Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stefano Acali"'
Autor:
Diego Marescotti, Carole Mathis, Vincenzo Belcastro, Patrice Leroy, Stefano Acali, Florian Martin, Rémi Dulize, David Bornand, Dariusz Peric, Emmanuel Guedj, Laura Ortega Torres, Matteo Biasioli, Matthieu Fuhrimann, Estela Fernandes, Felix Frauendorfer, Ignacio Gonzalez Suarez, Davide Sciuscio, Nikolai V. Ivanov, Manuel C. Peitsch, Julia Hoeng
Publikováno v:
Toxicology Reports, Vol 7, Iss , Pp 67-80 (2020)
The development of reduced-risk products aims to provide alternatives to cigarettes that present less risk of harm for adult smokers. Responsible use of flavoring substances in these products may fulfill an important role in product acceptance. While
Externí odkaz:
https://doaj.org/article/68c51b0570854c5e873f9c4ebe2b2a39
Autor:
Ignacio Gonzalez Suarez, Remi Dulize, Dariusz Peric, Patrice Leroy, Felix Frauendorfer, Matteo Biasioli, Stefano Acali, Manuel C. Peitsch, Julia Hoeng, Diego Marescotti, Emmanuel Guedj, Davide Sciuscio, Nikolai V. Ivanov, Florian Martin, Estela Fernandes, Matthieu Fuhrimann, Vincenzo Belcastro, David Bornand, Carole Mathis, Laura Ortega Torres
Publikováno v:
Toxicology Reports, Vol 7, Iss, Pp 67-80 (2020)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • A 3-step approach combining 1) real-time cytotoxicity, 2) high-content screening and 3) gene expression analysis was developed in NHBE cells. • Different scoring methods were developed enabling a ranking based
Highlights • A 3-step approach combining 1) real-time cytotoxicity, 2) high-content screening and 3) gene expression analysis was developed in NHBE cells. • Different scoring methods were developed enabling a ranking based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7345c2900d7d86b551b3cb2a12506cd8
http://www.sciencedirect.com/science/article/pii/S2214750019304548
http://www.sciencedirect.com/science/article/pii/S2214750019304548
Autor:
Manuel C. Peitsch, Vincenzo Belcastro, Filipe Bonjour, Julia Hoeng, Stephane Cano, Stefano Acali, Nikolai V. Ivanov, Florian Martin, Ignacio Gonzalez-Suarez, Diego Marescotti, Carine Poussin
Publikováno v:
Bioinformatics
Summary GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ed679910a669a0e991e8f002eb6064
http://europepmc.org/articles/PMC6792086
http://europepmc.org/articles/PMC6792086
Autor:
Patrice Leroy, Shoaib Majeed, Alain Sewer, Stefano Acali, Anita R. Iskandar, Diego Marescotti, Emmanuel Guedj, Athanasios Kondylis, Julia Hoeng, Bjorn Titz, Filippo Zanetti, Vincenzo Belcastro, Keyur Trivedi, Manuel C. Peitsch, Stefan Frentzel, Celine Merg, Laura Ortega Torres, Thomas Schneider, Sandro Steiner, Nikolai V. Ivanov, Florian Martin
Publikováno v:
Archives of toxicology. 93(11)
We previously proposed a systems toxicology framework for in vitro assessment of e-liquids. The framework starts with the first layer aimed at screening the potential toxicity of e-liquids, followed by the second layer aimed at investigating the toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7937edcda5694a064307ea532dfd18
https://pubmed.ncbi.nlm.nih.gov/31494692
https://pubmed.ncbi.nlm.nih.gov/31494692
Autor:
Dariusz Peric, Claudius Pak, Stefano Acali, David Bornand, Julia Hoeng, Emmanuel Guedj, Athanasios Kondylis, Nikolai V. Ivanov, Elodie Maluenda, Didier Goedertier, Alexandra Laurent, Ignacio Gonzalez Suarez, Karine Baumer, Remi Dulize, Diego Marescotti, Marco van der Toorn, Manuel C. Peitsch, Carine Poussin, Walter K. Schlage
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 120
