Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Stefanie K. Novakowski"'
Autor:
Alishah Mawji, Edmond Li, Dustin Dunsmuir, Clare Komugisha, Stefanie K. Novakowski, Matthew O. Wiens, Tagoola Abner Vesuvius, Niranjan Kissoon, J. Mark Ansermino
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
IntroductionEarly and accurate recognition of children at risk of progressing to critical illness could contribute to improved patient outcomes and resource allocation. In resource limited settings digital triage tools can support decision making and
Externí odkaz:
https://doaj.org/article/8f2976ac1dfb41b480488bf512f24f8d
Autor:
Alishah Mawji, Holly Longstaff, Jessica Trawin, Dustin Dunsmuir, Clare Komugisha, Stefanie K. Novakowski, Matthew O. Wiens, Samuel Akech, Abner Tagoola, Niranjan Kissoon, J. Mark Ansermino
Publikováno v:
PLOS Digital Health, Vol 1, Iss 8 (2022)
Data sharing has enormous potential to accelerate and improve the accuracy of research, strengthen collaborations, and restore trust in the clinical research enterprise. Nevertheless, there remains reluctancy to openly share raw data sets, in part du
Externí odkaz:
https://doaj.org/article/6221a78d452b4356828aa91c362d5f30
Autor:
Stefanie K Novakowski, Olive Kabajaasi, Mai-Lei Woo Kinshella, Yashodani Pillay, Teresa Johnson, Dustin Dunsmuir, Katija Pallot, Jessica Rigg, Nathan Kenya-Mugisha, Bernard Toliva Opar, J Mark Ansermino, Abner Tagoola, Niranjan Kissoon
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Effective triage at hospitals can improve outcomes for children globally by helping identify and prioritize care for those most at-risk of death. Paper-based pediatric triage guidelines have been developed to support frontline hea
Externí odkaz:
https://doaj.org/article/0344c53f142f4c7682e8229739464bc5
Autor:
Ahmad Asdo, Alishah Mawji, Collins Agaba, Clare Komugisha, Stefanie K Novakowski, Yashodani Pillay, Stephen Kaumu, Matthew O Wiens, Samuel Akech, Abner Tagoola, Niranjan Kissoon, J Mark Ansermino, Dustin Dunsmuir
BackgroundIn low- and middle-income countries, health workers use pulse oximeters for intermittent spot measurements of SpO2. However, the accuracy and reliability when used for spot measurements has not been determined. We evaluated the repeatabilit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::271bb503fee5186d9237ba9cda7900d5
https://doi.org/10.1101/2022.12.21.22283800
https://doi.org/10.1101/2022.12.21.22283800
Publikováno v:
Health Science Inquiry. 10
Autor:
Lih Jiin Juang, Stefanie K. Novakowski, David Gailani, Martin Haulena, Christian J. Kastrup, Nima Mazinani, Leslie M. Lavkulich, Emily N. P. Prowse
Publikováno v:
Blood advances. 4(8)
Bleeding is a common contributor to death and morbidity in animals and provides strong selective pressure for the coagulation system to optimize hemostasis for diverse environments. Although coagulation factor XII (FXII) is activated by nonbiologic s
Autor:
Stefanie K. Novakowski, Vivienne Chan, Christian J. Kastrup, Simon Law, Christa Klein-Bosgoed
Publikováno v:
Angewandte Chemie International Edition. 54:13590-13593
Transcribing exogenous RNA in eukaryotic cells requires delivering DNA to their nuclei and changing their genome. Nuclear delivery is often inefficient, limiting the potential scope of gene therapy and synthetic biology. These challenges may be overc
Publikováno v:
Journal of Molecular Biology. 426:1898-1910
The 2-oxoglutarate (2OG)/Fe2 +-dependent oxygenases (2OG oxygenases) are a large family of proteins that share a similar overall three-dimensional structure and catalyze a diverse array of oxidation reactions. The Jumonji C (JmjC)-domain-containing p
Autor:
Jörg Stetefeld, Edis Dzananovic, Ryan Howard, Soumya Deo, Sean A. McKenna, Markus Meier, Stefanie K. Novakowski, Emmanuel O. Ariyo, Oksana Marushchak, Evan P. Booy
Publikováno v:
Nucleic Acids Research
RNA Helicase associated with AU-rich element (RHAU) (DHX36) is a DEAH (Aspartic acid, Glumatic Acid, Alanine, Histidine)-box RNA helicase that can bind and unwind G4-quadruplexes in DNA and RNA. To detect novel RNA targets of RHAU, we performed an RN
Autor:
Stefanie K. Novakowski, Sean A. McKenna, Jörg Stetefeld, Shawn Xiong, Markus Meier, Natalie Okun, Evan P. Booy
Publikováno v:
Nucleic Acids Research
Human telomerase RNA (hTR) contains several guanine tracts at its 5′-end that can form a G4-quadruplex structure. Previous evidence suggests that a G4-quadruplex within this region disrupts the formation of an important structure within hTR known a