Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Stefanie Deubel"'
Autor:
Robert Hauffe, Michaela Rath, Mareike Schell, Katrin Ritter, Kai Kappert, Stefanie Deubel, Christiane Ott, Markus Jähnert, Wenke Jonas, Annette Schürmann, André Kleinridders
Publikováno v:
Molecular Metabolism, Vol 53, Iss , Pp 101276- (2021)
Objective: Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial dysfunction with a decreased expression of the mitochondrial chaperone HSP60. Th
Externí odkaz:
https://doaj.org/article/8e70c968a1694ff39c2a66f6cc5ab0a2
Autor:
Richard Kehm, Markus Jähnert, Stefanie Deubel, Tanina Flore, Jeannette König, Tobias Jung, Mandy Stadion, Wenke Jonas, Annette Schürmann, Tilman Grune, Annika Höhn
Publikováno v:
Redox Biology, Vol 37, Iss , Pp 101748- (2020)
Overnutrition contributes to insulin resistance, obesity and metabolic stress, initiating a loss of functional beta-cells and diabetes development. Whether these damaging effects are amplified in advanced age is barely investigated. Therefore, New Ze
Externí odkaz:
https://doaj.org/article/138edc8bf6264d7b9a4ac437f70b3559
Autor:
Raquel Fernando, Kristina Wardelmann, Stefanie Deubel, Richard Kehm, Tobias Jung, Marco Mariotti, Aphrodite Vasilaki, Vadim N. Gladyshev, André Kleinridders, Tilman Grune, José Pedro Castro
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Adipogenesis is a fundamental process of white adipose tissue function, supporting lipid storage and release, while avoiding its spillover and ectopic accumulation in tissues and organs. During aging adipogenesis is impaired and among other factors,
Externí odkaz:
https://doaj.org/article/c5adfa6ef78a4cfbab0a62d61aafe9de
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 403-409 (2017)
Cancer cells have an altered redox status, with changes in intracellular signaling pathways. The knowledge of how such processes are regulated in 3D spheroids, being well-established tumor models, is limited. To approach this question we stably trans
Externí odkaz:
https://doaj.org/article/d03bcda05ecb415f96437c9f97126256
Autor:
Cathleen John, Jana Grune, Christiane Ott, Kerstin Nowotny, Stefanie Deubel, Arne Kühne, Carola Schubert, Ulrich Kintscher, Vera Regitz-Zagrosek, Tilman Grune
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Background: Obesity is a risk factor for diseases including type 2 diabetes mellitus (T2DM) and cardiovascular disorders. Diabetes itself contributes to cardiac damage. Thus, studying cardiovascular events and establishing therapeutic intervention in
Externí odkaz:
https://doaj.org/article/d18c32be084a43c3a46daf5c3122094c
Autor:
Christiane Ott, Tobias Jung, Sarah Brix, Cathleen John, Iris R. Betz, Anna Foryst-Ludwig, Stefanie Deubel, Wolfgang M. Kuebler, Tilman Grune, Ulrich Kintscher, Jana Grune
Publikováno v:
Cells, Vol 10, Iss 4, p 805 (2021)
Cardiac remodeling and contractile dysfunction are leading causes in hypertrophy-associated heart failure (HF), increasing with a population’s rising age. A hallmark of aged and diseased hearts is the accumulation of modified proteins caused by an
Externí odkaz:
https://doaj.org/article/68900f2d9e064b7abd299ecead0b1856
Autor:
Christiane Ott, Sophia Walter, Patricia Owesny, Tobias Jung, Annika Höhn, Tim Baldensperger, Stefanie Deubel, Tilman Grune
Publikováno v:
Free Radical Biology and Medicine. 201:1
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:184-185
Autor:
Patricia Owesny, Stefanie Deubel, Niklas Hegemann, Wolfgang Kuebler, Tilman Grune, Christiane Ott
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:184
Publikováno v:
Nutrition & Diabetes, Vol 9, Iss 1, Pp 1-5 (2019)
Nutrition & Diabetes
Nutrition & Diabetes
Diet-induced hyperglycemia is described as one major contributor to the formation of advanced glycation end products (AGEs) under inflammatory conditions, crucial in type 2 diabetes progression. Previous studies have indicated high postprandial plasm