Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Stefano Duga"'
Autor:
Chiara Chiereghin, Michela Robusto, Morag A Lewis, Susana Caetano, Valentina Massa, Pierangela Castorina, Umberto Ambrosetti, Karen P Steel, Stefano Duga, Rosanna Asselta, Giulia Soldà
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0273586 (2023)
Diaphanous related formins are regulatory cytoskeletal protein involved in actin elongation and microtubule stabilization. In humans, defects in two of the three diaphanous genes (DIAPH1 and DIAPH3) have been associated with different types of hearin
Externí odkaz:
https://doaj.org/article/ccb3ac33f03a448097cb557fcb46ae43
Autor:
Monica Zuradelli, Massimo Lazzeri, Egesta Lopci, Paolo Andrea Zucali, Luca Balzarini, Giorgio Guazzoni, Piergiuseppe Colombo, Marta Scorsetti, Ciro Franzese, Rosanna Asselta, Giulia Soldà, Stefano Duga
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-4 (2021)
Hippocrates (Kos, c.460–c.370 BC) reminds us that “It is more important to know what sort of person has a disease than to know what sort of disease a person has”. This is still true today and reflects the emerging role of personalized medicine
Externí odkaz:
https://doaj.org/article/519b98d194d943a496e128425d596a58
Autor:
Maddalena Ardissino, Adam J. Nelson, Giuseppe Maglietta, Guidantonio Malagoli Tagliazucchi, Caterina Disisto, Patrizia Celli, Maurizio Ferrario, Umberto Canosi, Carlo Cernetti, Francesco Negri, Piera Angelica Merlini, Marco Tubaro, Carlo Berzuini, Chiara Manzalini, Gianfranco Ignone, Carlo Campana, Luigi Moschini, Elisabetta Ponte, Roberto Pozzi, Raffaela Fetiveau, Silvia Buratti, Elvezia Maria Paraboschi, Rosanna Asselta, Andrea Botti, Domenico Tuttolomondo, Federico Barocelli, Serena Bricoli, Andrea Biagi, Rosario Bonura, Tiziano Moccetti, Antonio Crocamo, Giorgio Benatti, Giorgia Paoli, Emilia Solinas, Maria Francesca Notarangelo, Elisabetta Moscarella, Paolo Calabrò, Stefano Duga, Giulia Magnani, Diego Ardissino
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
ImportanceThere is growing awareness of sex-related differences in cardiovascular risk profiles, but less is known about whether these extend to pre-menopausal females experiencing an early-onset myocardial infarction (MI), who may benefit from the p
Externí odkaz:
https://doaj.org/article/885a407af86a408785d5d23d7618d5e0
Autor:
Cesare Saitta, Ilaria De Simone, Vittorio Fasulo, Marinella Corbetta, Stefano Duga, Chiara Chiereghin, Federico Simone Colombo, Alessio Benetti, Roberto Contieri, Pier Paolo Avolio, Alessandro Uleri, Alberto Saita, Giorgio Ferruccio Guazzoni, Rodolfo Hurle, Piergiuseppe Colombo, Nicolò Maria Buffi, Paolo Casale, Giovanni Lughezzani, Rosanna Asselta, Giulia Soldà, Massimo Lazzeri
Publikováno v:
Cancers, Vol 15, Iss 10, p 2666 (2023)
Liquid biopsy (LB) for prostate cancer (PCa) detection could represent an alternative to biopsy. Seminal fluid (SF) is a source of PCa-specific biomarkers, as 40% of ejaculate derives from the prostate. We tested the feasibility of an SF-based LB by
Externí odkaz:
https://doaj.org/article/aa9a7bcdf0364af084ada4d670b421a2
Autor:
Rosanna Asselta, Luca Di Tommaso, Matteo Perrino, Annarita Destro, Laura Giordano, Giulia Cardamone, Luca Rubino, Armando Santoro, Stefano Duga, Paolo Andrea Zucali
Publikováno v:
Thoracic Cancer, Vol 12, Iss 9, Pp 1271-1278 (2021)
