Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stefanie Mak"'
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTThe binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted on the same cell surface. Dynamic interactions between each of the antibody’s arms and its cognate target cause
Externí odkaz:
https://doaj.org/article/8423b38fd5624a7ab6c96193e44bb7da
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Bacteria can use extracellular contractile injection systems (eCISs) to inject toxic proteins into eukaryotic cells. Here, Vladimirov et al. provide evidence that the main role of eCISs in Streptomyces is not to attack other species, but to modulate
Externí odkaz:
https://doaj.org/article/75a48bb41ddf4ef08ab9b7bf5c3820cf
Publikováno v:
mAbs. 15(1)
The binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted on the same cell surface. Dynamic interactions between each of the antibody's arms and its cognate target cause the forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bd5f1d42f6d00bf8cf00647b3c823e
https://pubmed.ncbi.nlm.nih.gov/36453702
https://pubmed.ncbi.nlm.nih.gov/36453702
Autor:
Ahmed El-Boraie, Stefanie Mak, David C.F. Sealey, Katelyn. J. Kozma, Jonathan Chio, Anne Meyer-Miner
Publikováno v:
Canadian Journal of Career Development. 20:84-93
In the life sciences, many graduate students and postdoctoral fellows find it challenging to enter the non-academic workforce after completing their programs. Through experiential learning, trainees can develop the knowledge, technical skills, soft s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49eee33dafd80799be80d5ae46686f21
https://doi.org/10.53379/cjcd.2021.102
https://doi.org/10.53379/cjcd.2021.102
Extracellular contractile injection systems (eCIS) are encoded in diverse clades of bacterial species. Although closely related to contractile phage tails, these entities can inject toxic proteins into eukaryotic cells. The roles of eCIS in mediating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8641a0fc9868c075ea8398972abe75e6
https://doi.org/10.1101/2022.08.10.503483
https://doi.org/10.1101/2022.08.10.503483
Publikováno v:
The Journal of Applied Laboratory Medicine. 4:391-403
Background: Dilated cardiomyopathy (DCM) is a common cause of heart failure with high morbidity and mortality rates. The association of anti-β1 adrenergic receptor (β1AR) autoantibodies with disease progression was shown by various studies and in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274245dbfbd52314badffdba2786ca2f
https://doi.org/10.1373/jalm.2018.028225
https://doi.org/10.1373/jalm.2018.028225
Autor:
Stefanie Mak, Justin R. Nodwell
Publikováno v:
Molecular Microbiology. 106:597-613
Actinorhodin is a blue-pigmented, redox-active secondary metabolite that is produced by the bacterium Streptomyces coelicolor. Although actinorhodin has been used as a model compound for studying secondary metabolism, its biological activity is not w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::541f88ea76b8908cbf1f61a61cf89d86
https://doi.org/10.1111/mmi.13837
https://doi.org/10.1111/mmi.13837
Publikováno v:
Biochemical Journal. 474:1361-1371
Analysis of membrane proteins is still inadequately represented in diagnostics despite their importance as drug targets and biomarkers. One main reason is the difficult handling caused by their insolubility in aqueous buffer solutions. The nanodisc t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb11773c77afe85b78b0f9cca3928d2
https://doi.org/10.1042/bcj20161110
https://doi.org/10.1042/bcj20161110
Publikováno v:
Molecular Microbiology. 93:391-402
Antibiotic-producing bacteria encode antibiotic resistance genes that protect them from the biologically active molecules that they produce. The expression of these genes needs to occur in a timely manner: either in advance of or concomitantly with b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3cf817a6e9de66546475fa02a7d814f
https://doi.org/10.1111/mmi.12689
https://doi.org/10.1111/mmi.12689
Autor:
Jeannette Winter, Andrea Steiner, Maike Krause, Katharina M. Gebendorfer, Adrian Drazic, Stefanie Mak, Alexander Bepperling
Publikováno v:
The Journal of biological chemistry. 289(2)
Hypochlorous acid (HOCl) is an important component of the immune system and is produced by neutrophils to kill invading microorganisms. The transcription factor HypT is specifically activated by HOCl by methionine oxidation and protects Escherichia c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c658202f2934cf076bb7accb324b3c1b
https://pubmed.ncbi.nlm.nih.gov/24275662
https://pubmed.ncbi.nlm.nih.gov/24275662