Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Stefanie Hardt"'
Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy
Autor:
Christine Altmann, Stefanie Hardt, Caroline Fischer, Juliana Heidler, Hee-Young Lim, Annett Häussler, Boris Albuquerque, Béla Zimmer, Christine Möser, Christian Behrends, Frank Koentgen, Ilka Wittig, Mirko H.H. Schmidt, Albrecht M. Clement, Thomas Deller, Irmgard Tegeder
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 294-311 (2016)
Peripheral or central nerve injury is a frequent cause of chronic pain and the mechanisms are not fully understood. Using newly generated transgenic mice we show that progranulin overexpression in sensory neurons attenuates neuropathic pain after sci
Externí odkaz:
https://doaj.org/article/9ec104a5bf194e04889a56a8d4d4324b
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 1070-1073 (2016)
Progranulin deficiency is associated with neurodegeneration in humans and in mice. The mechanisms likely involve progranulin-promoted removal of protein waste via autophagy. We performed a deep proteomic screen of the pre-frontal cortex in aged (13
Externí odkaz:
https://doaj.org/article/9106c6eb943a4f6186518a8cc8d099f8
Autor:
M. David Brecht, Stefanie Hardt
Jedem Roadtrip wohnt ein Zauber inne. Kein Wunder, dass diese Reiseform ein echter Trend geworden ist: Mit dem Bulli, Van oder Kombi unterwegs, flexibel die Route anpassen, pausieren und schlafen, wo es schön ist - mobiles Reisen ist unabhängig, in
Autor:
Annett Wilken-Schmitz, Stefanie Hardt, Lucie Valek, Juliana Heidler, Boris Albuquerque, Michael K. E. Schäfer, Irmgard Tegeder, Christine Altmann, Ilka Wittig
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:2727-2745
Affective and cognitive processing of nociception contributes to the development of chronic pain and vice versa, pain may precipitate psychopathologic symptoms. We hypothesized a higher risk for the latter with immanent neurologic diseases and studie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c87971702a47553d0432e5913697d33c
https://doi.org/10.1016/j.bbadis.2017.07.014
https://doi.org/10.1016/j.bbadis.2017.07.014
Publikováno v:
Pain. 160(6)
Inflammation or injuries of the trigeminal nerve are often associated with persistent facial pain and its sequelae. A number of models have been described to study trigeminal pain in rodents, but the long-lasting behavioral consequences are unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d786efddb4b4e70d61c2c43b1f9aa3
https://pubmed.ncbi.nlm.nih.gov/30747909
https://pubmed.ncbi.nlm.nih.gov/30747909
Publikováno v:
Data in Brief
Data in Brief, Vol 9, Iss C, Pp 1070-1073 (2016)
Data in Brief, Vol 9, Iss C, Pp 1070-1073 (2016)
Progranulin deficiency is associated with neurodegeneration in humans and in mice. The mechanisms likely involve progranulin-promoted removal of protein waste via autophagy. We performed a deep proteomic screen of the pre-frontal cortex in aged (13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04240d936c438bab99f3080ee4e9ad7
Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy
Autor:
Stefanie Hardt, Christine Altmann, Thomas Deller, Juliana Heidler, Ilka Wittig, Hee-Young Lim, Boris Albuquerque, Caroline Fischer, Christian Behrends, Christine V. Möser, Frank Koentgen, Béla Zimmer, Irmgard Tegeder, Annett Häussler, Mirko H. H. Schmidt, Albrecht M. Clement
Publikováno v:
Neurobiology of Disease, Vol 96, Iss, Pp 294-311 (2016)
Peripheral or central nerve injury is a frequent cause of chronic pain and the mechanisms are not fully understood. Using newly generated transgenic mice we show that progranulin overexpression in sensory neurons attenuates neuropathic pain after sci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05401d11bb0783601d3f0a231b8079ec
http://www.sciencedirect.com/science/article/pii/S0969996116302248
http://www.sciencedirect.com/science/article/pii/S0969996116302248
Autor:
Stefanie Hardt, Lucie Valek, Irmgard Tegeder, Liliana Schaefer, Jinyang Zeng-Brouwers, Annett Wilken-Schmitz
Publikováno v:
Aging and Disease
Loss-of-function mutations of progranulin are associated with frontotemporal dementia in humans, and its deficiency in mice is a model for this disease but with normal life expectancy and mild cognitive decline on aging. The present study shows that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2ee593d56b05e318f19d45e0fc0331
https://pubmed.ncbi.nlm.nih.gov/30271659
https://pubmed.ncbi.nlm.nih.gov/30271659
Publikováno v:
Journal of Neuroscience Methods. 237:1-8
Background Microdialysis is an established technique for collecting small molecular weight substances (e.g. neurotransmitter and energy metabolites) from the extracellular space. The major element of microdialysis is the probe which contains a semi-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a841031cb5eca0af5852ca34a17e003c
https://doi.org/10.1016/j.jneumeth.2014.08.015
https://doi.org/10.1016/j.jneumeth.2014.08.015
Autor:
Stefanie Hardt, Jörn Lötsch, Jasper J. F. van den Bosch, Marcus J. Naumer, Patrick Pflanz, Jochen Kaiser, Stephanie Theves, Jason S. Chan
Publikováno v:
Multisensory Research. 27:225-246
The most common form of synaesthesia is grapheme–colour synaesthesia. However, rarer forms of synaesthesia also exist, such as word–gustatory and olfactory–gustatory synaesthesia, whereby a word or smell will induce a specific. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8825c4cad2f95c9810ccac279e328fd
https://doi.org/10.1163/22134808-00002451
https://doi.org/10.1163/22134808-00002451