Výsledky vyhledávání - "Stefano Caserta"

Akademický článek

Bruton’s Tyrosine Kinase Inhibitors Impair FcγRIIA-Driven Platelet Responses to Bacteria in Chronic Lymphocytic Leukemia

Autor: Leigh Naylor-Adamson, Anisha R. Chacko, Zoe Booth, Stefano Caserta, Jenna Jarvis, Sujoy Khan, Simon P. Hart, Francisco Rivero, David J. Allsup, Mònica Arman

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Bacterial infections are a major cause of morbidity and mortality in chronic lymphocytic leukemia (CLL), and infection risk increases in patients treated with the Bruton’s tyrosine kinase (Btk) inhibitor, ibrutinib. Btk and related kinases (like Te

Externí odkaz: https://doaj.org/article/ae5be3bf207c4bf3ac689a97a416281c

Zobrazit plný text záznamu

Akademický článek

In-Depth Profiling of T-Cell Responsiveness to Commonly Recognized CMV Antigens in Older People Reveals Important Sex Differences

Autor: Bernhard Reus, Stefano Caserta, Martin Larsen, George Morrow, Aalia Bano, Michael Hallensleben, Chakravarthi Rajkumar, Alejandra Pera, Florian Kern

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

The impact of biological sex on T-cell immunity to Cytomegalovirus (CMV) has not been investigated in detail with only one published study comparing CMV-specific T-cell responses in men and women. Many studies, however, have shown an association betw

Externí odkaz: https://doaj.org/article/b951e00c673f46a0b439906d827a99e9

Zobrazit plný text záznamu

Akademický článek

Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs

Autor: Stefano Caserta, Manuela Mengozzi, Florian Kern, Sarah F. Newbury, Pietro Ghezzi, Martin J. Llewelyn

Publikováno v: Frontiers in Immunology, Vol 8 (2018)

The systemic inflammatory response syndrome (SIRS) is a potentially lethal response triggered by diverse forms of tissue injury and infection. When systemic inflammation is triggered by infection, the term sepsis is used. Understanding how inflammati

Externí odkaz: https://doaj.org/article/af2a0232dd1648d7914b7ecb943939bb

Zobrazit plný text záznamu

Akademický článek

Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells

Autor: David Gray, Marta Trüb, Tom A. Barr, Vicky L. Morrison, Sheila Brown, Stefano Caserta, Jordan Rixon, Alasdair Ivens

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

T follicular helper cells (Tfh) provide crucial signals for germinal center (GC) formation, but Tfh populations are heterogeneous. While PD1hi Tfh are important in the GC response, the function of the PD1lo Tfh-like subset is unknown. We show that th

Externí odkaz: https://doaj.org/article/1fa61be064b6496ba2d3deb7e80e0c18

Zobrazit plný text záznamu

Akademický článek

Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells.

Autor: Stefano Caserta, Norman Nausch, Amy Sawtell, Rebecca Drummond, Tom Barr, Andrew S Macdonald, Francisca Mutapi, Rose Zamoyska

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35466 (2012)

Certain parasites have evolved to evade the immune response and establish chronic infections that may persist for many years. T cell responses in these conditions become muted despite ongoing infection. Upregulation of surface receptors with inhibito

Externí odkaz: https://doaj.org/article/345b9478c1014c4db3d8a4eb99488617

Zobrazit plný text záznamu

Bruton’s Tyrosine Kinase Inhibitors Impair FcγRIIA-Driven Platelet Responses to Bacteria in Chronic Lymphocytic Leukemia

Autor: Zoe Booth, Leigh Naylor-Adamson, Simon P. Hart, Stefano Caserta, David Allsup, Sujoy Khan, Anisha R. Chacko, Jenna Jarvis, Francisco Rivero, Mònica Arman

Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f8e5242dcffe58612e48f19f7701552
https://www.frontiersin.org/articles/10.3389/fimmu.2021.766272/full

Zobrazit plný text záznamu

Release of redox enzymes and micro-RNAs in extracellular vesicles, during infection and inflammation

Autor: Stefano Caserta, Pietro Ghezzi

Many studies reported that redox enzymes, particularly thioredoxin and peroxiredoxin, can be released by cells and act as soluble mediators in immunity. Recently, it became clear that peroxiredoxins can be secreted via the exosome-release route, yet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1a9619324c2a20bb5b0880d723d26e
http://sro.sussex.ac.uk/id/eprint/98442/1/CasertaGhezzi_R1.pdf

Zobrazit plný text záznamu

Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells

Autor: Stefano Caserta, Kevin A. Davies, Florian Kern, Aalia S. Bano, Chakravarthi Rajkumar, Helen Smith, Bernhard Reus, Frances A. Kirkham, Alejandra Pera, Amanda M. Simanek, George Morrow

Publikováno v: Theranostics

Human Cytomegalovirus (CMV) infection is associated with atherosclerosis, higher cardiovascular disease (CVD) risk, and an increase in memory T-cells (Tmem). T-cells have also been implicated in CVD, independently of CMV infection. To better understa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3771cad75a935967de28694c3e21847d

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání