksen, Simon Letarte, Sean Shen, Kristin Boggio, Keith Johnson, Wenqin Ni, Himakshi Patel, David Ripley, Jason C. Rouse, Ying Zhang, Carly Daniels, Andrew Dawdy, Olga Friese, Thomas W. Powers, Justin B. Sperry, Josh Woods, Eric Carlson, K. Ilker Sen, St John Skilton, Michelle Busch, Anders Lund, Martha Stapels, Xu Guo, Sibylle Heidelberger, Harini Kaluarachchi, Sean McCarthy, John Kim, Jing Zhen, Ying Zhou, Sarah Rogstad, Xiaoshi Wang, Jing Fang, Weibin Chen, Ying Qing Yu, John G. Hoogerheide, Rebecca Scott, Hua Yuan
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33:1659-1677
The multi-attribute method (MAM) was conceived as a single assay to potentially replace multiple single-attribute assays that have long been used in process development and quality control (QC) for protein therapeutics. MAM is rooted in traditional p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fbb68de4c53ee4678b9e74066d51588
https://doi.org/10.1021/jasms.2c00129
https://doi.org/10.1021/jasms.2c00129
Autor:
Irina Perdivara, Ben Niu, Kim F. Haselmann, St John Skilton, Anthony Leone, Gregory O. Staples, Carsten P. Sønksen, Helena Maria Barysz, Andrew Hanneman, Chun Shao, Rebecca Scott, Anders Lund, Carly Daniels, Michael Jahn, Da Ren, Nunzio Sepe, K. Ilker Sen, Zoran Sosic, David Ripley, Jing Zhen, Margo Wilson, Melissa Alvarez, John G Hoogerheide, Xinbi Li, Harini Kaluarachchi, Josh Woods, Wenqin Ni, Albrecht Gruhler, Keith A. Johnson, Arnd Brandenburg, Kristen Nields, Michelle Busch, Douglas D. Richardson, Yan Wang, Ahmet Cansizoglu, Xiaoxiao Li, Greg W Adams, Simon Letarte, Joe Shambaugh, Hua Yuan, Trina Mouchahoir, Tom Robinson, Xiaoshi Wang, Nancy S. Nightlinger, Alexander Julian Veach, Chris Chumsae, Eric Carlson, Dongdong Wang, Sean Shen, Jing Fang, Wei Wu, Stefano Gotta, Justin B. Sperry, Hirsh Nanda, X. Christopher Yu, Sibylle Heidelberger, Bhumit A. Patel, Jihong Wang, Sean McCarthy, Himakshi Patel, Thomas N. Krogh, Hunter Walker, Olga V. Friese, Daniela Tizabi, Yali Lu, Kristin Boggio, Ernest L. Maynard, Rich Rogers, Ying Zhou, Nick DeGraan-Weber, John E. Schiel, Weibin Chen, Jason C. Rouse, Li Tao, Thomas W. Powers, John Kim, Xu Guo, Bo Yan, Gabriella Leo, Ying Zhang, Oleg V. Borisov, Ying Qing Yu, Martha Stapels, Wael Yared, Yan-Hui Liu, Alan Heckert, Sarah Rogstad, Li Zang, Aaron Ammerman, Li Cao, Benjamin J. Place, Richard Ludwig, Anton V. Manuilov, Andrew Mahan, Andrew Dawdy, Yi Wang, Brian Schmidt, Peiran Liu
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:913-928
The Multi-Attribute Method (MAM) Consortium was initially formed as a venue to harmonize best practices, share experiences, and generate innovative methodologies to facilitate widespread integration of the MAM platform, which is an emerging ultra-hig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4baf4a0ab2df01bdb011465e0f168239
https://doi.org/10.1021/jasms.0c00415
https://doi.org/10.1021/jasms.0c00415
Autor:
Ramona Nudischer, Hans Gmuender, Ralf Herwig, Nathalie Selevsek, Olivia Clayton, Jos C. S. Kleinjans, Marcha Verheijen, Matthias Lienhard, Florian Caiment, Joep P.M. Geraedts, Stefano Gotta, Yannick Schrooders, Ralph Schlapbach, Bernd Timmermann, Stefan Boerno
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 9:4641, 1-12. Nature Publishing Group
Scientific Reports, 9
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, 9:4641, 1-12. Nature Publishing Group
Scientific Reports, 9
Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity in the 1960s, later, the FDA classified DMSO in the safest solvent category. DMSO became widely used in many biomedical fields and biological effects were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1802fafe7f78561a9e076aa76948b56a
https://doi.org/10.1038/s41598-019-40660-0
https://doi.org/10.1038/s41598-019-40660-0
Publikováno v:
Bioconjugate chemistry. 29(5)
Invasive nontyphoidal Salmonella disease, for which licensed vaccines are not available, is a leading cause of bloodstream infections in Africa. The O-antigen portion of lipopolysaccharide is a good target for protective immunity. Covalent conjugatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ed46584bd0d4d6b1b6292881dd9c0b
https://pubmed.ncbi.nlm.nih.gov/29697244
https://pubmed.ncbi.nlm.nih.gov/29697244
