Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stefano F. Liparoto"'
Publikováno v:
Journal of Immunological Methods. 390:9-17
Phagocytosis plays a pivotal and essential role in host immune defense, both as a focal constituent of the innate immune response and a bridging element linking innate and adaptive immunity. Phagocytosis has been demonstrated to be critical in develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43325ec52eb9cbb83fdf4687b5f1fd46
https://doi.org/10.1016/j.jim.2011.06.027
https://doi.org/10.1016/j.jim.2011.06.027
Autor:
Michael J. Nemeth, Zining Wu, Thomas M. Laue, Thomas L. Ciardelli, Byron Goldstein, Stefano F. Liparoto
Publikováno v:
Protein Science. 8:482-489
The high affinity interleukin-2 receptor is composed of three cell surface subunits, IL-2Ralpha, IL-2Rbeta, and IL-2Rgamma. Functional forms of the IL-2 receptor exist, however, that enlist only two of the three subunits. On activated T-cells, the al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc374fe03a4155056b56d14291545fef
https://doi.org/10.1110/ps.8.3.482
https://doi.org/10.1110/ps.8.3.482
Autor:
Stefano F. Liparoto, John Eldredge, You Li, Christopher Fitch, Mia Rushe, Alexey Lugovskoy, Karl J. M. Hanf, Matthew Jarpe, Herman W. T. van Vlijmen, Woody Sherman, Kenneth Simon, Louis A. Clark, P. Ann Boriack-Sjodin, Miller Stephan S, Bethany Friedman
Publikováno v:
Protein Science. 15:949-960
Improving the affinity of a high-affinity protein-protein interaction is a challenging problem that has practical applications in the development of therapeutic biomolecules. We used a combination of structure-based computational methods to optimize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e85270373cb16f8b1af9a0192a5a136
https://doi.org/10.1110/ps.052030506
https://doi.org/10.1110/ps.052030506
Autor:
Stefano F. Liparoto, Melanie Wong, Eric S. Day, Michael Sekar, Donald B. Bennett, Michelle J. Cannon, Dave Casper, Edward J. Collins, Susanne Nyholm Westin, Inna Gorshkova, Yue Jin Li, Karen M. Worthy, Amy Neurauter, Daulet Satpaev, Gerardo R. Marchesini, Paul J. Cachia, Teresa Chu, Ryan James Darling, Jack Simpson, Daniel Kao, Dax A. Rice, Karlicek Shannon Marie, Robert J. Fisher, Magdalena Bynum, Michael Swanson, David G. Myszka, Eric D. Sullivan, Dianne Hodges, Lindsey R. Roberts, Amy M. Liang, Ashique Rafique, Huawei Qiu, Andrew G. Stephen, Giuseppe A. Papalia, Iva Navratilova, Eric Hommema, Béatrice Luginbühl, Jean Inman, Stephen J. Ullrich
Publikováno v:
Analytical Biochemistry 330 (2004) 1
Analytical Biochemistry, 330(1), 98-113
Analytical Biochemistry, 330(1), 98-113
To gauge the experimental variability associated with Biacore analysis, 36 different investigators analyzed a small molecule/enzyme interaction under similar conditions. Acetazolamide (222 g/mol) binding to carbonic anhydrase II (CAII; 30,000 Da) was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f902d2fc2f47b9116e87905fdebf021
https://doi.org/10.1016/j.ab.2004.02.027
https://doi.org/10.1016/j.ab.2004.02.027
Autor:
Zining Wu, Thomas M. Laue, Stefano F. Liparoto, Thomas L. Ciardelli, Byron Goldstein, David G. Myszka
Publikováno v:
Biochemistry. 41:2543-2551
Interleukin-2 is the primary T cell growth factor secreted by activated T cells. IL-2 is an alpha-helical cytokine that binds to a multisubunit receptor expressed on the surface of a variety of cell types. IL-2Ralpha, IL-2Rbeta, and IL-2Rgammac recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d58a6de78a9a54ccaa0f374947fa6a5
https://doi.org/10.1021/bi011692m
https://doi.org/10.1021/bi011692m
Autor:
Douglas A. Lauffenburger, Stefano F. Liparoto, Eric M. Fallon, Kathy J. Lee, Thomas L. Ciardelli
Publikováno v:
Journal of Biological Chemistry. 275:6790-6797
An interleukin-2 (IL-2) variant containing adjacent point mutations (L18M/L19S, termed 2D1) displaying binding affinity to the heterotrimeric IL-2 receptor similar to that of wild-type IL-2 (WT) had been previously found to surprisingly exhibit incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9171f0aa0ed095ed4851cec8406921aa
https://doi.org/10.1074/jbc.275.10.6790
https://doi.org/10.1074/jbc.275.10.6790
Publikováno v:
Journal of Molecular Recognition. 12:316-321
Surface plasmon resonance (SPR) biosensor technology has been a significant addition to the evolution and refinement of methods to study macromolecular interactions. Prior to the advent of SPR, we employed a variety of biochemical and biological tech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315b29b2450eb460332cce500853752d
https://doi.org/10.1002/(sici)1099-1352(199909/10)12:5<316::aid-jmr468>3.0.co
https://doi.org/10.1002/(sici)1099-1352(199909/10)12:5<316::aid-jmr468>3.0.co