Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Stefanie Perez-Feliz"'
Autor:
Paul Kreifels, Ilona Bodi, Tibor Hornyik, Gerlind Franke, Stefanie Perez-Feliz, R. Lewetag, Robin Moss, Alessandro Castiglione, David Ziupa, Manfred Zehender, Michael Brunner, Christoph Bode, Katja E. Odening
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 40, Iss , Pp 101001- (2022)
Background: Oxytocin is used therapeutically in psychiatric patients. Many of these also receive anti-depressant or anti-psychotic drugs causing acquired long-QT-syndrome (LQTS) by blocking HERG/IKr. We previously identified an oxytocin-induced QT-pr
Externí odkaz:
https://doaj.org/article/99c765bb8d1541cea0dea16bce4c491e
Autor:
Robin Moss, Eike M Wülfers, Raphaela Lewetag, Tibor Hornyik, Stefanie Perez-Feliz, Tim Strohbach, Marius Menza, Axel Krafft, Katja E Odening, Gunnar Seemann
Publikováno v:
PLoS ONE, Vol 17, Iss 6, p e0270559 (2022)
Computational modeling of electrophysiological properties of the rabbit heart is a commonly used way to enhance and/or complement findings from classic lab work on single cell or tissue levels. Yet, thus far, there was no possibility to extend the sc
Externí odkaz:
https://doaj.org/article/07502221af654144a1c1795e2e1ac866
Autor:
Jessica J Jowais, Marina Rieder, Lucilla Giammarino, Katja E. Odening, Michael Brunner, Christoph Bode, Sara I. Liin, Alessandro Castiglione, Manfred Zehender, Stefanie Perez-Feliz, Eike M. Wülfers, Gideon Koren, Hans Peter Larsson, Tibor Hornyik, István Baczkó, Iask Edler, András Varró, Zsuzsanna Bősze
Publikováno v:
Europace
Aim Long QT syndrome (LQTS) is a cardiac channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Since current therapies often fail to prevent arrhythmic events in certain LQTS subtypes, new therapeutic strategies are needed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b92da804f6ca974a127a57006611b2f
https://doi.org/10.1093/europace/euab228
https://doi.org/10.1093/europace/euab228
Autor:
Sahej Bains, Lucilla Giammarino, Saranda Nimani, Nicolo Alerni, David Tester, Nicolas Christoforou, Julien Louradour, Thomas S. Hof, Olgica Beslac, Miriam Barbieri, Lluis Matas, Andras Horvath, Ruben Lopez, Stefanie Perez-Feliz, Changsung J. Kim, Wei Zhou, Dan Ye, Jacqulyn Jurgensen, Michael A. Barry, Mariana Bego, Lisa Keyes, Jane Owens, Jason Pinkstaff, Gideon Koren, Manfred Zehender, Michael Brunner, Daniela Casoni, Fabien Praz, Andreas Haeberlin, Gabriel Brooks, Katja E. Odening, Michael J. Ackerman
Publikováno v:
Heart Rhythm. 20:S278
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6767b3b1edf598f281d07541cd15161
https://doi.org/10.1016/j.hrthm.2023.03.744
https://doi.org/10.1016/j.hrthm.2023.03.744
Autor:
T Hornyik, K R Moss, Manfred Zehender, Katja E. Odening, N Alerni, Stefanie Perez-Feliz, Michael Brunner, S Nimani, Lucilla Giammarino, R Lewetag, L Matas, Gunnar Seemann
Publikováno v:
European Heart Journal. 42
Background Electro-mechanical (EMC) and mechano-electrical coupling (MEC) are essential for normal cardiac function. Alterations in these can result in increased arrhythmia formation. In “electrical” cardiac diseases, long-QT and short-QT syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3764a0b5bb2ac19ede9b6269b12a6953
https://doi.org/10.1093/eurheartj/ehab724.3213
https://doi.org/10.1093/eurheartj/ehab724.3213
Autor:
David Ziupa, Julia Beck, Gerlind Franke, Stefanie Perez Feliz, Maximilian Hartmann, Gideon Koren, Manfred Zehender, Christoph Bode, Michael Brunner, Katja E Odening
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107210 (2014)
Prolongation of action potential duration (APD), increased spatial APD dispersion, and triangulation are major factors promoting drug-induced ventricular arrhythmia. Preclinical identification of HERG/IKr-blocking drugs and their pro-arrhythmic poten
