Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Stefanie Finger"'
Autor:
Karin Keppeler, Aline Pesi, Simon Lange, Johanna Helmstädter, Lea Strohm, Henning Ubbens, Marin Kuntić, Ivana Kuntić, Dominika Mihaliková, Ksenija Vujačić-Mirski, Alexandra Rosenberger, Leonie Küster, Charlotte Frank, Matthias Oelze, Stefanie Finger, Agnieszka Zakrzewska, Elena Verdu, Johannes Wild, Susanne Karbach, Philip Wenzel, Philipp Wild, David Leistner, Thomas Münzel, Andreas Daiber, Detlef Schuppan, Sebastian Steven
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103071- (2024)
Aims: We examined the cardiovascular effects of celiac disease (CeD) in a humanized mouse model, with a focus on vascular inflammation, endothelial dysfunction, and oxidative stress. Methods and results: NOD.DQ8 mice genetically predisposed to CeD we
Externí odkaz:
https://doaj.org/article/904e326b45ef4db18421f8a462304e01
Autor:
Venkata Garlapati, Michael Molitor, Thomas Michna, Gregory S. Harms, Stefanie Finger, Rebecca Jung, Jeremy Lagrange, Panagiotis Efentakis, Johannes Wild, Maike Knorr, Susanne Karbach, Sabine Wild, Ksenija Vujacic-Mirski, Thomas Münzel, Andreas Daiber, Moritz Brandt, Tommaso Gori, Hendrik Milting, Stefan Tenzer, Wolfram Ruf, Philip Wenzel
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 4 (2023)
Despite major advances in acute interventions for myocardial infarction (MI), adverse cardiac remodeling and excess fibrosis after MI causing ischemic heart failure (IHF) remain a leading cause of death worldwide. Here we identify a profibrotic coagu
Externí odkaz:
https://doaj.org/article/7166825a634c4b23b74216fd69860df6
Autor:
Jeremy Lagrange, Stefanie Finger, Sabine Kossmann, Venkata Garlapati, Wolfram Ruf, Philip Wenzel
Publikováno v:
Artery Research, Vol 26, Iss Supplement 1 (2020)
Background/Objectives: Myeloid cells are crucial for the development of vascular inflammation. Low-density lipoprotein receptor-related protein 8 (LRP8) or Apolipoprotein E receptor 2 (ApoER2), is expressed by macrophages, endothelial cells and plate
Externí odkaz:
https://doaj.org/article/f67da4c233f04b0fbd104f70338f010e
Autor:
Klytaimnistra Kiouptsi, Stefanie Finger, Venkata S. Garlapati, Maike Knorr, Moritz Brandt, Ulrich Walter, Philip Wenzel, Christoph Reinhardt
Publikováno v:
Biology Open, Vol 8, Iss 1 (2019)
The prototypic protein disulfide isomerase (PDI), encoded by the P4HB gene, has been described as a survival factor in ischemic cardiomyopathy. However, the role of protein disulfide isomerase associated 6 (PDIA6) under hypoxic conditions in the myoc
Externí odkaz:
https://doaj.org/article/9a5df5eef5fa41fda2904234bf792ca8
Autor:
Wolf-Stephan Rudi, Michael Molitor, Venkata Garlapati, Stefanie Finger, Johannes Wild, Thomas Münzel, Susanne H. Karbach, Philip Wenzel
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 396 (2021)
Aims: Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a cornerstone of drug therapy after myocardial infarction (MI) and improve left ventricular function and survival. We aimed to elucidate the impact of early treatment with the ACE in
Externí odkaz:
https://doaj.org/article/be4a671943a14cb6aad076c20cc2e89a
Autor:
Susanne H. Karbach, Tanja Schönfelder, Ines Brandão, Eivor Wilms, Nives Hörmann, Sven Jäckel, Rebecca Schüler, Stefanie Finger, Maike Knorr, Jeremy Lagrange, Moritz Brandt, Ari Waisman, Sabine Kossmann, Katrin Schäfer, Thomas Münzel, Christoph Reinhardt, Philip Wenzel
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 9, Pp n/a-n/a (2016)
Background The gut microbiome is essential for physiological host responses and development of immune functions. The impact of gut microbiota on blood pressure and systemic vascular function, processes that are determined by immune cell function, is
Externí odkaz:
https://doaj.org/article/23f3b7748f224e2cb4c4b09b7eb68219
Autor:
Michael Molitor, Maria T Bayo-Jimenez, Omar Hahad, Claudius Witzler, Stefanie Finger, Venkata S Garlapati, Sanela Rajlic, Tanja Knopp, Tabea K Bieler, Melania Aluia, Johannes Wild, Jeremy Lagrange, Recha Blessing, Steffen Rapp, Andreas Schulz, Hartmut Kleinert, Susanne Karbach, Sebastian Steven, Wolfram Ruf, Philipp Wild, Andreas Daiber, Thomas Münzel, Philip Wenzel
Publikováno v:
Cardiovascular Research.
