Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Stefano Cardinale"'
Autor:
Stefano Cardinale, Haja N. Kadarmideen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Cattle production is one of the key contributors to global warming due to methane emission, which is a by-product of converting feed stuff into milk and meat for human consumption. Rumen hosts numerous microbial communities that are involved in the d
Externí odkaz:
https://doaj.org/article/097ceafd74d64aacbdc54cf6864a9708
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1029-1037 (2017)
Summary: Production of chemicals in microbes often employs potent biosynthetic enzymes, which can interact with the microbial native metabolism to affect cell fitness and product yield. However, production optimization largely relies on data collecte
Externí odkaz:
https://doaj.org/article/920bca155c7f42ff84c0520c926b9169
Publikováno v:
Cell Reports, Vol 4, Iss 2, Pp 231-237 (2013)
Predictable operation of engineered biological circuitry requires the knowledge of host factors that compete or interfere with designed function. Here, we perform a detailed analysis of the interaction between constitutive expression from a test circ
Externí odkaz:
https://doaj.org/article/0ffc964542464b7a86cc8b97d5e55763
Autor:
Guillaume Cambray, Stefano Cardinale
Publikováno v:
BMC Systems Biology, Vol 11, Iss 1, Pp 1-8 (2017)
BMC Systems Biology
BMC Systems Biology, BioMed Central, 2017, 11 (1), 8 p. ⟨10.1186/s12918-017-0494-1⟩
Cardinale, S & Cambray, G 2017, ' Genome-wide analysis of E. coli cell-gene interactions ', BMC Systems Biology, vol. 11, no. 1, 112 . https://doi.org/10.1186/s12918-017-0494-1
BMC Systems Biology 1 (11), 8 p.. (2017)
BMC Systems Biology
BMC Systems Biology, BioMed Central, 2017, 11 (1), 8 p. ⟨10.1186/s12918-017-0494-1⟩
Cardinale, S & Cambray, G 2017, ' Genome-wide analysis of E. coli cell-gene interactions ', BMC Systems Biology, vol. 11, no. 1, 112 . https://doi.org/10.1186/s12918-017-0494-1
BMC Systems Biology 1 (11), 8 p.. (2017)
Background The pursuit of standardization and reliability in synthetic biology has achieved, in recent years, a number of advances in the design of more predictable genetic parts for biological circuits. However, even with the development of high-thr
Autor:
Stefano Cardinale
The study presents an analysis of how different cellular functions link cell size to the expression of synthetic genes inE. coli. The Size-Expression interaction was mapped with a two-gene genetic probe across 3800 single-gene deletion strains. Throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2496b43f1a7ca570368b372b5b7e24c6
Publikováno v:
Cardinale, S, Ye, L & Sommer, M O A 2016, ' An Integrated Genomics Framework for System-Level Cell Factory Design ', An Integrated Genomics Framework for System-Level Cell Factory Design, Milano, Italy, 22/02/2016-22/02/2016 .
Technical University of Denmark Orbit
Technical University of Denmark Orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2ef5b5b1100ad57a883995adac9f5fa8
https://orbit.dtu.dk/en/publications/04075a01-8030-4813-96de-1635fa6a5d50
https://orbit.dtu.dk/en/publications/04075a01-8030-4813-96de-1635fa6a5d50
Autor:
Hiroshi Masumoto, Stefano Cardinale, Reto Gassmann, Paola Vagnarelli, Stefanie Kandels-Lewis, Megumi Nakano, William C. Earnshaw, Vladimir Larionov, Vladimir N. Noskov
Publikováno v:
Developmental Cell
Nakano, M, Cardinale, S, Noskov, V N, Gassmann, R, Vagnarelli, P, Kandels-Lewis, S, Larionov, V, Earnshaw, W C & Masumoto, H 2008, ' Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers ', Developmental Cell, vol. 14, no. 4, pp. 507-522 . https://doi.org/10.1016/j.devcel.2008.02.001
Nakano, M, Cardinale, S, Noskov, V N, Gassmann, R, Vagnarelli, P, Kandels-Lewis, S, Larionov, V, Earnshaw, W C & Masumoto, H 2008, ' Inactivation of a Human Kinetochore by Specific Targeting of Chromatin Modifiers ', Developmental Cell, vol. 14, no. 4, pp. 507-522 . https://doi.org/10.1016/j.devcel.2008.02.001
Summary We have used a human artificial chromosome (HAC) to manipulate the epigenetic state of chromatin within an active kinetochore. The HAC has a dimeric α-satellite repeat containing one natural monomer with a CENP-B binding site, and one comple
Publikováno v:
Cell Reports, Vol 4, Iss 2, Pp 231-237 (2013)
SummaryPredictable operation of engineered biological circuitry requires the knowledge of host factors that compete or interfere with designed function. Here, we perform a detailed analysis of the interaction between constitutive expression from a te
Autor:
Simona Paro, Silvia Vivarelli, Silvia M.L. Barabino, Daniel Schümperli, Stefano Cardinale, Marc-David Ruepp, Chiara Aringhieri
Publikováno v:
MOLECULAR BIOLOGY OF THE CELL
Export of mRNA from the nucleus is linked to proper processing and packaging into ribonucleoprotein complexes. Although several observations indicate a coupling between mRNA 3′ end formation and export, it is not known how these two processes are m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::720ff40c6f21e7e019987cea04afab2a
http://hdl.handle.net/10281/7844
http://hdl.handle.net/10281/7844
Autor:
Sandrine Ruchaud, Susana A. Ribeiro, Xuemei Yuan, Zuojun Yue, William C. Earnshaw, Ciaran G. Morrison, Fan Lai, Reto Gassmann, Hiromi Ogawa, Ana Carvalho, Stefano Cardinale, Elisabet Gudmundsdottir, Zhenjie Xu
Publikováno v:
The Journal of Cell Biology
Yue, Z, Carvalho, A, Xu, Z, Yuan, X, Cardinale, S, Ribeiro, S, Lai, F, Ogawa, H, Gudmundsdottir, E, Gassmann, R, Morrison, C G, Ruchaud, S & Earnshaw, W C 2008, ' Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line ', Journal of Cell Biology, vol. 183, no. 2, pp. 279-296 . https://doi.org/10.1083/jcb.200806118
Yue, Z, Carvalho, A, Xu, Z, Yuan, X, Cardinale, S, Ribeiro, S, Lai, F, Ogawa, H, Gudmundsdottir, E, Gassmann, R, Morrison, C G, Ruchaud, S & Earnshaw, W C 2008, ' Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line ', Journal of Cell Biology, vol. 183, no. 2, pp. 279-296 . https://doi.org/10.1083/jcb.200806118
Survivin is a key cellular protein thought to function in apoptotic regulation, mitotic progression, or possibly both. In this study, we describe the isolation of two conditional knockouts of the survivin gene in chicken DT40 cells. DT40 cells lackin