Autor:
Bernd Timmermann, Ralph Schlapbach, Hans Gmuender, Stefano Gotta, Marcha Verheijen, Matthias Lienhard, Florian Caiment, Stefan Boerno, Yannick Schrooders, O. Clayton, Ramona Nudischer, Ralf Herwig, J.C.S. Kleinjans, N. Selevsek
Publikováno v:
TOXICOLOGY LETTERS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1150ec29843c198cc6c46d75cd4641
https://doi.org/10.1016/j.toxlet.2018.06.927
https://doi.org/10.1016/j.toxlet.2018.06.927
Autor:
Susanna Pennacchini, Georg C. Terstappen, Stefano Gotta, Marina Rocchigiani, Francesco Neri, Maurizio Orlandini, Gian Luca Sardone, Felice Petraglia, Ahmad Salameh, Giacomo Matteucci, Federico Galvagni, Salvatore Oliviero
Publikováno v:
Circulation Research. 106:1839-1848
Rationale : Integrins cooperate with growth factor receptors to promote downstream signaling for cell proliferation and migration. However, the mechanism of receptor activation is still unknown. Objective : To analyze the mechanism of phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0de377b79de437d28e6206226e21fca3
https://doi.org/10.1161/circresaha.109.206326
https://doi.org/10.1161/circresaha.109.206326
Autor:
Renza Roncarati, Andrea Caricasole, Anna Fiorentini, Stefano Gotta, Roberto Raggiaschi, Georg C. Terstappen, Letizia Magnoni, Jeroen J.M. Hoozemans, Giuseppe Pollio, Tamara Seredenina, Daniela Diamanti, Elise S. van Haastert, Annemieke J.M. Rozemuller, Claus A. Andersen, Maria Cristina Rosi, Fiorella Casamenti
Publikováno v:
Neurobiology of Disease, Vol 31, Iss 1, Pp 145-158 (2008)
Pollio, G, Hoozemans, J J M, Andersen, C A, Roncarati, R, Rosi, M C, van Haastert, E S, Seredenina, T, Diamanti, D, Gotta, S, Fiorentini, A, Magnoni, L, Raggiaschi, R, Rozemuller, A J M, Casamenti, F, Caricasole, A & Terstappen, G C 2008, ' Increased expression of the oligopeptidase THOP1 is a neuroprotective response to A beta toxicity ', Neurobiology of Disease, vol. 31, no. 1, pp. 145-158 . https://doi.org/10.1016/j.nbd.2008.04.004
Neurobiology of Disease, 31(1), 145-158. Academic Press Inc.
Pollio, G, Hoozemans, J J M, Andersen, C A, Roncarati, R, Rosi, M C, van Haastert, E S, Seredenina, T, Diamanti, D, Gotta, S, Fiorentini, A, Magnoni, L, Raggiaschi, R, Rozemuller, A J M, Casamenti, F, Caricasole, A & Terstappen, G C 2008, ' Increased expression of the oligopeptidase THOP1 is a neuroprotective response to A beta toxicity ', Neurobiology of Disease, vol. 31, no. 1, pp. 145-158 . https://doi.org/10.1016/j.nbd.2008.04.004
Neurobiology of Disease, 31(1), 145-158. Academic Press Inc.
In a comprehensive proteomics study aiming at the identification of proteins associated with amyloid-beta (Abeta)-mediated toxicity in cultured cortical neurons, we have identified Thimet oligopeptidase (THOP1). Functional modulation of THOP1 levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c110ec09431d10d89afae578124d1b
http://www.sciencedirect.com/science/article/pii/S0969996108000740
http://www.sciencedirect.com/science/article/pii/S0969996108000740
Autor:
Letizia Magnoni, Roberto Raggiaschi, Georg C. Terstappen, Stefano Gotta, Simonetta Bernocco, Silvia Matteoni, Costanza Fondelli
Publikováno v:
PROTEOMICS. 8:930-938
Proteomics studies employing primary neurons are difficult due to the neurons' characteristics. We have developed a detergent-based fractionation method which reduces complexity of the protein extracts, is sufficiently fast to allow differential prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5849161e2f53a671559ad3f1d02ea822
https://doi.org/10.1002/pmic.200700738
https://doi.org/10.1002/pmic.200700738
Autor:
Andreas Kremer, Georg C. Terstappen, Roberto Raggiaschi, Claus A. Andersen, Letizia Magnoni, Stefano Gotta
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 10, Iss 1, p 141 (2009)
BMC Bioinformatics, Vol 10, Iss 1, p 141 (2009)
Background Quantitative measurements of specific protein phosphorylation sites, as presented here, can be used to investigate signal transduction pathways, which is an important aspect of cell dynamics. The presented method quantitatively compares pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04cd7cdee7e97eb85164688b9fc4cba9
https://doi.org/10.1186/1471-2105-10-141
https://doi.org/10.1186/1471-2105-10-141