Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Stefanie Gier"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The pathophysiological role of Aβ42 oligomers in the onset of Alzheimer’s disease (AD) is heavily disputed, pivoting research toward investigating mixed oligomers composed of Aβ42 and Aβ40, which is more abundant but less aggregation-prone. This
Externí odkaz:
https://doaj.org/article/5cea5aed3e6347ca8ee6311f66dcadd2
Publikováno v:
mSphere, Vol 5, Iss 1 (2020)
ABSTRACT K1 represents a heterodimeric A/B toxin secreted by virus-infected Saccharomyces cerevisiae strains. In a two-staged receptor-mediated process, the ionophoric activity of K1 leads to an uncontrolled influx of protons, culminating in the brea
Externí odkaz:
https://doaj.org/article/0f31c069446848689bf4d49cf3f42a40
Autor:
Stefanie Gier, Martin Simon, Karl Nordström, Salem Khalifa, Marcel H. Schulz, Manfred J. Schmitt, Frank Breinig
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
The K1 A/B toxin secreted by virus-infected Saccharomyces cerevisiae strains kills sensitive cells via disturbance of cytoplasmic membrane functions. Despite decades of research, the mechanisms underlying K1 toxicity and immunity have not been elucid
Externí odkaz:
https://doaj.org/article/5bf5710ba7c94952ac8e6ec0799237fa
Publikováno v:
Toxins, Vol 9, Iss 11, p 345 (2017)
Killer toxin K1 is a heterodimeric protein toxin secreted by Saccharomyces cerevisiae strains infected with the M1 double-stranded RNA ‘killer’ virus. After binding to a primary receptor at the level of the cell wall, K1 interacts with its second
Externí odkaz:
https://doaj.org/article/d3e0fbace8b74322aae111f7c2de84d5
Publikováno v:
mSphere
mSphere, Vol 5, Iss 1, p e00979-19 (2020)
mSphere, Vol 5, Iss 1 (2020)
mSphere, Vol 5, Iss 1, p e00979-19 (2020)
mSphere, Vol 5, Iss 1 (2020)
The killer phenotype in the baker’s yeast Saccharomyces cerevisiae relies on two double-stranded RNA viruses that are persistently present in the cytoplasm. As they carry the same receptor populations as sensitive cells, killer yeast cells need—i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a2ca65a14172c493dfe28b58240ba1
https://doi.org/10.1128/msphere.00979-19
https://doi.org/10.1128/msphere.00979-19
Autor:
Nils Steinbrück, Saeed Ahmad Khan, Guido Kickelbick, Nasiara Karim, Dennis Becker, Sajid Khan Sadozai, Abdul Baseer, Marc Schneider, Frank Breinig, Stefanie Gier
Publikováno v:
Journal of Drug Delivery Science and Technology. 56:101574
Ketoconazole is one of the most commonly used azole drug applied in the treatment of topical fungal infections. However, due to low aqueous solubility, Ketoconazole has limited bioavailability. Therefore a higher amount of drug is required to achieve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9cf1eb24e1b8bf24c3da5e7c4288e0
https://doi.org/10.1016/j.jddst.2020.101574
https://doi.org/10.1016/j.jddst.2020.101574
Autor:
Stefanie, Gier, Martin, Simon, Karl, Nordström, Salem, Khalifa, Marcel H, Schulz, Manfred J, Schmitt, Frank, Breinig
Publikováno v:
Frontiers in Microbiology
The K1 A/B toxin secreted by virus-infected Saccharomyces cerevisiae strains kills sensitive cells via disturbance of cytoplasmic membrane functions. Despite decades of research, the mechanisms underlying K1 toxicity and immunity have not been elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ca0364df9d6764f3f2bdaa101f1502b
https://pubmed.ncbi.nlm.nih.gov/31156606
https://pubmed.ncbi.nlm.nih.gov/31156606
Publikováno v:
Frontiers in Cellular Neuroscience; 2024, p1-17, 17p
Autor:
Brettner, Felix E. B., Gier, Stefanie, Haessler, Annika, Schreiner, Jonas, Vogel-Kindgen, Sarah, Windbergs, Maike
Publikováno v:
Discover Nano; 12/21/2024, Vol. 19 Issue 1, p1-20, 20p
Publikováno v:
Toxins. Feb2023, Vol. 15 Issue 2, p96. 17p.