Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February–March 2021

Autor: Pinkus Tober-Lau, Tatjana Schwarz, David Hillus, Jana Spieckermann, Elisa T. Helbig, Lena J. Lippert, Charlotte Thibeault, Willi Koch, Leon Bergfeld, Daniela Niemeyer, Barbara Mühlemann, Claudia Conrad, Stefanie Kasper, Friederike Münn, Frank Kunitz, Terry C. Jones, Norbert Suttorp, Christian Drosten, Leif Erik Sander, Florian Kurth, Victor M. Corman

Publikováno v: Emerging Infectious Diseases, Vol 27, Iss 8, Pp 2169-2173 (2021)

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 vaccinated and 4/4 unvaccinated

Externí odkaz: https://doaj.org/article/689178e7809e49a2984a116167606378

A time-resolved proteomic and prognostic map of COVID-19

Autor: Vadim Demichev, Pinkus Tober-Lau, Oliver Lemke, Tatiana Nazarenko, Charlotte Thibeault, Harry Whitwell, Annika Röhl, Anja Freiwald, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Simran Kaur Aulakh, Elisa T. Helbig, Paula Stubbemann, Lena J. Lippert, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B. Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J. Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Mirja Mittermaier, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam S. Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Philipp Enghard, Aleksej Zelezniak, Archie Campbell, Caroline Hayward, David J. Porteous, Riccardo E. Marioni, Alexander Uhrig, Holger Müller-Redetzky, Heinz Zoller, Judith Löffler-Ragg, Markus A. Keller, Ivan Tancevski, John F. Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, Markus Ralser, Florian Kurth, Malte Kleinschmidt, Katrin M. Heim, Belén Millet, Lil Meyer-Arndt, Ralf H. Hübner, Tim Andermann, Jan M. Doehn, Bastian Opitz, Birgit Sawitzki, Daniel Grund, Peter Radünzel, Mariana Schürmann, Thomas Zoller, Florian Alius, Philipp Knape, Astrid Breitbart, Yaosi Li, Felix Bremer, Panagiotis Pergantis, Dirk Schürmann, Bettina Temmesfeld-Wollbrück, Daniel Wendisch, Sophia Brumhard, Sascha S. Haenel, Claudia Conrad, Philipp Georg, Kai-Uwe Eckardt, Lukas Lehner, Jan M. Kruse, Carolin Ferse, Roland Körner, Claudia Spies, Andreas Edel, Steffen Weber-Carstens, Alexander Krannich, Saskia Zvorc, Linna Li, Uwe Behrens, Sein Schmidt, Maria Rönnefarth, Chantip Dang-Heine, Robert Röhle, Emma Lieker, Lucie Kretzler, Isabelle Wirsching, Christian Wollboldt, Yinan Wu, Georg Schwanitz, David Hillus, Stefanie Kasper, Nadine Olk, Alexandra Horn, Dana Briesemeister, Denise Treue, Michael Hummel, Victor M. Corman, Christian Drosten, Christof von Kalle

Publikováno v: 794.e7
Cell Systems

COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection to severe organ damage and death. We characterized the time-dependent progression of the disease in 139 COVID-19 inpatients by measuring 86 accredited diagn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9926f617619421e736ef19e24395fb

Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1-nCoV19 and BNT162b2: a prospective cohort study

Autor: Tatjana Schwarz, David Hillus, Patricia Tscheak, Christian Drosten, Elisa T Helbig, Harald Bias, Stefanie Kasper, Florian Kurth, Norbert Suttorp, Piotr Kopankiewicz, Joachim Seybold, Andr Solarek, Leif E. Sander, Chantip Dang-Heine, Christof von Kalle, Covim, Marie Luisa Schmidt, Johanna Riege, Hana Hastor, Lena J Lippert, Pinkus Tober-Lau, Victor M. Corman, Charlotte Thibeault

Objectiveto assess reactogenicity and immunogenicity of heterologous prime-boost immunisations of ChAdOx1-nCoV19 (Vaxzevria, ChAdOx) followed by BNT162b2 (Comirnaty, BNT) compared to homologous BNT/BNT immunisation.Designprospective, observational co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::937bd1780e7eddfa2577056e9fb0f132
https://doi.org/10.1101/2021.05.19.21257334

Encapsulation in Polymeric Microparticles Improves Daptomycin Activity Against Mature Staphylococci Biofilms-a Thermal and Imaging Study

Autor: Inês Santos Ferreira, António J. Almeida, Stefanie Kasper, Judith Kikhney, Ana Bettencourt, Laura Kursawe, Annette Moter, Andrej Trampuz, Lídia Gonçalves

Publikováno v: AAPS PharmSciTech. 19(4)

Eradication of Gram-positive biofilms is a critical aspect in implant-associated infection treatment. Although antibiotic-containing particulate carriers may be a promising strategy for overcoming biofilm tolerance, the assessment of their interactio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad83510417c08b3d3702f04f58f5ce94
https://pubmed.ncbi.nlm.nih.gov/29488195

Activity of daptomycin- and vancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms

Autor: Bertrand Betrisey, António J. Almeida, Andrej Trampuz, Lídia Gonçalves, Inês Santos Ferreira, Annette Moter, Judith Kikhney, Stefanie Kasper, Ana Bettencourt

Publikováno v: International Journal of Nanomedicine

Inês Santos Ferreira,1 Ana F Bettencourt,1 Lídia MD Gonçalves,1 Stefanie Kasper,2 Bertrand Bétrisey,3 Judith Kikhney,2 Annette Moter,2 Andrej Trampuz,4 António J Almeida1 1Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Uni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f36514eadc6c55a0984275ac5ad00c
https://www.dovepress.com/activity-of-daptomycin--and-vancomycin-loaded-poly-epsilon-caprolacton-peer-reviewed-article-IJN