Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Stefanie Heynck"'
Autor:
Martin Peifer, Jonathan Weiss, Martin L Sos, Mirjam Koker, Stefanie Heynck, Christian Netzer, Stefanie Fischer, Haridas Rode, Daniel Rauh, Jörg Rahnenführer, Roman K Thomas
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8919 (2010)
Despite the successful introduction of potent anti-cancer therapeutics, most of these drugs lead to only modest tumor-shrinkage or transient responses, followed by re-growth of tumors. Combining different compounds has resulted in enhanced tumor cont
Externí odkaz:
https://doaj.org/article/d43d914520a846449df82e6532342907
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
mp3 file (6.8 MB). In the inaugural edition of the Cancer Discovery podcast, Executive Editor Mark Landis talks with Matthew Meyerson about his paper, which describes the identification of the DDR2 kinase as a therapeutic target in squamous cell lung
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e5addd2d5a8ac8b634e34fdba42185
https://doi.org/10.1158/2159-8290.22529081
https://doi.org/10.1158/2159-8290.22529081
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
Supplementary Table 1 from Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db13f0f0711315c79b59f97a73ae407
https://doi.org/10.1158/2159-8290.22529072
https://doi.org/10.1158/2159-8290.22529072
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
Supplementary Figures 1-7 from Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531f85fe4c83a1a8d4a9016eb995d4c2
https://doi.org/10.1158/2159-8290.22529075.v1
https://doi.org/10.1158/2159-8290.22529075.v1
Autor:
Matthew Meyerson, Roman K. Thomas, Eric B. Haura, Kwok-Kin Wong, Nathanael S. Gray, Daniel Rauh, Jeonghee Cho, Adam J. Bass, Heidi Greulich, Wendy Winckler, Bruce E. Johnson, Pasi A. Janne, Michael J. Eck, Charles Hatton, Megan Hanna, Ming Sound Tsao, David G. Beer, Jürgen Wolf, Erich Stoelben, Hannie Sietsma, Wim Timens, Harry Groen, Joachim H. Clement, Iver Petersen, Åslaug Helland, Odd Terje Brustugun, Philippe Lorimier, Christian Brambilla, Elisabeth Brambilla, Sascha Ansén, Silvia Querings, Franziska Gabler, Frauke Leenders, Mirjam Koker, Holger Moch, Alex Soltermann, Johannes M. Heuckmann, Thomas Zander, Danila Seidel, Helga B. Salvesen, Robert C. Onofrio, Michael S. Lawrence, Jeffrey R. Simard, Martin Peifer, Stefanie Heynck, Sang Min Lim, Xianming Deng, Jianming Zhang, Wenchu Lin, Brittany A. Woods, Lear E. Brace, Wenjun Zhou, Amit Dutt, Chunxiao Xu, Alex H. Ramos, Martin L. Sos, Peter S. Hammerman
Supplementary Figure Legends 1-7 from Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5345540f2603d5198978a03ea047dd
https://doi.org/10.1158/2159-8290.22529078.v1
https://doi.org/10.1158/2159-8290.22529078.v1
Autor:
Roman K. Thomas, William Pao, Daniel Rauh, Christian Grütter, Christine M. Lovly, Jonathan Weiss, Martin Peifer, Mirjam Koker, Hyatt Balke-Want, Stefanie Heynck, Martin L. Sos, Michael Hölzel, Johannes M. Heuckmann
PDF file - 82K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2e6c8b154a248944e535dac62cc353
https://doi.org/10.1158/1078-0432.22443720
https://doi.org/10.1158/1078-0432.22443720
Autor:
Roman K. Thomas, William Pao, Daniel Rauh, Christian Grütter, Christine M. Lovly, Jonathan Weiss, Martin Peifer, Mirjam Koker, Hyatt Balke-Want, Stefanie Heynck, Martin L. Sos, Michael Hölzel, Johannes M. Heuckmann
PDF file - 2MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50874a5d582a03cee1c90d32a4e04274
https://doi.org/10.1158/1078-0432.22443717
https://doi.org/10.1158/1078-0432.22443717
Autor:
Roman K. Thomas, William Pao, Daniel Rauh, Christian Grütter, Christine M. Lovly, Jonathan Weiss, Martin Peifer, Mirjam Koker, Hyatt Balke-Want, Stefanie Heynck, Martin L. Sos, Michael Hölzel, Johannes M. Heuckmann
Purpose:EML4–ALK fusions define a subset of lung cancers that can be effectively treated with anaplastic lymphoma kinase (ALK) inhibitors. Unfortunately, the duration of response is heterogeneous and acquired resistance limits their ultimate effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1882bbf1dfc8ba00f8bba2ce513880
https://doi.org/10.1158/1078-0432.c.6519930.v1
https://doi.org/10.1158/1078-0432.c.6519930.v1
Autor:
Roman K. Thomas, Matthew Meyerson, William Pao, Hamid Kashkar, Levi A. Garraway, John D. Minna, Adi F. Gazdar, Michael Peyton, Luc Girard, Craig Mermel, Martin Peifer, Kathrin Michel, Peter Frommolt, Florian Fischer, Jonathan Weiss, Jens M. Seeger, Thomas Zander, Rosalia Rabinovsky, Stefanie Heynck, Barbara A. Weir, Mirjam Koker, Martin L. Sos
Supplementary Figure from PTEN Loss Contributes to Erlotinib Resistance in EGFR-Mutant Lung Cancer by Activation of Akt and EGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f466d89bc3b6c978e9ae0c3e673c73b
https://doi.org/10.1158/0008-5472.22379694.v1
https://doi.org/10.1158/0008-5472.22379694.v1
Autor:
Roman K. Thomas, Matthew Meyerson, William Pao, Hamid Kashkar, Levi A. Garraway, John D. Minna, Adi F. Gazdar, Michael Peyton, Luc Girard, Craig Mermel, Martin Peifer, Kathrin Michel, Peter Frommolt, Florian Fischer, Jonathan Weiss, Jens M. Seeger, Thomas Zander, Rosalia Rabinovsky, Stefanie Heynck, Barbara A. Weir, Mirjam Koker, Martin L. Sos
Clinical resistance to epidermal growth factor receptor (EGFR) inhibition in lung cancer has been linked to the emergence of the EGFR T790M resistance mutation or amplification of MET. Additional mechanisms contributing to EGFR inhibitor resistance r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200f0f591ee19ebd6e8f6906cbaf6505
https://doi.org/10.1158/0008-5472.c.6499329.v1
https://doi.org/10.1158/0008-5472.c.6499329.v1