Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Stefanie Donat"'
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39136 (2012)
Effective treatment of infections caused by the bacterium Staphylococcus aureus remains a worldwide challenge, in part due to the constant emergence of new strains that are resistant to antibiotics. The serine/threonine kinase PknB is of particular r
Externí odkaz:
https://doaj.org/article/7cc322a8d84541e7bbc33fb92cc30a8c
Autor:
Malgorzata Miller, Stefanie Donat, Sonja Rakette, Thilo Stehle, Thijs R H M Kouwen, Sander H Diks, Annette Dreisbach, Ewoud Reilman, Katrin Gronau, Dörte Becher, Maikel P Peppelenbosch, Jan Maarten van Dijl, Knut Ohlsen
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9057 (2010)
In eukaryotic cell types, virtually all cellular processes are under control of proline-directed kinases and especially MAP kinases. Serine/threonine kinases in general were originally considered as a eukaryote-specific enzyme family. However, recent
Externí odkaz:
https://doaj.org/article/fd65f1db7980449fbc7788397e63a8a0
Autor:
Matthias Gunzer, Andreas Beilhack, Jürgen Löffler, Knut Ohlsen, Tina Schäfer, Hermann Einsele, Mike Hasenberg, Sven Krappmann, Stefanie Donat
Publikováno v:
Virulence. 3:51-61
Non-invasive imaging techniques in microbial disease models have delivered valuable insights in the intimate pathogenhost interplay during infection. Here we describe evaluation and validation of a transgenic bioluminescence reporter strain of the hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3609643aeb85947d6725e741f859baf0
https://doi.org/10.4161/viru.3.1.18799
https://doi.org/10.4161/viru.3.1.18799
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 6, p e39136 (2012)
PLoS ONE, Vol 7, Iss 6, p e39136 (2012)
Effective treatment of infections caused by the bacterium Staphylococcus aureus remains a worldwide challenge, in part due to the constant emergence of new strains that are resistant to antibiotics. The serine/threonine kinase PknB is of particular r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e5afd873649fefebd5748307ece2e7
http://europepmc.org/articles/PMC3372466
http://europepmc.org/articles/PMC3372466
Autor:
Sander H. Diks, Knut Ohlsen, Thijs R. H. M. Kouwen, Maikel P. Peppelenbosch, Ewoud Reilman, Stefanie Donat, Doerte Becher, Jan Maarten van Dijl, Malgorzata Miller, Annette Dreisbach, Katrin Gronau, Thilo Stehle, Sonja Rakette
Publikováno v:
PLoS ONE, 5(2):9057. PUBLIC LIBRARY SCIENCE
PLoS ONE, Vol 5, Iss 2, p e9057 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 2, p e9057 (2010)
PLoS ONE
In eukaryotic cell types, virtually all cellular processes are under control of proline-directed kinases and especially MAP kinases. Serine/threonine kinases in general were originally considered as a eukaryote-specific enzyme family. However, recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22826749721b926c9899cef08561253
https://research.rug.nl/en/publications/140d6b32-5d2e-48ed-92de-c18aad7914bc
https://research.rug.nl/en/publications/140d6b32-5d2e-48ed-92de-c18aad7914bc
Publikováno v:
Chemistrybiology. 17(8)
Little is known about intracellular metabolite pools in pathogens such as Staphylococcus aureus. We have studied a particular metabolome by means of the presented LC-MS method. By investigating the central carbon metabolism which includes most of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8084a5b5043bf4bb6779159bc45ae426
https://pubmed.ncbi.nlm.nih.gov/20797611
https://pubmed.ncbi.nlm.nih.gov/20797611
Autor:
Knut Ohlsen, Stefanie Donat
Publikováno v:
International journal of medical microbiology : IJMM. 300(2-3)
In prokaryotes and eukaryotes, phosphotransfer represents a common mechanism to regulate cellular functions. Recent work revealed that modulation of cellular processes by eukaryote-like serine/threonine kinases (STKs) and phosphatases (STPs) are wide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59f8887d1ae345ec6336ad90ba38d96
https://pubmed.ncbi.nlm.nih.gov/19783479
https://pubmed.ncbi.nlm.nih.gov/19783479
Autor:
Manuel Liebeke, Stefanie Donat, Tanja Schirmeister, Karin Streker, Sonja Rakette, Knut Ohlsen, Michael Lalk, Thilo Stehle
Publikováno v:
Journal of bacteriology. 191(13)
The phosphorylation of proteins is a key regulatory mechanism in the signal transduction pathways of both prokaryotes and eukaryotes. Typically, extracellular signals are translated into cellular responses. The phosphorylation of proteins is carried
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0138ecf0f1c28024f4e701e40f8acd
https://pubmed.ncbi.nlm.nih.gov/19376851
https://pubmed.ncbi.nlm.nih.gov/19376851
Autor:
Dorthe Frees, Knut Ohlsen, Kit Boye, Lotte Jelsbak, Henrik Westh, Stefanie Donat, Hanne Ingmer, Lene Hemmingsen
Publikováno v:
International journal of medical microbiology : IJMM. 300(4)
Current models for global virulence regulation in Staphylococcus aureus are mainly based on studies performed with only a limited number of laboratory strains derived from NCTC8325. In these strains the small regulatory RNA, RNAIII, has a central rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e5732bb7a5ce1023ca2aed587bf852
https://pubmed.ncbi.nlm.nih.gov/19665927
https://pubmed.ncbi.nlm.nih.gov/19665927
Autor:
Carina A. Bäuerlein, Simone S. Riedel, Stefanie Donat, Ana-Laura Jordán-Garrote, Christian Brede, Martin Chopra, Hermann Einsele, Viktoria von Krosigk, Andreas Beilhack, Miriam Ritz, Axelle Degla, Harald Wajant
Publikováno v:
Blood. 118:1110-1110
Abstract 1110 The cytokine tumor necrosis factor-α (TNF) has pleiotropic functions both in normal physiology and disease. TNF and its relative lymphotoxin-α (LT) signal by activating two cell surface receptors TNFR1 and TNFR2. TNFR1 is expressed on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffdd56afdbeb77c5e291e84601966dbd
https://doi.org/10.1182/blood.v118.21.1110.1110
https://doi.org/10.1182/blood.v118.21.1110.1110