Abstract Background Significant efforts have been made to investigate the molecular pathways involved in thymic carcinogenesis. However, genetic findings have still not impacted clinical practice. The aim of this exploratory trial was to evaluate the
Externí odkaz:
https://doaj.org/article/c2022b72fe96420191f30f8582e0a660
Autor:
Marianna Paulis, Lucia Susani, Alessandra Castelli, Teruhiko Suzuki, Takahiko Hara, Letizia Straniero, Stefano Duga, Dario Strina, Stefano Mantero, Elena Caldana, Lucia Sergi Sergi, Anna Villa, Paolo Vezzoni
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 369-377 (2020)
Many human genetic diseases are associated with gross mutations such as aneuploidies, deletions, duplications, or inversions. For these “structural” disorders, conventional gene therapy, based on viral vectors and/or on programmable nuclease-medi
Externí odkaz:
https://doaj.org/article/cafafd205a104ab4b7eb5032e65b38ea
Autor:
Matteo Vecellio, Elvezia Maria Paraboschi, Angela Ceribelli, Natasa Isailovic, Francesca Motta, Giulia Cardamone, Michela Robusto, Rosanna Asselta, Sonia Brescianini, Francesco Sacrini, Antonio Costanzo, Maria De Santis, Maria Antonietta Stazi, Stefano Duga, Carlo Selmi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Background: Psoriatic disease is a multifactorial inflammatory condition spanning from skin and nail psoriasis (Pso) to spine and joint involvement characterizing psoriatic arthritis (PsA). Monozygotic twins provide a model to investigate genetic, ea
Externí odkaz:
https://doaj.org/article/67ddcebb3dfb4d62a5b99a030787d91e
Autor:
Giulia Lunghi, Emma Veronica Carsana, Nicoletta Loberto, Laura Cioccarelli, Simona Prioni, Laura Mauri, Rosaria Bassi, Stefano Duga, Letizia Straniero, Rosanna Asselta, Giulia Soldà, Alessio Di Fonzo, Emanuele Frattini, Manuela Magni, Nara Liessi, Andrea Armirotti, Elena Ferrari, Maura Samarani, Massimo Aureli
Publikováno v:
Cells, Vol 11, Iss 15, p 2343 (2022)
β-glucocerebrosidase is a lysosomal hydrolase involved in the catabolism of the sphingolipid glucosylceramide. Biallelic loss of function mutations in this enzyme are responsible for the onset of Gaucher disease, while monoallelic β-glucocerebrosid
Externí odkaz:
https://doaj.org/article/0c02205b205142f68964b014a1490b02
Post-Biopsy Cell-Free DNA From Blood: An Open Window on Primary Prostate Cancer Genetics and Biology
Autor:
Marinella Corbetta, Chiara Chiereghin, Ilaria De Simone, Giulia Soldà, Monica Zuradelli, Michele Giunta, Giovanni Lughezzani, Nicolò Maria Buffi, Rodolfo Hurle, Alberto Saita, Paolo Casale, Rosanna Asselta, Massimo Lazzeri, Giorgio Guazzoni, Stefano Duga
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Circulating cell-free DNA (ccfDNA), released from normal and cancerous cells, is a promising biomarker for cancer detection as in neoplastic patients it is enriched in tumor-derived DNA (ctDNA). ctDNA contains cancer-specific mutations and epigenetic
Externí odkaz:
https://doaj.org/article/b6cb2ee55027498b9005d382140b1ea2
Autor:
Chiara Chiereghin, Michela Robusto, Lucia Mauri, Paola Primignani, Pierangela Castorina, Umberto Ambrosetti, Stefano Duga, Rosanna Asselta, Giulia Soldà
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Inherited hearing loss is extremely heterogeneous both clinically and genetically. In addition, the spectrum of deafness-causing genetic variants differs greatly among geographical areas and ethnicities. The identification of the causal mutation in a
Externí odkaz:
https://doaj.org/article/258f7bde931445eb9453f326690476f2