Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Stefanny M. Figueroa"'
Autor:
Stefanny M. Figueroa, Jean-Philippe Bertocchio, Toshifumi Nakamura, Soumaya El-Moghrabi, Frédéric Jaisser, Cristián A. Amador
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1373 (2023)
Tacrolimus (Tac) is a calcineurin inhibitor commonly used as an immunosuppressor after solid organ transplantation. However, Tac may induce hypertension, nephrotoxicity, and an increase in aldosterone levels. The activation of the mineralocorticoid r
Externí odkaz:
https://doaj.org/article/0d9097bf70344c53b4062546d60771f3
Autor:
Aarón Guerrero, Bruna Visniauskas, Pilar Cárdenas, Stefanny M. Figueroa, Jorge Vivanco, Nicolas Salinas-Parra, Patricio Araos, Quynh My Nguyen, Modar Kassan, Cristián A. Amador, Minolfa C. Prieto, Alexis A. Gonzalez
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Externí odkaz:
https://doaj.org/article/8b6d87c9c741445a88e2feac0178c38e
Autor:
Stefanny M. Figueroa, Mauricio Lozano, Carolina Lobos, Matthew T. Hennrikus, Alexis A. Gonzalez, Cristián A. Amador
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Chronic kidney disease (CKD) is characterized by renal dysfunction, which is a common feature of other major diseases, such as hypertension and diabetes. Unilateral ureteral obstruction (UUO) has been used as a model of CKD in experimental animals an
Externí odkaz:
https://doaj.org/article/8a9aed299bc84183ac2f987851132ff5
Autor:
Stefanny M. Figueroa, Patricio Araos, Javier Reyes, Basile Gravez, Jonatan Barrera-Chimal, Cristián A. Amador
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 404 (2021)
Renal diseases are a global health concern, and nearly 24% of kidney disease patients are overweight or obese. Particularly, increased body mass index has been correlated with oxidative stress and urinary albumin excretion in kidney disease patients,
Externí odkaz:
https://doaj.org/article/27c060f0186340929ecd2d2155a797f1
Publikováno v:
Hypertension. 78
Immune cells play a major role in the development and progression of hypertension. Previous studies have shown that antigen presenting cells (APCs), such as macrophages (Mø) and dendritic cells (DCs) are particularly abundant in kidney. However, the
Autor:
Tak W. Mak, Rodrigo Pacheco, Luis Michea, Alexandra Espinoza, Thorsten Berger, Frederic Jaisser, Cristián A. Amador, Carolina Prado, Stefanny M. Figueroa, Mauricio Lozano, Patricio Araos
Publikováno v:
Journal of Hypertension. 37:1482-1492
Background:Adaptive immunity is crucial in cardiovascular and renal inflammation/fibrosis upon hyperactivation of mineralocorticoid receptor. We have previously demonstrated that dendritic cells can respond to mineralocorticoid receptor activation, a
Autor:
Jorge Vivanco, Cristián A. Amador, Alexis A. Gonzalez, Pilar Cárdenas, Quynh My Nguyen, Bruna Visniauskas, Stefanny M. Figueroa, Nicolas Salinas-Parra, Patricio Araos, Minolfa C. Prieto, Modar Kassan, Aaron Guerrero
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Autor:
Aarón, Guerrero, Bruna, Visniauskas, Pilar, Cárdenas, Stefanny M, Figueroa, Jorge, Vivanco, Nicolas, Salinas-Parra, Patricio, Araos, Quynh My, Nguyen, Modar, Kassan, Cristián A, Amador, Minolfa C, Prieto, Alexis A, Gonzalez
Publikováno v:
Frontiers in Cardiovascular Medicine
Diabetes mellitus (DM) causes high glucose (HG) levels in the plasma and urine. The (pro)renin receptor (PRR) is a key regulator of renal Na+ handling. PRR is expressed in intercalated (IC) cells of the collecting duct (CD) and binds renin to promote
Autor:
Alexis A. Gonzalez, Cristian Reyes-Martinez, Minolfa C. Prieto, Alex Gonzalez-Vergara, Leonardo Zamora, Catherina A. Cuevas, Nicolas Salinas-Parra, Stefanny M. Figueroa, Nicole Roldán
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 44:1134-1144
Recent studies suggested that activation of the PRR upregulates profibrotic markers through reactive oxygen species (ROS) formation; however, the exact mechanisms have not been investigated in CD cells. We hypothesized that activation of the PRR incr
Autor:
Jonatan Barrera-Chimal, Javier Reyes, Patricio Araos, Cristián A. Amador, Basile Gravez, Stefanny M. Figueroa
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 404, p 404 (2021)
Antioxidants, Vol 10, Iss 404, p 404 (2021)
Renal diseases are a global health concern, and nearly 24% of kidney disease patients are overweight or obese. Particularly, increased body mass index has been correlated with oxidative stress and urinary albumin excretion in kidney disease patients,