Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Stefanie Traub"'
Autor:
Teresa Bluhmki, Stefanie Traub, Ann-Kathrin Müller, Sarah Bitzer, Eva Schruf, Marie-Therese Bammert, Marcel Leist, Florian Gantner, James P Garnett, Ralf Heilker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Abstract In order to circumvent the limited access and donor variability of human primary alveolar cells, directed differentiation of human pluripotent stem cells (hiPSCs) into alveolar-like cells, provides a promising tool for respiratory disease mo
Externí odkaz:
https://doaj.org/article/09338b009eba44b382db553973d27bc2
Autor:
Ralf Heilker, Eva Schruf, Teresa Bluhmki, Ann-Kathrin Müller, Marie-Therese Bammert, Stefanie Traub, Florian Gantner, James P. Garnett, Sarah Bitzer, Marcel Leist
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-19 (2021)
In order to circumvent the limited access and donor variability of human primary alveolar cells, directed differentiation of human pluripotent stem cells (hiPSCs) into alveolar-like cells, provides a promising tool for respiratory disease modeling an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664fa45854319e069f475a278158c498
Autor:
Eric Simon, Stefanie Traub, Ralf Heilker, Holger Rosenbrock, Lore Florin, Heiko Stahl, Stefan Hörer, Lisa Hospach
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 361:355-365
Brain-derived neurotrophic factor (BDNF) is a central modulator of neuronal development and synaptic plasticity in the central nervous system. This renders the BDNF-modulated tropomyosin receptor kinase B (TrkB) a promising drug target to treat synap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d688193c030888539a5051b66e6a9ad
https://doi.org/10.1124/jpet.117.240184
https://doi.org/10.1124/jpet.117.240184
Publikováno v:
SLAS Discovery. 22:274-286
The advent of human-induced pluripotent stem (hiPS) cell-derived neurons promised to provide better model cells for drug discovery in the context of the central nervous system. This work demonstrates both the upscaling of cellular expansion and the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f68bf4e16d0ce8e6cc1a44bc275e8f0
https://doi.org/10.1177/1087057116678161
https://doi.org/10.1177/1087057116678161
Autor:
Teresa, Bluhmki, Stefanie, Traub, Eva, Schruf, James, Garnett, Florian, Gantner, Daniel, Bischoff, Ralf, Heilker
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1994
In drug discovery, there is an increasing demand for more physiological in vitro models that recapitulate the disease situation in patients. Human induced pluripotent stem (hiPS) cell-derived model cells could serve this purpose. To date, several dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f06a331caf44584a547f303945e0e18
https://pubmed.ncbi.nlm.nih.gov/31124108
https://pubmed.ncbi.nlm.nih.gov/31124108
Autor:
Stefanie, Traub, Ralf, Heilker
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1994
Human induced pluripotent stem (hiPS) cell-derived neurons promise to provide better model cells for drug discovery in the context of neurodegenerative and neuropsychiatric diseases. The neuronal differentiation protocol described encompasses a cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4ac0f72c8911123dc9a323bb3486a35
https://pubmed.ncbi.nlm.nih.gov/31124122
https://pubmed.ncbi.nlm.nih.gov/31124122
Autor:
Ralf Heilker, Stefanie Traub
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994762
Human induced pluripotent stem (hiPS) cell-derived neurons promise to provide better model cells for drug discovery in the context of neurodegenerative and neuropsychiatric diseases. The neuronal differentiation protocol described encompasses a cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec65f88a3a428cee22e3edc7bbb65ad
https://doi.org/10.1007/978-1-4939-9477-9_23
https://doi.org/10.1007/978-1-4939-9477-9_23
Autor:
Daniel Bischoff, Florian Gantner, James P. Garnett, Eva Schruf, Stefanie Traub, Ralf Heilker, Teresa Bluhmki
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994762
In drug discovery, there is an increasing demand for more physiological in vitro models that recapitulate the disease situation in patients. Human induced pluripotent stem (hiPS) cell-derived model cells could serve this purpose. To date, several dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31a8bb8d1f06351d2a890d6dfcacc2fb
https://doi.org/10.1007/978-1-4939-9477-9_9
https://doi.org/10.1007/978-1-4939-9477-9_9
Autor:
José Pedro Gil, Matthias Schwab, Andreas Bitter, Andreas K. Nussler, Rita Piedade, Oliver Burk, Stefanie Traub
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:96-104
Malaria patients are frequently coinfected with HIV and mycobacteria causing tuberculosis, which increases the use of coadministered drugs and thereby enhances the risk of pharmacokinetic drug-drug interactions. Activation of the pregnane X receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab67fc9677328499c94aa39608f0bff2
https://doi.org/10.1128/aac.04140-14
https://doi.org/10.1128/aac.04140-14