Externí odkaz:
https://doaj.org/article/bf76935afb7d4de981eb4b6523b6ca7b
Autor:
Katja E. Odening, N Pilia, Marius Menza, Robin Moss, Stefanie Perez-Feliz, R Lewetag, S Jacobi, Christoph Bode, T Hornyik, Gunnar Seemann
Publikováno v:
EP Europace. 23
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): German Research Foundation Background Electrical and mechanical heterogeneities and their interactions (electro-mechanical and mechano-electrical coupling; EMC / ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::561aa45a87b25cbc23657b9033f70ac4
https://doi.org/10.1093/europace/euab116.578
https://doi.org/10.1093/europace/euab116.578
Autor:
Gideon Koren, László Hiripi, P. Major, Michael Brunner, Christoph Bode, Zsuzsanna Bősze, Gerlind Franke, Stefanie Perez-Feliz, Tibor Hornyik, Katja E. Odening, István Baczkó, András Varró, Alessandro Castiglione, Manfred Zehender
Publikováno v:
Hornyik, Tibor; Castiglione, Alessandro; Franke, Gerlind; Perez-Feliz, Stefanie; Major, Péter; Hiripi, László; Koren, Gideon; Bősze, Zsuzsanna; Varró, András; Zehender, Manfred; Brunner, Michael; Bode, Christoph; Baczkó, István; Odening, Katja E. (2020). Transgenic LQT2, LQT5, and LQT2-5 rabbit models with decreased repolarisation reserve for prediction of drug-induced ventricular arrhythmias. British journal of pharmacology, 177(16), pp. 3744-3759. Wiley-Blackwell 10.1111/bph.15098
British Journal of Pharmacology
British Journal of Pharmacology
BACKGROUND AND PURPOSE Reliable prediction of pro-arrhythmic side effects of novel drug candidates is still a major challenge. Although drug-induced pro-arrhythmia occurs primarily in patients with pre-existing repolarisation disturbances, healthy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::110c6ce9bd9a9acff489274e90e1c7a5
Autor:
David Ziupa, Heiko Bugger, Anna Ryan de Medeiros, Marius Menza, Corinna N. Lang, Stefanie Perez-Feliz, Jan C. Behrends, Michael Brunner, Naga Deepa Pantulu, Lea Mettke, Konstantin Michaelides, Zoltán Doleschall, Raphaela Rieke, Rémi Peyronnet, Geneviève Jolivet, Christoph Bode, Axel zur Hausen, Hannah E Fürniss, Ilona Bodi, Manfred Zehender, Katja E. Odening, Johannes Steinfurt, Gerlind Franke
Publikováno v:
European Heart Journal
European Heart Journal, Oxford University Press (OUP): Policy B, 2019, 40 (10), pp.842-853. ⟨10.1093/eurheartj/ehy761⟩
European Heart Journal, 40(10), 842-853. Oxford University Press
European Heart Journal, Oxford University Press (OUP): Policy B, 2019, 40 (10), pp.842-853. ⟨10.1093/eurheartj/ehy761⟩
European Heart Journal, 40(10), 842-853. Oxford University Press
AIMS Short-QT syndrome 1 (SQT1) is an inherited channelopathy with accelerated repolarization due to gain-of-function in HERG/IKr. Patients develop atrial fibrillation, ventricular tachycardia (VT), and sudden cardiac death with pronounced inter-indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11c471e972d6411e8038719e68b7b5c
https://hal.inrae.fr/hal-02619630
https://hal.inrae.fr/hal-02619630
Autor:
Gideon Koren, Ilona Bodi, Heiko Bugger, Stefanie Perez-Feliz, Gunnar Seemann, Michael Brunner, Eike M Wuelfers, Christoph Bode, Katja E. Odening, Gerlind Franke, Alessandro Castiglione, Manfred Zehender, Sylva M Glatz, Jonathan Sorge
Publikováno v:
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 21(7)
Aims Women with long QT syndrome 2 (LQT2) have a particularly high postpartal risk for lethal arrhythmias. We aimed at investigating whether oxytocin and prolactin contribute to this risk by affecting repolarization. Methods and results In female tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dadc82c0e89ad14c8acfc652e12d6d88
https://pubmed.ncbi.nlm.nih.gov/31505592
https://pubmed.ncbi.nlm.nih.gov/31505592