Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stefanie Herkt"'
Autor:
Lucas Schneider, Stefanie Herkt, Lei Wang, Christine Feld, Josephine Wesely, Olga N. Kuvardina, Annekarin Meyer, Thomas Oellerich, Björn Häupl, Erhard Seifried, Halvard Bonig, Joern Lausen
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-14 (2021)
Abstract The establishment of cell type specific gene expression by transcription factors and their epigenetic cofactors is central for cell fate decisions. Protein arginine methyltransferase 6 (PRMT6) is an epigenetic regulator of gene expression ma
Externí odkaz:
https://doaj.org/article/9cf036374a43450b8c80134abeba41d3
Autor:
Annekarin Meyer, Stefanie Herkt, Heike Kunze-Schumacher, Nicole Kohrs, Julia Ringleb, Lucas Schneider, Olga N. Kuvardina, Thomas Oellerich, Björn Häupl, Andreas Krueger, Erhard Seifried, Halvard Bonig, Joern Lausen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract A network of gene regulatory factors such as transcription factors and microRNAs establish and maintain gene expression patterns during hematopoiesis. In this network, transcription factors regulate each other and are involved in regulatory
Externí odkaz:
https://doaj.org/article/08a880929fb94f77a1ebe4c4ac5a8a3a
Autor:
Nicole Kohrs, Stephan Kolodziej, Olga N Kuvardina, Julia Herglotz, Jasmin Yillah, Stefanie Herkt, Alexander Piechatzek, Gabriela Salinas Riester, Thomas Lingner, Christian Wichmann, Halvard Bonig, Erhard Seifried, Uwe Platzbecker, Hind Medyouf, Manuel Grez, Jörn Lausen
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005946 (2016)
A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemog
Externí odkaz:
https://doaj.org/article/d02eb5eaf4d447fa9f41d6ae5dba62e1
Autor:
Nadine Courtial, Christian Mücke, Stefanie Herkt, Stephan Kolodziej, Helge Hussong, Jörn Lausen
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76637 (2013)
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in
Externí odkaz:
https://doaj.org/article/d7c4d9944e3844ffbc65b59c1c3c3829
Autor:
Parimala Sonika Godavarthy, Qian Wu, Joern Lausen, Stefanie Herkt, Tina Lucas, Daniela S. Krause, Thomas Oellerich, Vivian G. Oehler, Yosif Manavski, Rahul Kumar, Djamel Aggoune, Martin Müller, Nina Hayduk, Raquel S. Pereira, Jenna M. Voutsinas, Susanne Saussele, Kuan-Ting Pan, Eva Weissenberger
Publikováno v:
Haematologica
The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6109170314835cd22389e4955a09966e
https://hdl.handle.net/21.11116/0000-0005-795A-F21.11116/0000-0005-7955-421.11116/0000-0005-7957-221.11116/0000-0005-7958-121.11116/0000-0005-7959-0
https://hdl.handle.net/21.11116/0000-0005-795A-F21.11116/0000-0005-7955-421.11116/0000-0005-7957-221.11116/0000-0005-7958-121.11116/0000-0005-7959-0
Autor:
Jasmin Yillah, Erhard Seifried, Lucas Schneider, Stefanie Herkt, H. Bönig, Nicole Kohrs, Carsten Müller-Tidow, Annekarin Meyer, Jörn Lausen, Olga N. Kuvardina
Publikováno v:
Oncotarget
Hematopoietic differentiation is controlled by key transcription factors, which regulate stem cell functions and differentiation. TAL1 is a central transcription factor for hematopoietic stem cell development in the embryo and for gene regulation dur
Autor:
Gabriela Salinas Riester, Uwe Platzbecker, Alexander Piechatzek, Manuel Grez, Christian Wichmann, Hind Medyouf, Halvard Bonig, Jörn Lausen, Jasmin Yillah, Stephan Kolodziej, Julia Herglotz, Olga N. Kuvardina, Nicole Kohrs, Thomas Lingner, Erhard Seifried, Stefanie Herkt
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005946 (2016)
PLoS Genetics
PLoS Genetics
A network of lineage-specific transcription factors and microRNAs tightly regulates differentiation of hematopoietic stem cells along the distinct lineages. Deregulation of this regulatory network contributes to impaired lineage fidelity and leukemog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8e743da73c42af550cb19bce90b66f
http://resolver.sub.uni-goettingen.de/purl?gs-1/13151
http://resolver.sub.uni-goettingen.de/purl?gs-1/13151
Autor:
Hubert Serve, Thomas Oellerich, Helge Hussong, Nicole Kohrs, Carol Stocking, Kira Behrens, Henning Urlaub, Stefanie Herkt, Julia Herglotz, Halvard Bonig, Bartosch Wojcik, Stephan Kolodziej, Jörn Lausen, Joachim Koch, Michael A. Rieger, Jasmin Corso, Ashok Kumar, Olga N. Kuvardina
Publikováno v:
Blood
The activity of antagonizing transcription factors represents a mechanistic paradigm of bidirectional lineage-fate control during hematopoiesis. At the megakaryocytic/erythroid bifurcation, the cross-antagonism of krueppel-like factor 1 (KLF1) and fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b3e198ad52e2952b9ebd4d67d61b31
https://europepmc.org/articles/PMC4463808/
https://europepmc.org/articles/PMC4463808/
Autor:
Thomas Oellerich, Joern Lausen, Stefanie Herkt, Djamel Aggoune, Vivian G. Oehler, Daniela S. Krause, Eva Weissenberger, Sonika Godavarthy, Kuan-Ting Pan, Richard A. Van Etten
Publikováno v:
Experimental Hematology. 53:S103
Autor:
Jörn Lausen, Stefanie Herkt, Stephan Kolodziej, Helge Hussong, Nadine Courtial, Christian Mücke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e76637 (2013)
PLoS ONE, Vol 8, Iss 9, p e76637 (2013)
Transcription factors play a crucial role in regulating differentiation processes during human life and are important in disease. The basic helix-loop-helix transcription factors Tal1 and Lyl1 play a major role in the regulation of gene expression in