Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Stefanie Flohr"'
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-2 (2024)
Dr. Stefanie Flohr serves as an Associate Director at Novartis Biomedical Research in Basel, Switzerland.
Externí odkaz:
https://doaj.org/article/9182cdb45c994ea6a4c5d74e27955efa
Publikováno v:
Communications chemistry [Commun Chem] 2024 Sep 25; Vol. 7 (1), pp. 216. Date of Electronic Publication: 2024 Sep 25.
Akademický článek
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Akademický článek
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Publikováno v:
Immunological Reviews. 313:339-357
Dysregulation of the alternative complement pathway predisposes individuals to a number of diseases. It can either be evoked by genetic alterations in or by stabilizing antibodies to important pathway components and typically leads to severe diseases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47c47c18b5304aa18de9499e64ba4d5
https://doi.org/10.1111/imr.13143
https://doi.org/10.1111/imr.13143
Autor:
Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki, Karen Anderson, Aengus Mac Sweeney, Sha-Mei Liao, Upendra A. Argikar, Keith Jendza, Chun Zhang, James Powers, Daniel W. Klosowski, Maura Crowley, Toshio Kawanami, Jian Ding, Myriam April, Cornelia Forster, Michael Serrano-Wu, Michael Capparelli, Rrezarta Ramqaj, Catherine Solovay, Frederic Cumin, Thomas M. Smith, Luciana Ferrara, Wendy Lee, Debby Long, Melissa Prentiss, Andrea De Erkenez, Louis Yang, Fang Liu, Holger Sellner, Finton Sirockin, Eric Valeur, Paulus Erbel, Daniela Ostermeier, Paul Ramage, Bernd Gerhartz, Anna Schubart, Stefanie Flohr, Nathalie Gradoux, Roland Feifel, Barbara Vogg, Christian Wiesmann, Jürgen Maibaum, Jörg Eder, Richard Sedrani, Richard A. Harrison, Muneto Mogi, Bruce D. Jaffee, Christopher M. Adams
Publikováno v:
Journal of Medicinal Chemistry. 63:5697-5722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161530bd60ced781537b4b5cf97869fc
https://doi.org/10.1021/acs.jmedchem.9b01870
https://doi.org/10.1021/acs.jmedchem.9b01870
Autor:
Stefanie Flohr, Simon Rüdisser, Anna Vulpetti, Andrea De Erkenez, Stefan Steinbacher, Olivier Rogel, Laurence Kieffer, Solene Dussauge, Louis Yang, Frederic Cumin, Karen Anderson, Aengus Mac Sweeney, Edwige Lorthiois, Nils Ostermann, Ronald Newton, Viral Kansara, Sha-Mei Liao, Ulrich Hommel, Constanze Hartwieg, Upendra A. Argikar, Stefan Andreas Randl, Laura R. La Bonte, Omar Delgado, Kamal Fettis, Jürgen Maibaum, Bruce D Jaffee
Publikováno v:
Journal of Medicinal Chemistry. 60:5717-5735
The highly specific S1 serine protease factor D (FD) plays a central role in the amplification of the complement alternative pathway (AP) of the innate immune system. Genetic associations in humans have implicated AP activation in age-related macular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e242e3d44a96036addb2cb8f7ea9cefc
https://doi.org/10.1021/acs.jmedchem.7b00425
https://doi.org/10.1021/acs.jmedchem.7b00425
Autor:
Anna Vulpetti, Upendra A. Argikar, Stefanie Flohr, Aengus Mac Sweeney, Melissa Prentiss, Edwige Lorthiois, Karen Anderson, David B. Belanger, Sha-Mei Liao, Nan Ji, Christopher M. Adams, Frederic Cumin, Andrea De Erkenez, Nathalie Gradoux, Muneto Mogi, Donglei Liu, Maura Crowley, Keith Jendza, Debby Long, Nello Mainolfi, Catherine Solovay, Ann Brown, Laura R. La Bonte, Rajeshri Ganesh Karki, Omar Delgado, Powers James J, Bruce D Jaffee, Christine F. Gelin
Publikováno v:
Journal of medicinal chemistry. 62(9)
Complement factor D (FD), a highly specific S1 serine protease, plays a central role in the amplification of the alternative complement pathway (AP) of the innate immune system. Dysregulation of AP activity predisposes individuals to diverse disorder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da588cee5e7843ba124041bcbf4f4b5e
https://pubmed.ncbi.nlm.nih.gov/30995036
https://pubmed.ncbi.nlm.nih.gov/30995036
Autor:
Michael Bauch, Stefanie Flohr
Publikováno v:
Zeitschrift Interne Revision.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12f770caaac3f83c134f4debe4fd8b0f
https://doi.org/10.37307/j.1868-7814.2017.03.04
https://doi.org/10.37307/j.1868-7814.2017.03.04
Autor:
Frederic Cumin, Bernd Kinzel, Anna Vulpetti, Antonio M. Risitano, Richard A. Harrison, Kamal Fettis, Aengus Mac Sweeney, Stefan Andreas Randl, Edwige Lorthiois, Fabrice A. Kolb, Nils Ostermann, Solene Dussauge, Corinne Durand, Nicola Hughes, Bernd Gerhartz, Karen Anderson, Samuel Barbieri, Paul Erbel, Omar Delgado, Jörg Eder, Ulrich Hommel, Stefanie Flohr, Simon Rüdisser, Anna Schubart, Ty Gould, Bruce D Jaffee, Jürgen Maibaum, Julia Wagner, Sha-Mei Liao
Publikováno v:
Nature chemical biology. 12(12)
Complement is a key component of the innate immune system, recognizing pathogens and promoting their elimination. Complement component 3 (C3) is the central component of the system. Activation of C3 can be initiated by three distinct routes-the class
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2c3a47759beca17b7b3f2b775e9551
https://pubmed.ncbi.nlm.nih.gov/27857140
https://pubmed.ncbi.nlm.nih.gov/27857140