Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefano Antonucci"'
Autor:
Oumayma Aousji, Simone Feldengut, Stefano Antonucci, Michael Schön, Tobias M. Boeckers, Jakob Matschke, Christian Mawrin, Albert C. Ludolph, Kelly Del Tredici, Francesco Roselli, Heiko Braak
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Amyotrophic Lateral Sclerosis (ALS) is mainly characterized by the degeneration of corticospinal neurons and spinal α-motoneurons; vulnerable cells display prominent pTDP-43 inclusions. Evidence gathered from genetics, murine models, and iP
Externí odkaz:
https://doaj.org/article/4664094b4ba54e45911f4a144f8e5258
Autor:
David Bayer, Stefano Antonucci, Hans-Peter Müller, Rami Saad, Luc Dupuis, Volker Rasche, Tobias M. Böckers, Albert C. Ludolph, Jan Kassubek, Francesco Roselli
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-17 (2021)
Abstract Background Increased catabolism has recently been recognized as a clinical manifestation of amyotrophic lateral sclerosis (ALS). The hypothalamic systems have been shown to be involved in the metabolic dysfunction in ALS, but the exact exten
Externí odkaz:
https://doaj.org/article/a6593394dc8947b5b66f4a710304a553
Autor:
Jelena Scekic-Zahirovic, Inmaculada Sanjuan-Ruiz, Vanessa Kan, Salim Megat, Pierre De Rossi, Stéphane Dieterlé, Raphaelle Cassel, Marguerite Jamet, Pascal Kessler, Diana Wiesner, Laura Tzeplaeff, Valérie Demais, Sonu Sahadevan, Katharina M. Hembach, Hans-Peter Muller, Gina Picchiarelli, Nibha Mishra, Stefano Antonucci, Sylvie Dirrig-Grosch, Jan Kassubek, Volker Rasche, Albert Ludolph, Anne-Laurence Boutillier, Francesco Roselli, Magdalini Polymenidou, Clotilde Lagier-Tourenne, Sabine Liebscher, Luc Dupuis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mutations in the RNA binding protein FUS are associated with ALS. Here the authors show that in FUS knock-in mice there is a progressive increase in neuronal activity in the frontal cortex which is associated with altered synaptic gene expression.
Externí odkaz:
https://doaj.org/article/81d53965ba1c4f5cbe4fa11bc13113fd
Autor:
Tobias M. Böckers, Albert C. Ludolph, Jan Kassubek, David Bayer, Luc Dupuis, Hans-Peter Müller, Stefano Antonucci, Volker Rasche, Rami Saad, Francesco Roselli
Publikováno v:
Translational Neurodegeneration, Vol 10, Iss 1, Pp 1-17 (2021)
Translational Neurodegeneration
Translational Neurodegeneration, [London] : BioMed Central, 2012-, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational Neurodegeneration, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational neurodegeneration 10(1), 17 (2021). doi:10.1186/s40035-021-00241-6
Translational Neurodegeneration
Translational Neurodegeneration, [London] : BioMed Central, 2012-, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational Neurodegeneration, 2021, 10 (1), pp.17. ⟨10.1186/s40035-021-00241-6⟩
Translational neurodegeneration 10(1), 17 (2021). doi:10.1186/s40035-021-00241-6
Background Increased catabolism has recently been recognized as a clinical manifestation of amyotrophic lateral sclerosis (ALS). The hypothalamic systems have been shown to be involved in the metabolic dysfunction in ALS, but the exact extent of hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975db4967a8ff48ee26982bd77308f6e
https://doaj.org/article/a6593394dc8947b5b66f4a710304a553
https://doaj.org/article/a6593394dc8947b5b66f4a710304a553
Autor:
Francesco Roselli, Tobias M. Boeckers, Albert C. Ludolph, Luc Dupuis, Hans-Peter Müller, Jan Kassubek, Stefano Antonucci, David Bayer
Increased catabolism is a new clinical manifestation of Amyotrophic Lateral Sclerosis. A dysfunction of lateral hypothalamus may drive hypermetabolism in ALS; however, Its causes and anatomical substrates are unknown. We hypothesize that disruption c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::290fdba8e7299f3a171a2725c3812819
https://doi.org/10.1101/2020.11.28.402065
https://doi.org/10.1101/2020.11.28.402065
