Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stefanie Schanz"'
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 4 (2024)
ABSTRACTThe gram-positive bacterium Staphylococcus aureus can invade non-professional phagocytic cells by associating with the plasma protein fibronectin to exploit host cell integrins. Integrin-mediated internalization of these pathogens is facilita
Externí odkaz:
https://doaj.org/article/a6af5c51003e4bf8bc7381b0af39308f
Autor:
Yvonne Lorat, Stefanie Schanz, Nadine Schuler, Gunther Wennemuth, Christian Rübe, Claudia E Rübe
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38165 (2012)
DNA double-strand breaks (DSBs) generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whether breaks
Externí odkaz:
https://doaj.org/article/1649b5834144406096fd3359c4cd602a
Publikováno v:
Clinical Cancer Research. 22:5300-5311
Purpose: Intensity-modulated radiotherapy (IMRT) enables the delivery of high doses to target volume while sparing surrounding nontargeted tissues. IMRT treatment, however, substantially increases the normal tissue volume receiving low-dose irradiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc192209466c5a6c800d12bc348ee22
https://doi.org/10.1158/1078-0432.ccr-15-3081
https://doi.org/10.1158/1078-0432.ccr-15-3081
Autor:
Gisela Taucher-Scholz, Christina U. Brunner, Yvonne Lorat, Burkhard Jakob, Stefanie Schanz, Claudia E. Rübe
Publikováno v:
DNA Repair. 28:93-106
Low- and high-linear energy transfer (LET) ionising radiation are effective cancer therapies, but produce structurally different forms of DNA damage. Isolated DNA damage is repaired efficiently; however, clustered lesions may be more difficult to rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0668551e74391f476c3aee8ab102b7cb
https://doi.org/10.1016/j.dnarep.2015.01.007
https://doi.org/10.1016/j.dnarep.2015.01.007
Publikováno v:
Radiotherapy and Oncology
Background and purpose Intensity-modulated radiation therapy for thoracic malignancies increases the exposure of healthy lung tissue to low-dose radiation. The biological impact of repetitive low-dose radiation on the radiosensitive lung is unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ad64d86f445e98da62fa1ef05de789
Autor:
Ajay K. Malik, Stefanie Schanz, Farbod Shojaei, Hans-Peter Gerber, Napoleone Ferrara, Germaine Fuh, Megan Baldwin, Cuiling Zhong, Xiumin Wu
Publikováno v:
Nature Biotechnology. 25:911-920
Vascular endothelial growth factor (VEGF) is an essential regulator of normal and abnormal blood vessel growth. A monoclonal antibody (mAb) that targets VEGF suppresses tumor growth in murine cancer models and human patients. We investigated cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d75508214ed0ca0c8801e848887edc2
https://doi.org/10.1038/nbt1323
https://doi.org/10.1038/nbt1323
Publikováno v:
Journal of Carcinogenesis & Mutagenesis.
The biological impact of low doses of ionizing radiation on human health and the genetic factors influencing whole organism radio-sensitivity at low doses are unclear. Using mouse strains that varied in genetic DNA repair capacity (C57BL/6, ATM +/+,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe9f3b4d7d8b9e9717704091b19b666
https://doi.org/10.4172/2157-2518.1000196
https://doi.org/10.4172/2157-2518.1000196
Autor:
Lars Kaestner, Stefanie Schanz, Yvonne Lorat, Christian Rübe, Claudia E. Rübe, Nadine Schuler, Li Fan, Gunther Wennemuth
Publikováno v:
DNA repair. 11(10)
The biological consequences of low levels of radiation exposure and their effects on human health are unclear. Ionizing radiation induces a variety of lesions of which DNA double-strand breaks (DSBs) are the most biologically significant, because unr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4230f3a88c5f89e73595827c0fe6dcba
https://pubmed.ncbi.nlm.nih.gov/22947398
https://pubmed.ncbi.nlm.nih.gov/22947398
Autor:
Nadine Schuler, Stefanie Schanz, Claudia E. Rübe, Gunther Wennemuth, Christian Rübe, Yvonne Lorat
Publikováno v:
DNA repair. 10(4)
The recognition and repair of DNA double-strand breaks (DSBs) occurs in the context of highly structured chromatin. Here, we established a transmission electron microscopy (TEM) approach to localize gold-labeled DSB repair components in different chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a06ad018caee61ec023dfefedc918
https://pubmed.ncbi.nlm.nih.gov/21342792
https://pubmed.ncbi.nlm.nih.gov/21342792
Autor:
Nadine Schuler, Yvonne Lorat, Gunther Wennemuth, Christian Rübe, Stefanie Schanz, Claudia E. Rübe
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38165 (2012)
PLoS ONE
PLoS ONE
Purpose DNA double-strand breaks (DSBs) generated by ionizing radiation pose a serious threat to the preservation of genetic and epigenetic information. The known importance of local chromatin configuration in DSB repair raises the question of whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb9ee39b1548a618cc069d65e826d73
https://doi.org/10.1371/journal.pone.0038165
https://doi.org/10.1371/journal.pone.0038165