Cigarette smoking causes cardiovascular diseases. Heating tobacco instead of burning it reduces the amount of toxic compounds in the aerosol and may exert a reduced impact on health compared with cigarette smoke. Aqueous extract from the aerosol of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e99f1474dd47de099361a9f0e58a7ea
https://pubmed.ncbi.nlm.nih.gov/30026091
https://pubmed.ncbi.nlm.nih.gov/30026091
Autor:
Ignacio Gonzalez Suarez, Stefano Acali, Alexandra Laurent, Diego Marescotti, Julia Hoeng, Stephanie Johne, Stefan Frentzel, Manuel C. Peitsch
Publikováno v:
Journal of Visualized Experiments : JoVE
Cigarette smoke (CS) is a major risk factor for cardiovascular and lung diseases. Because CS is a complex aerosol containing more than 7,000 chemicals1 it is challenging to assess the contributions of individual constituents to its overall toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808217a680d98dff070d6322baa2eab2
https://doi.org/10.3791/53987-v
https://doi.org/10.3791/53987-v
Autor:
Stefano Acali, Didier Goedertier, Stefan Frentzel, Stephanie Johne, Ignacio Gonzalez-Suarez, Nikolai V. Ivanov, Florian Martin, Manuel C. Peitsch, Remi Dulize, Emmanuel Guedj, Julia Hoeng, Karine Baumer, Carole Mathis, Dariusz Peric, Diego Marescotti
Publikováno v:
Chemical research in toxicology. 29(1)
Cigarette smoke increases the risk for respiratory and other diseases. Although smoking prevalence has declined over the years, millions of adults choose to continue to smoke. Modified risk tobacco products (MRTPs) are potentially valuable tools for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb83499263b199e8a75b8d010210ce7
https://pubmed.ncbi.nlm.nih.gov/26651182
https://pubmed.ncbi.nlm.nih.gov/26651182
Autor:
Domenico Lazzaro, Helenia Ansuini, Alfredo Nicosia, Gennaro Ciliberto, Alessandra Vitelli, Valentina Paradisi, Annalisa Meola, Claudia Santini, Nicola La Monica, Alessandra Luzzago, Zeynep Gunes, Stefano Acali, Monica Pezzanera, Federica Mori
Publikováno v:
Journal of Oncology, Vol 2009 (2009)
Journal of Oncology
Journal of Oncology
The EphA2 receptor tyrosine kinase is overexpressed in a variety of human epithelial cancers and is a determinant of malignant cellular behavior in pancreatic adenocarcinoma cells. Moreover, it is expressed in tumor endothelium and its activation pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2251eb073250357d2bb790c68d68c9ec
https://doi.org/10.1155/2009/951917
https://doi.org/10.1155/2009/951917
Autor:
Bruno Bruni Ercole, Riccardo Cortese, Armin Lahm, Anna Tramontano, Rosamaria Roccasecca, Monica Pezzanera, Helenia Ansuini, Alessandra Vitelli, Stefano Acali, Jane A. McKeating, Elisa Scarselli, Asutosh T. Yagnik, Alfredo Nicosia, Annalisa Meola
Publikováno v:
Journal of Virology. 77:1856-1867
The envelope glycoprotein E2 of hepatitis C virus (HCV) is the target of neutralizing antibodies and is presently being evaluated as an HCV vaccine candidate. HCV binds to human cells through the interaction of E2 with the tetraspanin CD81, a putativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5313f426456c1c2707901b2f62cec0
https://doi.org/10.1128/jvi.77.3.1856-1867.2003
https://doi.org/10.1128/jvi.77.3.1856-1867.2003
Autor:
Cinzia Traboni, Alessandra Vitelli, Elisa Scarselli, Alfredo Nicosia, Rosa Maria Roccasecca, Stefano Acali, Gessica Filocamo, Helenia Ansuini, Raffaele Cerino, Riccardo Cortese
Publikováno v:
The EMBO Journal. 21:5017-5025
We discovered that the hepatitis C virus (HCV) envelope glycoprotein E2 binds to human hepatoma cell lines independently of the previously proposed HCV receptor CD81. Comparative binding studies using recombinant E2 from the most prevalent 1a and 1b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90312ff1fb42779c4a5ecaad3e5af0c6
https://doi.org/10.1093/emboj/cdf529
https://doi.org/10.1093/emboj/cdf529