Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Stefano Ciciliot"'
Autor:
Francesca Gasparella, Leonardo Nogara, Elena Germinario, Lucia Tibaudo, Stefano Ciciliot, Giorgia Piccoli, Francisca Carolina Venegas, Francesca Fontana, Gabriele Sales, Daniele Sabbatini, Jonathan Foot, Wolfgang Jarolimek, Bert Blaauw, Marcella Canton, Libero Vitiello
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 622 (2024)
Duchenne muscular dystrophy (DMD) is one of the most frequent and severe childhood muscle diseases. Its pathophysiology is multifaceted and still incompletely understood, but we and others have previously shown that oxidative stress plays an importan
Externí odkaz:
https://doaj.org/article/eb4d41f94e05471da372e53099a39cb6
Autor:
Caterina Tezze, Francesco Ivan Amendolagine, Leonardo Nogara, Martina Baraldo, Stefano Ciciliot, Diletta Arcidiacono, Alice Zaramella, Giulio Masiero, Giulia Ferrarese, Stefano Realdon, Bert Blaauw, Giel Detienne, Ann T.J. Beliën, Marco Sandri, Evi M. Mercken
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Age-associated sarcopenia, characterized by a progressive loss in muscle mass and strength, is the largest cause of frailty and disability in the elderly worldwide. Current treatments involve nonpharmacological guidelines that few subjects can abide
Externí odkaz:
https://doaj.org/article/09918d7a9d09464da143c0f003e670fe
Autor:
Laura Giurgola, Claudio Gatto, Diego Ponzin, Stefano Ferrari, Eugenio Ragazzi, Orietta Rossi, Lorenzo Bosio, Jana D’amato Tothova, Umberto Rodella, Stefano Ciciliot
Publikováno v:
BMJ Open Ophthalmology, Vol 8, Iss Suppl 2 (2023)
Externí odkaz:
https://doaj.org/article/0177d4c012f44983a8bf02ab29b2879a
Autor:
Alessia Geremia, Roberta Sartori, Martina Baraldo, Leonardo Nogara, Valeria Balmaceda, Georgia Ana Dumitras, Stefano Ciciliot, Marco Scalabrin, Hendrik Nolte, Bert Blaauw
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 1, Pp 648-661 (2022)
Abstract Background Cancer‐related muscle wasting occurs in most cancer patients. An important regulator of adult muscle mass and function is the Akt–mTORC1 pathway. While Akt–mTORC1 signalling is important for adult muscle homeostasis, it is a
Externí odkaz:
https://doaj.org/article/f2c5ee8dc9fe47e5ae7ab52b380b8686
Autor:
Marta Murgia, Luana Toniolo, Nagarjuna Nagaraj, Stefano Ciciliot, Vincenzo Vindigni, Stefano Schiaffino, Carlo Reggiani, Matthias Mann
Publikováno v:
Cell Reports, Vol 19, Iss 11, Pp 2396-2409 (2017)
Skeletal muscle is a key tissue in human aging, which affects different muscle fiber types unequally. We developed a highly sensitive single muscle fiber proteomics workflow to study human aging and show that the senescence of slow and fast muscle fi
Externí odkaz:
https://doaj.org/article/4fdadd7514f2456fb0ef21aece3ce9a6
Autor:
Irene Moretti, Stefano Ciciliot, Kenneth A. Dyar, Reimar Abraham, Marta Murgia, Lisa Agatea, Takayuki Akimoto, Silvio Bicciato, Mattia Forcato, Philippe Pierre, N. Henriette Uhlenhaut, Peter W. J. Rigby, Jaime J. Carvajal, Bert Blaauw, Elisa Calabria, Stefano Schiaffino
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Mrf4 is a transcription factor important for muscle development, but despite high expression its function in adults is unknown. Here the authors show that interfering with Mrf4 in adult mice leads to muscle hypertrophy by activating MEF2-dependent tr
Externí odkaz:
https://doaj.org/article/9baf8edc4e774e3bbf5c7edc3c424c25
Autor:
Kenneth Allen Dyar, Michaël Jean Hubert, Ashfaq Ali Mir, Stefano Ciciliot, Dominik Lutter, Franziska Greulich, Fabiana Quagliarini, Maximilian Kleinert, Katrin Fischer, Thomas Oliver Eichmann, Lauren Emily Wright, Marcia Ivonne Peña Paz, Alberto Casarin, Vanessa Pertegato, Vanina Romanello, Mattia Albiero, Sara Mazzucco, Rosario Rizzuto, Leonardo Salviati, Gianni Biolo, Bert Blaauw, Stefano Schiaffino, N Henriette Uhlenhaut
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2005886 (2018)
Circadian clocks are fundamental physiological regulators of energy homeostasis, but direct transcriptional targets of the muscle clock machinery are unknown. To understand how the muscle clock directs rhythmic metabolism, we determined genome-wide b
Externí odkaz:
https://doaj.org/article/2baff020749c46b7943454ca2b934a95
Autor:
Kenneth A. Dyar, Stefano Ciciliot, Guidantonio Malagoli Tagliazucchi, Giorgia Pallafacchina, Jana Tothova, Carla Argentini, Lisa Agatea, Reimar Abraham, Miika Ahdesmäki, Mattia Forcato, Silvio Bicciato, Stefano Schiaffino, Bert Blaauw
Publikováno v:
Molecular Metabolism, Vol 4, Iss 11, Pp 823-833 (2015)
Objective: Physical activity and circadian rhythms are well-established determinants of human health and disease, but the relationship between muscle activity and the circadian regulation of muscle genes is a relatively new area of research. It is un
Externí odkaz:
https://doaj.org/article/94a4f9d7ddf34a4f8286ec1858fca271
Autor:
Guido Gambara, Michele Salanova, Stefano Ciciliot, Sandra Furlan, Martina Gutsmann, Gudrun Schiffl, Ute Ungethuem, Pompeo Volpe, Hanns-Christian Gunga, Dieter Blottner
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of the molecular changes in human or mouse paraspinal mus
Externí odkaz:
https://doaj.org/article/439bb6895f46473480744b2ae2b3d245
Autor:
Guido Gambara, Michele Salanova, Stefano Ciciliot, Sandra Furlan, Martina Gutsmann, Gudrun Schiffl, Ute Ungethuem, Pompeo Volpe, Hanns-Christian Gunga, Dieter Blottner
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169314 (2017)
Microgravity exposure as well as chronic disuse are two main causes of skeletal muscle atrophy in animals and humans. The antigravity calf soleus is a reference postural muscle to investigate the mechanism of disuse-induced maladaptation and plastici
Externí odkaz:
https://doaj.org/article/be27e9c38d2a4bc7bca1eb6be6657af7