Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Stefanie Grabrucker"'
Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model
Autor:
Florian Olde Heuvel, Najwa Ouali Alami, Oumayma Aousji, Esther Pogatzki-Zahn, Peter K. Zahn, Hanna Wilhelm, Dhruva Deshpande, Elmira Khatamsaz, Alberto Catanese, Sarah Woelfle, Michael Schön, Sanjay Jain, Stefanie Grabrucker, Albert C. Ludolph, Chiara Verpelli, Jens Michaelis, Tobias M. Boeckers, Francesco Roselli
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Background Autism Spectrum Disorders (ASD) patients experience disturbed nociception in the form of either hyposensitivity to pain or allodynia. A substantial amount of processing of somatosensory and nociceptive stimulus takes place in the
Externí odkaz:
https://doaj.org/article/bde43bf68ebe4d2c8f5a05d540104911
Autor:
Stefanie Grabrucker, Jasmin C. Haderspeck, Ann Katrin Sauer, Nadine Kittelberger, Harun Asoglu, Alireza Abaei, Volker Rasche, Michael Schön, Tobias M. Boeckers, Andreas M. Grabrucker
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2018)
A number of studies have reported changes in the hemispheric dominance in autism spectrum disorder (ASD) patients on functional, biochemical, and morphological level. Since asymmetry of the brain is also found in many vertebrates, we analyzed whether
Externí odkaz:
https://doaj.org/article/e4063373613b4fb988bfc18055fee778
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
RICH2 knockout (RICH2 KO) mice exhibit neophobia in the novel object test. To gain further insight into their anxiety-related phenotype, we subjected these mice to additional behavioral tests to elucidate whether the behavioral abnormality in these m
Externí odkaz:
https://doaj.org/article/d09b97d5dfa34c0bb06755ced49bd36b
Autor:
Francesca Pederzoli, Barbara Ruozi, Jason Duskey, Simone Hagmeyer, Ann Katrin Sauer, Stefanie Grabrucker, Romina Coelho, Natalia Oddone, Ilaria Ottonelli, Eleonora Daini, Michele Zoli, Maria Angela Vandelli, Giovanni Tosi, Andreas M. Grabrucker
Publikováno v:
Pharmaceutics, Vol 11, Iss 11, p 572 (2019)
The accumulation of amyloid β (Aβ) triggers a cascade of toxic events in Alzheimer’s disease (AD). The KLVFF peptide can interfere with Aβ aggregation. However, the peptide suffers from poor bioavailability and the inability to cross the blood
Externí odkaz:
https://doaj.org/article/1baa2c1e9c774267b60646ded6eee538
Autor:
Alice Stack, Caitriona M. Long-Smith, Yvonne M. Nolan, Denise M. O'Gorman, Stefanie Grabrucker, Erin K. Crowley
Publikováno v:
Journal of Medicinal Food. 25:924-929
Middle age is increasingly accepted as a key period during which individuals are susceptible to the effect of environmental and lifestyle factors. Emerging research indicates that dietary factors play a crucial role in brain health and cognitive func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650f58ede6030530fb545b1da1f14e7d
https://doi.org/10.1089/jmf.2020.0213
https://doi.org/10.1089/jmf.2020.0213
Autor:
Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicolo Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Moretti, Melissa Rosa, Karina Hoffmann, Jane Englsih, Aonghus Lavelle, Cora O'Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne Nolan
The gut microbiome is emerging as an important susceptibility factor in Alzheimer’s disease (AD) possibly due to the increased prevalence of pro-inflammatory genera in gut microbiota of AD participants. Microbiota-mediated changes in cognition and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9de9ac9e8dbc5de493daaf10118e3890
https://doi.org/10.21203/rs.3.rs-2272240/v1
https://doi.org/10.21203/rs.3.rs-2272240/v1
Autor:
Stefanie Grabrucker, Moira Marizzoni, Edina Silajdžić, Nicola Lopizzo, Elisa Mombelli, Sarah Nicolas, Sebastian Dohm-Hansen, Catia Scassellati, Davide Vito Moretti, Melissa Rosa, Karina Hoffmann, Jane A English, Aonghus Lavelle, Cora O’Neill, Sandrine Thuret, Annamaria Cattaneo, Yvonne M Nolan
The gut microbiome is emerging as an important susceptibility factor in Alzheimer’s disease (AD) possibly due to the increased prevalence of pro-inflammatory genera in gut microbiota of AD participants. Microbiota-mediated changes in cognition and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1351e34bc2e4240438be678eef8366cf
https://doi.org/10.1101/2022.11.04.515189
https://doi.org/10.1101/2022.11.04.515189
Autor:
Kevin Thome, Carolina Urrutia-Ruiz, Stefanie Grabrucker, Carlo Sala, Günter Ehret, Johanna Schweizer, Andreas M. Grabrucker, Tobias M. Boeckers, Michael Schön, Rong Zhang, Juergen Bockmann, Bastian Hengerer, Jessica Pagano, Chiara Verpelli
Publikováno v:
The EMBO journal 40(5), e104267 (2021). doi:10.15252/embj.2019104267
The EMBO Journal
The EMBO Journal
Impairments in social relationships and awareness are features observed in autism spectrum disorders (ASDs). However, the underlying mechanisms remain poorly understood. Shank2 is a high���confidence ASD candidate gene and localizes primarily t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a338e9ab894eff16eec4c405d9ab335c
Autor:
Tobias M. Boeckers, Carolina Urrutia-Ruiz, Silvia Cursano, Sonja Braumüller, Chiara R. Battaglia, Michael Schön, Francesco Roselli, Juergen Bockmann, Peter Radermacher, Stefanie Grabrucker, Markus Huber-Lang
Publikováno v:
Molecular Psychiatry
Older patients with severe physical trauma are at high risk of developing neuropsychiatric syndromes with global impairment of cognition, attention, and consciousness. We employed a thoracic trauma (TxT) mouse model and thoroughly analyzed age-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2674987925a2518fe0796e37a3f213
Autor:
Ilaria Ottonelli, Eleonora Daini, Maria Angela Vandelli, Giovanni Tosi, Michele Zoli, Ann Katrin Sauer, Stefanie Grabrucker, Jason T. Duskey, Romina Coelho, Simone Hagmeyer, Barbara Ruozi, Andreas M. Grabrucker, Natalia Oddone, Francesca Pederzoli
Publikováno v:
Pharmaceutics
Volume 11
Issue 11
Pharmaceutics, Vol 11, Iss 11, p 572 (2019)
Volume 11
Issue 11
Pharmaceutics, Vol 11, Iss 11, p 572 (2019)
The accumulation of amyloid &beta
(A&beta
) triggers a cascade of toxic events in Alzheimer&rsquo
s disease (AD). The KLVFF peptide can interfere with A&beta
aggregation. However, the peptide suffers from poor bioavailability and
(A&beta
) triggers a cascade of toxic events in Alzheimer&rsquo
s disease (AD). The KLVFF peptide can interfere with A&beta
aggregation. However, the peptide suffers from poor bioavailability and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f489ad2167a82793eeaa0aebd5723ad7