Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Stefano Angiari"'
Autor:
Stefano Angiari, Giuseppina D'Alessandro, Rosa Chiara Paolicelli, Ilaria Prada, Eleonora Vannini
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/5fd5932502be4c4cab38af1fcd408e97
Autor:
Johannes Fessler, Stefano Angiari
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Immunosenescence is a state of dysregulated leukocyte function characterised by arrested cell cycle, telomere shortening, expression of markers of cellular stress, and secretion of pro-inflammatory mediators. Immunosenescence principally develops dur
Externí odkaz:
https://doaj.org/article/a4b09036885f46fe903c6e888b839bc0
Autor:
Silvia Dusi, Stefano Angiari, Enrica Caterina Pietronigro, Nicola Lopez, Gabriele Angelini, Elena Zenaro, Vittorina Della Bianca, Gabriele Tosadori, Francesca Paris, Antonella Amoruso, Tommaso Carlucci, Gabriela Constantin, Barbara Rossi
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Leukocyte trafficking is a key event during autoimmune and inflammatory responses. The subarachnoid space (SAS) and cerebrospinal fluid are major routes for the migration of encephalitogenic T cells into the central nervous system (CNS) during experi
Externí odkaz:
https://doaj.org/article/d6041f84d3dd452e908356947098d14f
Autor:
Mark M. Hughes, Alexander Hooftman, Stefano Angiari, Padmaja Tummala, Zbigniew Zaslona, Marah C. Runtsch, Anne F. McGettrick, Caroline E. Sutton, Ciana Diskin, Melissa Rooke, Shuhei Takahashi, Srinivasan Sundararaj, Marco G. Casarotto, Jane E. Dahlstrom, Eva M. Palsson-McDermott, Sinead C. Corr, Kingston H.G. Mills, Roger J.S. Preston, Nouri Neamati, Yiyue Xie, Jonathan B. Baell, Philip G. Board, Luke A.J. O’Neill
Publikováno v:
Cell Reports, Vol 29, Iss 1, Pp 151-161.e5 (2019)
Summary: The NLRP3 inflammasome is a cytosolic complex sensing phagocytosed material and various damage-associated molecular patterns, triggering production of the pro-inflammatory cytokines interleukin-1 beta (IL)-1β and IL-18 and promoting pyropto
Externí odkaz:
https://doaj.org/article/655fe3fa8e5148bd966bc89b672d9785
Autor:
Alessia Farinazzo, Stefano Angiari, Ermanna Turano, Edoardo Bistaffa, Silvia Dusi, Serena Ruggieri, Roberta Bonafede, Raffaella Mariotti, Gabriela Constantin, Bruno Bonetti
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Cell based-therapies represent promising strategies for the treatment of neurological diseases. We have previously shown that adipose stem cells (ASC) ameliorate chronic experimental autoimmune encephalomyelitis (EAE). Recent evidence indica
Externí odkaz:
https://doaj.org/article/60be3a2ae4e447ec87734d6e61987829
Autor:
Hauke J. Weiss, Stefano Angiari
Publikováno v:
Metabolites, Vol 10, Iss 10, p 418 (2020)
In the past decade, the rise of immunometabolism has fundamentally reshaped the face of immunology. As the functions and properties of many (immuno)metabolites have now been well described, their exchange among cells and their environment have only r
Externí odkaz:
https://doaj.org/article/52ed439d15024bc8afbf4ddbb4ae1d8e
Autor:
Marita Bosticardo, Silvia Musio, Elena Fontana, Stefano Angiari, Elena Draghici, Gabriela Constantin, Pietro L Poliani, Rosetta Pedotti, Anna Villa
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86942 (2014)
Wiskott-Aldrich Syndrome protein (WASP) is a key regulator of the actin cytoskeleton in hematopoietic cells. Defective expression of WASP leads to multiple abnormalities in different hematopoietic cells. Despite severe impairment of T cell function,
Externí odkaz:
https://doaj.org/article/0258c4233d0d43f88b93b3773fcfbedb
Autor:
Rosa C. Paolicelli, Stefano Angiari
Publikováno v:
Seminars in Cell & Developmental Biology. 94:129-137
Since the observation that obesity-associated low-grade chronic inflammation is a crucial driver for the onset of systemic metabolic disorders such as type 2 diabetes, a number of studies have highlighted the role of both the innate and the adaptive
Autor:
Marah C. Runtsch, Stefano Angiari, Alexander Hooftman, Ridhima Wadhwa, Yanling Zhang, Yunan Zheng, Joseph S. Spina, Melanie C. Ruzek, Maria A. Argiriadi, Anne F. McGettrick, Rui Santalla Mendez, Alessia Zotta, Christian G. Peace, Aoife Walsh, Roberta Chirillo, Emily Hams, Padraic G. Fallon, Ranjith Jayaraman, Kamal Dua, Alexandra C. Brown, Richard Y. Kim, Jay C. Horvat, Philip M. Hansbro, Chu Wang, Luke A.J. O’Neill
Publikováno v:
Cell Metabolism
The Krebs cycle-derived metabolite itaconate and its derivatives suppress the inflammatory response in pro-inflammatory "M1" macrophages. However, alternatively activated "M2" macrophages can take up itaconate. We therefore examined the effect of ita
Autor:
Stefano Angiari, Hauke J Weiss
Publikováno v:
Metabolites
Metabolites, Vol 10, Iss 418, p 418 (2020)
Metabolites, Vol 10, Iss 418, p 418 (2020)
In the past decade, the rise of immunometabolism has fundamentally reshaped the face of immunology. As the functions and properties of many (immuno)metabolites have now been well described, their exchange among cells and their environment have only r