AimsTraffic noise may play an important role in the development and deterioration of ischaemic heart disease. Thus, we sought to determine the mechanisms of cardiovascular dysfunction and inflammation induced by aircraft noise in a mouse model of myo
Autor:
Karin Keppeler, Johanna Helmstädter, Leonie Kuester, Lea Strohm, Henning Ubbens, Maria Teresa Bayo Jimenez, Marin Kuntic, Ivana Djordjevic, Stefanie Finger, Matthias Oelze, Detlef Schuppan, Philip Wenzel, Philipp Wild, Thomas Muenzel, Andreas Daiber, Sebastian Steven
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Objective: Celiac disease (CeD) is an autoimmune enteropathy triggered by dietary gluten, with a prevalence around 1%. Since many patients show heterogeneous symptoms, it is vastly underdiagnosed and yet without any treatment option besides lifelong
Autor:
Li Zhang, Felicia Dietsche, Bruno Seitaj, Liliana Rojas-Charry, Nadina Latchman, Dhanendra Tomar, Rob CI Wüst, Alexander Nickel, Katrin BM Frauenknecht, Benedikt Schoser, Sven Schumann, Michael J Schmeisser, Johannes vom Berg, Thorsten Buch, Stefanie Finger, Philip Wenzel, Christoph Maack, John W Elrod, Jan B Parys, Geert Bultynck, Axel Methner
Publikováno v:
Life science alliance, 5(10):e202201478, 1-15. Rockefeller University Press
Zhang, L, Dietsche, F, Seitaj, B, Rojas-Charry, L, Latchman, N, Tomar, D, Wüst, R C, Nickel, A, Frauenknecht, K B, Schoser, B, Schumann, S, Schmeisser, M J, Vom Berg, J, Buch, T, Finger, S, Wenzel, P, Maack, C, Elrod, J W, Parys, J B, Bultynck, G & Methner, A 2022, ' TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy ', Life science alliance, vol. 5, no. 10, e202201478, pp. 1-15 . https://doi.org/10.26508/lsa.202201478
Zhang, L, Dietsche, F, Seitaj, B, Rojas-Charry, L, Latchman, N, Tomar, D, Wüst, R C, Nickel, A, Frauenknecht, K B, Schoser, B, Schumann, S, Schmeisser, M J, Vom Berg, J, Buch, T, Finger, S, Wenzel, P, Maack, C, Elrod, J W, Parys, J B, Bultynck, G & Methner, A 2022, ' TMBIM5 loss of function alters mitochondrial matrix ion homeostasis and causes a skeletal myopathy ', Life science alliance, vol. 5, no. 10, e202201478, pp. 1-15 . https://doi.org/10.26508/lsa.202201478
Ion fluxes across the inner mitochondrial membrane control mitochondrial volume, energy production, and apoptosis. TMBIM5, a highly conserved protein with homology to putative pH-dependent ion channels, is involved in the maintenance of mitochondrial
Autor:
Stefanie Finger, Philip Wenzel, Tanja Knopp, Johannes Wild, Rebecca Schüler, Venkata Garlapati, Michael Molitor, Susanne Karbach, Wolf-Stephan Rudi, Wolfram Ruf, Maike Knorr, Thomas Münzel, Thanh Son Nguyen, Jeremy Lagrange, Sabine Kossmann
Publikováno v:
Cardiovascular Research. 117:162-177
Aims Heart failure (HF) ensuing myocardial infarction (MI) is characterized by the initiation of a systemic inflammatory response. We aimed to elucidate the impact of myelomonocytic cells and their activation by angiotensin II on vascular endothelial