Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stefanie R Mullins"'
Autor:
Damien J Zanker, Alex J Spurling, Natasha K Brockwell, Katie L Owen, Jasmine M Zakhour, Tina Robinson, Hendrika M Duivenvoorden, Paul J Hertzog, Stefanie R Mullins, Robert W Wilkinson, Belinda S Parker
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 9, Pp n/a-n/a (2020)
Abstract Objectives Loss of tumor‐inherent type I interferon (IFN) signalling has been closely linked to accelerated metastatic progression via decreased immunogenicity and antitumor immunity. Previous studies in murine models of triple‐negative
Externí odkaz:
https://doaj.org/article/61578605bee846698ae1d74398aee779
Autor:
Stefanie R. Mullins, John P. Vasilakos, Katharina Deschler, Iwen Grigsby, Pete Gillis, Julius John, Matthew J. Elder, John Swales, Elina Timosenko, Zachary Cooper, Simon J. Dovedi, Andrew J. Leishman, Nadia Luheshi, James Elvecrog, Ashenafi Tilahun, Richard Goodwin, Ronald Herbst, Mark A. Tomai, Robert W. Wilkinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background Immune checkpoint blockade (ICB) promotes adaptive immunity and tumor regression in some cancer patients. However, in patients with immunologically “cold” tumors, tumor-resident innate immune cell activation may be required to
Externí odkaz:
https://doaj.org/article/664a845e229648008b22d687ebf6b261
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary videos. Representative reconstructed 3D rendering of a Colo205 tumor 3 h after injection of 0.2 µmole/kg of C2Am-750. Signals from C2Am-750, oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (Hb) are shown in green, red and blue re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b293660af54350dae220ee09a01c2b
https://doi.org/10.1158/1078-0432.22463276.v1
https://doi.org/10.1158/1078-0432.22463276.v1
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary figures 1 - 4. Caption for video file.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8b461b7c2a039461eaf997b9ce45034
https://doi.org/10.1158/1078-0432.22463279.v1
https://doi.org/10.1158/1078-0432.22463279.v1
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Purpose: The development of new treatments and their deployment in the clinic may be assisted by imaging methods that allow an early assessment of treatment response in individual patients. The C2A domain of Synaptotagmin-I (C2Am), which binds to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03869d7447f0a5db80e579a7bc991957
https://doi.org/10.1158/1078-0432.c.6525359.v1
https://doi.org/10.1158/1078-0432.c.6525359.v1
Autor:
Kevin M. Brindle, Robert W. Wilkinson, Sarah E. Bohndiek, Richard C.A. Sainson, David Tice, Stefanie R. Mullins, Sarah McGuire, De-En Hu, Susana Ros, André A. Neves, Michal R. Tomaszewski, Bangwen Xie
Supplementary video. Representative reconstructed 3D rendering of a Colo205 tumor before injection of 0.2 µmole/kg of C2Am-750. Signals from C2Am-750, oxygenated hemoglobin (HbO2), deoxygenated hemoglobin (Hb) are shown in green, red and blue respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348c7b3540acce126976d53eaa9de2bd
https://doi.org/10.1158/1078-0432.22463282
https://doi.org/10.1158/1078-0432.22463282
Autor:
Robert W. Wilkinson, Hendrika M. Duivenvoorden, Damien Zanker, Alex J. Spurling, Stefanie R. Mullins, Belinda S. Parker, Tina Robinson, Natasha K Brockwell, Katie L. Owen, Paul J. Hertzog, Jasmine M. Zakhour
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 9, Pp n/a-n/a (2020)
Clinical & Translational Immunology
Clinical & Translational Immunology
Objectives Loss of tumor‐inherent type I interferon (IFN) signalling has been closely linked to accelerated metastatic progression via decreased immunogenicity and antitumor immunity. Previous studies in murine models of triple‐negative breast ca
Autor:
Ching Ching Leow, Scott A. Hammond, Michael Oberst, Li Yan, Stefanie R. Mullins, Lesley Young, Michelle Morrow, Amanda Watkins, Lisa Bamber, Nicholas Holoweckyj, Jane Coates Ulrichsen, Robert W. Wilkinson, Kathy Mulgrew, Rebecca Leyland, John Andrews, Emily Offer, Ross Stewart, Natalie J. Tigue, Athula Herath, David A Leinster, Philip R. Mallinder, Kelly McGlinchey
Publikováno v:
Clinical Cancer Research. 23:3416-3427
Purpose: To generate and characterize a murine GITR ligand fusion protein (mGITRL-FP) designed to maximize valency and the potential to agonize the GITR receptor for cancer immunotherapy. Experimental Design: The EC50 value of the mGITRL-FP was compa
Autor:
Ashenafi Y. Tilahun, Andrew Leishman, Richard J. A. Goodwin, John P. Vasilakos, Robert W. Wilkinson, John G. Swales, Nadia Luheshi, Elina Timosenko, Ronald Herbst, James Elvecrog, Stefanie R. Mullins, Simon J. Dovedi, Pete Gillis, Zachary A. Cooper, Iwen Grigsby, Katharina Deschler, Julius John, Matthew J. Elder, Mark A. Tomai
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Background Immune checkpoint blockade (ICB) promotes adaptive immunity and tumor regression in some cancer patients. However, in patients with immunologically “cold” tumors, tumor-resident innate immune cell activation may be required to prime an
Autor:
Richard C.A. Sainson, Sarah E. Bohndiek, Susana Ros, Kevin M. Brindle, De-En Hu, Bangwen Xie, Sarah McGuire, Stefanie R. Mullins, David A. Tice, André A. Neves, Michal R. Tomaszewski, Robert W. Wilkinson
Purpose: The development of new treatments and their deployment in the clinic may be assisted by imaging methods that allow an early assessment of treatment response in individual patients. The C2A domain of Synaptotagmin-I (C2Am), which binds to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::912c8fef221e9591aec1ca437be1df7d