Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Stefanie Y Tan"'
Autor:
J. Perry Hall, Angela Hadjipanayis, Yogeshwar Kelkar, Stefanie Y. Tan, Thomas A. Wynn, Arun Shipstone
Publikováno v:
The Journal of Immunology. 205:957-967
Metabolic reprogramming plays a central role in T cell activation and differentiation, and the inhibition of key metabolic pathways in activated T cells represents a logical approach for the development of new therapeutic agents for treating autoimmu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bb07f537770eb7079b5fcbd3ba190e
https://doi.org/10.4049/jimmunol.2000137
https://doi.org/10.4049/jimmunol.2000137
Publikováno v:
FEBS Lett
C1q/TNF-related protein 12 (CTRP12) is an antidiabetic adipokine whose circulating levels are reduced in obesity and diabetes. Although partial and complete loss-of-function mouse models suggest a role for CTRP12 in modulating lipid metabolism and ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3014052607b9e6eeaba918c998769346
https://doi.org/10.1002/1873-3468.13895
https://doi.org/10.1002/1873-3468.13895
Autor:
Susana Rodriguez, G. William Wong, Ageline Sahagun, Dylan C. Sarver, Hannah C. Little, Xia Lei, Stefanie Y. Tan, Ashley N. Stewart
Publikováno v:
The FASEB Journal. 33:8666-8687
We recently described myonectin (also known as erythroferrone) as a novel skeletal muscle–derived myokine with metabolic functions. Here, we use a genetic mouse model to determine myonectin’s requirement for metabolic homeostasis. Female myonecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6810d1e3e27a9d4c9ad0b1ef7b2d12db
https://doi.org/10.1096/fj.201900520r
https://doi.org/10.1096/fj.201900520r
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88535 (2014)
CTRP2 is a secreted plasma protein of the C1q family that enhances glycogen deposition and fat oxidation in cultured myotubes. Its in vivo metabolic function, however, has not been established. We show here that acute and chronic metabolic perturbati
Externí odkaz:
https://doaj.org/article/9ce47b23216e4e80835f29ce764b70f8
Autor:
Dylan C. Sarver, G. William Wong, Susana Rodriguez, Dan E. Berkowitz, Jennifer L. Pluznick, Hannah C. Little, Paride Fenaroli, Michael Delannoy, C. Conover Talbot, Avi Z. Rosenberg, Stefanie Y. Tan, Parnaz Daneshpajouhnejad, Sandeep Jandu
Publikováno v:
Am J Physiol Regul Integr Comp Physiol
C1q/TNF-related protein 1 (CTRP1) is an endocrine factor with metabolic, cardiovascular, and renal functions. We previously showed that aged Ctrp1-knockout (KO) mice fed a control low-fat diet develop renal hypertrophy and dysfunction. Since aging an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4c62b026925cd41e5d446679a072d5
https://pubmed.ncbi.nlm.nih.gov/33085906
https://pubmed.ncbi.nlm.nih.gov/33085906
Autor:
Susana Rodriguez, Stefanie Y. Tan, Hannah C. Little, G. William Wong, Xia Lei, Dylan C. Sarver, Xi Cao
Publikováno v:
Am J Physiol Endocrinol Metab
Secreted hormones facilitate tissue cross talk to maintain energy balance. We previously described C1q/TNF-related protein 12 (CTRP12) as a novel metabolic hormone. Gain-of-function and partial-deficiency mouse models have highlighted important roles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c41504a8cf949dbd1bba350d8e3de15
https://europepmc.org/articles/PMC7468785/
https://europepmc.org/articles/PMC7468785/
Autor:
Stefanie Y, Tan, Yogeshwar, Kelkar, Angela, Hadjipanayis, Arun, Shipstone, Thomas A, Wynn, J Perry, Hall
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 205(4)
Metabolic reprogramming plays a central role in T cell activation and differentiation, and the inhibition of key metabolic pathways in activated T cells represents a logical approach for the development of new therapeutic agents for treating autoimmu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89e5d6b2b1823efe2567cae670261ce4
https://pubmed.ncbi.nlm.nih.gov/32641388
https://pubmed.ncbi.nlm.nih.gov/32641388
Publikováno v:
Biochemistry
C1q/TNF-related protein 12 (CTRP12) is a secreted regulator of glucose and lipid metabolism. It circulates in plasma as a full-length protein or as a cleaved isoform generated by furin/PCSK3 cleavage. These isoforms preferentially activate different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fa239e3966172f294ff498fb67cf030
https://doi.org/10.1021/acs.biochem.8b00528
https://doi.org/10.1021/acs.biochem.8b00528
Autor:
G. William Wong, Stefanie Y. Tan, Francesca M. Cali, Christopher Hug, Andrew Wolfe, Xia Lei, Susana Rodriguez, Hannah C. Little
Publikováno v:
Molecular & Cellular Proteomics. 17:1546-1563
Exercise is known to confer major health benefits, but the underlying mechanisms are not well understood. The systemic effects of exercise on multi-organ systems are thought to be partly because of myokines/cytokines secreted by skeletal muscle. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686fc6c9b6121862dcac6bf06456ec16
https://doi.org/10.1074/mcp.ra118.000794
https://doi.org/10.1074/mcp.ra118.000794
Publikováno v:
Physiological Genomics. 48:936-949
Secreted hormones play pivotal roles in tissue cross talk to maintain physiologic blood glucose and lipid levels. We previously showed that C1q/TNF-related protein 12 (CTRP12) is a novel secreted protein involved in regulating glucose metabolism whos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd1727edfa0e24614d3687700a18467
https://doi.org/10.1152/physiolgenomics.00111.2016
https://doi.org/10.1152/physiolgenomics.00111.2016