Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Stefanie L. O'Neal"'
Autor:
Stefanie L. O’Neal, Wei Zheng
Publikováno v:
Current Environmental Health Reports. 2:315-328
Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not identical to, Parkinson's disease. Since our last review on this subject in 2004, the past decade has been a thriving period in the history of Mn research. This report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aae53a14e2b088798db7247cadf8948
https://doi.org/10.1007/s40572-015-0056-x
https://doi.org/10.1007/s40572-015-0056-x
Publikováno v:
Toxicological Sciences. 143:482-498
The brain subventricular zone (SVZ) is a source of neural precursor cells; these cells travel along the rostral migratory stream (RMS) to destination areas in the process of adult neurogenesis. Recent x-ray fluorescence (XRF) studies reveal an extens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57fff69d8bab91d82087dba6dabf467e
https://doi.org/10.1093/toxsci/kfu249
https://doi.org/10.1093/toxsci/kfu249
Publikováno v:
Acta Pharmacologica Sinica. 35:1577-1585
Para-aminosalicylic acid (PAS) is effective in the treatment of manganism-induced neurotoxicity (manganism). In this study we investigated the roles of P-glycoprotein (MDR1a) and multidrug resistance protein (MRP) in transporting PAS and its N-acetyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45c37e97ac8b05fe26cec03cc299b803
https://doi.org/10.1038/aps.2014.103
https://doi.org/10.1038/aps.2014.103
Manganese (Mn) is an essential trace element, but excess exposure leads to accumulation in biological tissues, including the brain. Chronically high Mn levels in the brain are neurotoxic and can result in a progressive, irreversible neurological diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527dee8238ad28c509cdeed437713586
https://europepmc.org/articles/PMC4278355/
https://europepmc.org/articles/PMC4278355/
Autor:
Alexander Jones, Lan Hong, Stefanie L. O’Neal, Sherleen Fu, Wei Zheng, Wendy Jiang, Linda H. Nie
Literature data indicate that bone is a major storage organ for manganese (Mn), accounting for 43% of total body Mn. However, the kinetic nature of Mn in bone, especially the half-life (t(1/2)), remained unknown. This study was designed to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6febc2041944016869f918c35f250e9
https://europepmc.org/articles/PMC4126163/
https://europepmc.org/articles/PMC4126163/