Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stefanie Pennavaria"'
Autor:
Anne Trefzer, Pallavi Kadam, Shu-Hung Wang, Stefanie Pennavaria, Benedikt Lober, Batuhan Akçabozan, Jan Kranich, Thomas Brocker, Naoko Nakano, Martin Irmler, Johannes Beckers, Tobias Straub, Reinhard Obst
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108748- (2021)
Summary: Exhausted immune responses to chronic diseases represent a major challenge to global health. We study CD4+ T cells in a mouse model with regulatable antigen presentation. When the cells are driven through the effector phase and are then expo
Externí odkaz:
https://doaj.org/article/591264a4d4324b9a8794cbb7e208457b
Autor:
Anne, Trefzer, Pallavi, Kadam, Shu-Hung, Wang, Stefanie, Pennavaria, Benedikt, Lober, Batuhan, Akçabozan, Jan, Kranich, Thomas, Brocker, Naoko, Nakano, Martin, Irmler, Johannes, Beckers, Tobias, Straub, Reinhard, Obst
Publikováno v:
Cell reports. 34(6)
Exhausted immune responses to chronic diseases represent a major challenge to global health. We study CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::812b4e24170229b1d637e582b0ab71b4
https://pubmed.ncbi.nlm.nih.gov/33567282
https://pubmed.ncbi.nlm.nih.gov/33567282
Autor:
Anne Trefzer, Benedikt Lober, Reinhard Obst, Shu-Hung Wang, Pallavi Kadam, Thomas Brocker, Tobias Straub, Stefanie Pennavaria, Jan Kranich, Johannes Beckers, Martin Irmler
Publikováno v:
SSRN Electronic Journal.
Exhausted immune responses to chronic diseases represent a major challenge to global health. We studied CD4+ T cells in a mouse model where presentation of their antigen can be regulated. When the cells are driven through the effector phase, but are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7a058f631561b1aa791610287c8e9a
https://doi.org/10.2139/ssrn.3549537
https://doi.org/10.2139/ssrn.3549537
Publikováno v:
The Journal of Immunology. 206:98.24-98.24
Anabolic metabolism of antigen-stimulated T cells is coordinated by mTOR which is activated by TCR and IL-2 signals. We show that mTORC1 regulates both the exit of quiescence and later divisions as Raptor-deficient T cells proceed 3x slower through e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6e88e1ce1bfea5c6c5d89573cb2ba9
https://doi.org/10.4049/jimmunol.206.supp.98.24
https://doi.org/10.4049/jimmunol.206.supp.98.24
Autor:
Pallavi Kadam, Anne Trefzer, Shu-Hung Wang, Stefanie Pennavaria, Benedikt Lober, Batuhan Akcabozan, Jan Kranich, Thomas Brocker, Naoko Nakano, Martin Irmler, Johannes Beckers, Tobias Straub, Reinhard Obst
Publikováno v:
The Journal of Immunology. 206:96.11-96.11
Exhausted immune responses to chronic diseases represent a major challenge to global health. To explore their cell fate and plasticity in exhaustion, we analyzed CD4+T cells in a mouse model with regulatable antigen presentation. When the cells are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3630d39bf9b04d925ce775eebcc0e3
https://doi.org/10.4049/jimmunol.206.supp.96.11
https://doi.org/10.4049/jimmunol.206.supp.96.11
Autor:
Batuhan Akçabozan, Shu Hung Wang, Johannes Beckers, Tobias Straub, Jan Kranich, Reinhard Obst, Naoko Nakano, Anne Trefzer, Stefanie Pennavaria, Benedikt Lober, Thomas Brocker, Martin Irmler, Pallavi Kadam
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108748-(2021)
Cell Rep. 34:108748 (2021)
Cell Rep. 34:108748 (2021)
Summary: Exhausted immune responses to chronic diseases represent a major challenge to global health. We study CD4+ T cells in a mouse model with regulatable antigen presentation. When the cells are driven through the effector phase and are then expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc889e0e10d5ba2d579fc949829d7c97
https://doi.org/10.1016/j.celrep.2021.108748
https://doi.org/10.1016/j.celrep.2021.108748
Autor:
Reinhard Obst, Anne Trefzer, Pallavi Kadam, Shu-Hung Wang, Stefanie Pennavaria, Benedikt Lober, Jan Kranich, Thomas Brocker, Martin Irmler, Johannes Beckers, Tobias Straub
Publikováno v:
The Journal of Immunology. 204:80.18-80.18
Exhausted immune responses to chronic diseases represent a major challenge to global health. We studied CD4+ T cells in a mouse model where presentation of their antigen can be regulated. When the cells are driven through the effector phase, but are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076f81dd2f7420f1298279a835dbc25f
https://doi.org/10.4049/jimmunol.204.supp.80.18
https://doi.org/10.4049/jimmunol.204.supp.80.18
Autor:
Reinhard Obst, Anne Trefzer, Stefanie Pennavaria, Shu-Hung Wang, Benedikt Lober, Ayuna Asoyan
Publikováno v:
The Journal of Immunology. 196:128.9-128.9
Chronic infections and persistent antigen presentation by tumor cells functionally impair T cells over time. To address how different kinetics and dosage of antigen presentation affect CD4+ T cells, we followed TCR transgenic T cells transferred into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69cd4dff4fa11e1aac3c8b6d4dbaac61
https://doi.org/10.4049/jimmunol.196.supp.128.9
https://doi.org/10.4049/jimmunol.196.supp.128.9