Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Stefano, Loizzo"'
Autor:
Chiara Giuseppina Bonomi, Martina Assogna, Martina Gaia Di Donna, Francesca Bernocchi, Vincenzo De Lucia, Marzia Nuccetelli, Denise Fiorelli, Stefano Loizzo, Nicola Biagio Mercuri, Giacomo Koch, Alessandro Martorana, Caterina Motta
Publikováno v:
Journal of Alzheimer's Disease. 92:1385-1397
Background: Many transversal mechanisms act synergistically at different time-points in the cascade of Alzheimer’s disease (AD), since amyloid-β (Aβ) deposition, tau pathology, and neuroinflammation influence each other. Objective: We explored th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb3da5d0af7ef517903502419f01e0cb
https://doi.org/10.3233/jad-221010
https://doi.org/10.3233/jad-221010
Autor:
Valeria Messina, Stefano Loizzo, Sara Travaglione, Lucia Bertuccini, Maria Condello, Fabiana Superti, Marco Guidotti, Pietro Alano, Francesco Silvestrini, Carla Fiorentini
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213529 (2019)
Plasmodium falciparum severe malaria causes more than 400,000 deaths every year. One feature of P. falciparum-parasitized erythrocytes (pRBC) leading to cerebral malaria (CM), the most dangerous form of severe malaria, is cytoadherence to endothelium
Externí odkaz:
https://doaj.org/article/11ed5ba5fe8847f4b86cb48efd07962d
Autor:
Sara Travaglione, Stefano Loizzo, Rosa Vona, Giulia Ballan, Roberto Rivabene, Danila Giordani, Marco Guidotti, Maria Luisa Dupuis, Zaira Maroccia, Monica Baiula, Roberto Rimondini, Gabriele Campana, Carla Fiorentini
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3390 (2020)
Several chronic neuroinflammatory diseases, including Parkinson’s disease (PD), have the so-called ‘redox imbalance’ in common, a dynamic system modulated by various factors. Among them, alteration of the mitochondrial functionality can cause o
Externí odkaz:
https://doaj.org/article/5e3b80b26ad544258fe7b940465351a4
Autor:
Andrea Colarusso, Zaira Maroccia, Ermenegilda Parrilli, Elena Angela Pia Germinario, Andrea Fortuna, Stefano Loizzo, Laura Ricceri, Maria Luisa Tutino, Carla Fiorentini, Alessia Fabbri
Publikováno v:
Toxins, Vol 12, Iss 5, p 291 (2020)
Among gliomas, primary tumors originating from glial cells, glioblastoma (GBM) identified as WHO grade IV glioma, is the most common and aggressive malignant brain tumor. We have previously shown that the Escherichia coli protein toxin cytotoxic necr
Externí odkaz:
https://doaj.org/article/9d1b37275d5b425d85e0c78158ae8fb1
Autor:
Alessandro Martorana, Gabriele Campana, Andrea Fortuna, Stefano Loizzo, Zaira Maroccia, Roberto Rimondini, Giacomo Koch
Publikováno v:
Brain Research Bulletin. 176:18-24
The cholinergic neurotransmitter system in the brain is crucial in processing information related to cognitive, behavioral, and motor functions. A cholinergic dysfunction has been correctly described as one of the primary causes of neurodegenerative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef610df4343e2ed262c09c6ef501463d
https://doi.org/10.1016/j.brainresbull.2021.08.005
https://doi.org/10.1016/j.brainresbull.2021.08.005
Autor:
Alessia Fabbri, Sara Cori, Cristiana Zanetti, Marco Guidotti, Massimo Sargiacomo, Stefano Loizzo, Carla Fiorentini
Publikováno v:
Toxins, Vol 7, Iss 11, Pp 4610-4621 (2015)
Eukaryotic cells secrete extracellular vesicles (EVs), either constitutively or in a regulated manner, which represent an important mode of intercellular communication. EVs serve as vehicles for transfer between cells of membrane and cytosolic protei
Externí odkaz:
https://doaj.org/article/98a76407a0534d56afe0f3ab2ae32a04
Publikováno v:
Toxins, Vol 6, Iss 1, Pp 270-282 (2014)
The Cytotoxic Necrotizing Factor 1 (CNF1), a protein toxin from pathogenic E. coli, modulates the Rho GTPases, thus, directing the organization of the actin cytoskeleton. In the nervous system, the Rho GTPases play a key role in several processes, co
Externí odkaz:
https://doaj.org/article/2e9b3b534b0f4ac499643495829296a6
Publikováno v:
Toxins, Vol 5, Iss 8, Pp 1462-1474 (2013)
Certain strains of Escherichia coli have been indicated as a risk factor for colon cancer. E. coli is a normal inhabitant of the human intestine that becomes pathogenic, especially in extraintestinal sites, following the acquisition of virulence fact
Externí odkaz:
https://doaj.org/article/66790b14e60840f184f5aa69ff06e393
Autor:
Alessia Fabbri, Sara Travaglione, Zaira Maroccia, Marco Guidotti, Ciro Leonardo Pierri, Guido Primiano, Serenella Servidei, Stefano Loizzo, Carla Fiorentini
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 7, p 1825 (2018)
The Escherichia coli protein toxin cytotoxic necrotizing factor 1 (CNF1), which acts on the Rho GTPases that are key regulators of the actin cytoskeleton, is emerging as a potential therapeutic tool against certain neurological diseases characterized
Externí odkaz:
https://doaj.org/article/d6de220316f04c448b1e9b71e24330e2
Autor:
Sara Travaglione, Giulia Ballan, Andrea Fortuna, Alberto Ferri, Marco Guidotti, Gabriele Campana, Carla Fiorentini, Stefano Loizzo
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140495 (2015)
Epilepsy, one of the most common conditions affecting the brain, is characterized by neuroplasticity and brain cell energy defects. In this work, we demonstrate the ability of the Escherichia coli protein toxin cytotoxic necrotizing factor 1 (CNF1) t
Externí odkaz:
https://doaj.org/article/dfd0223e3c404b1585c7f84dde4da125