Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Stefanie J. Kirwin"'
Autor:
Erich A Heise, Lauren M Marozas, Sean A Grafton, Katelyn M Green, Stefanie J Kirwin, Patrice E Fort
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82520 (2013)
Diabetic retinopathy is the leading cause of vision loss in working-age individuals in the United States and is expected to continue growing with the increased prevalence of diabetes. Streptozotocin-induced hyperglycemia in rats is the most commonly
Externí odkaz:
https://doaj.org/article/894bf393702746189103fddf54cf8f04
Publikováno v:
Autoimmunity. 44:219-228
SJL mice represent a mouse model in which young adult females are susceptible to autoimmune disease, while age-matched males are relatively resistant. T cells primed in female SJL mice secrete cytokines associated with a Th1 phenotype. By contrast, T
Autor:
Ni Feng, Claudia Hindinger, David R. Hinton, Cornelia C. Bergmann, Kenichi C. Dowdell, Stefanie J. Kirwin, Stephen A. Stohlman
Publikováno v:
Journal of Neuroimmunology. 178:30-39
Activation of Th2 cells suppresses clinical experimental autoimmune encephalitis (EAE), demyelination and expression of genes associated with Th1-mediated inflammation. Despite both reduced central nervous system inflammation and IFN-gamma induced MH
Autor:
Patrice Fort, Stefanie J. Kirwin, Sean Grafton, Erich A. Heise, Katelyn M. Green, Lauren M. Marozas
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e82520 (2013)
PLoS ONE, Vol 8, Iss 12, p e82520 (2013)
Diabetic retinopathy is the leading cause of vision loss in working-age individuals in the United States and is expected to continue growing with the increased prevalence of diabetes. Streptozotocin-induced hyperglycemia in rats is the most commonly
Publikováno v:
Investigative ophthalmologyvisual science. 50(11)
Purpose Inflammation is thought to play a role in disease progression and vision loss in diabetic retinopathy (DR). However, the level of inflammation and the role of cytokines and growth factors in the early stages of this disease are poorly underst
Publikováno v:
Acta Ophthalmologica. 86
Purpose Complications of diabetic retinopathy, such as macular edema, appear to be generated by multiple inflammatory factors that affect the retinal microcirculation. To elucidate the cell types and mechanisms underlying diabetic complications, huma
Autor:
Cornelia C. Bergmann, David R. Hinton, Stephen A. Stohlman, Roscoe Atkinson, Margaret Burnett, Claudia Hindinger, Stefanie J. Kirwin
Publikováno v:
Journal of neuroscience research. 84(6)
Agonists of liver X receptors (LXR), members of the nuclear hormone receptor superfamily, alter secretion of proinflammatory cytokines, suggesting potential antiinflammatory effects. A synthetic LXR agonist inhibited T-cell proliferation and cytokine
Autor:
Jeffrey L. Edelman, Candice Hansen, Suzanne Kanaly, Stefanie J. Kirwin, Belinda J Cairns, Meina Ren
Publikováno v:
Investigative Opthalmology & Visual Science. 52:7654
Purpose Patients with diabetic retinopathy may experience severe vision loss due to macular edema and neovascularization secondary to vascular abnormalities. However, before these abnormalities become apparent, there are functional deficits in contra
Autor:
Claudia Hindinger, David R. Hinton, Stefanie J. Kirwin, Roscoe D. Atkinson, Margaret E. Burnett, Cornelia C. Bergmann, Stephen A. Stohlman
Publikováno v:
Journal of Neuroscience Research; Nov2006, Vol. 84 Issue 6, p1225-1234, 10p