Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Stefanie Brenner"'
Autor:
Stefanie Brenner, Oliver Burk, Matthias Schwab, Svitlana Igel, Michel Eichelbaum, Ute Hofmann, M D Alscher, Heike Tegude
Publikováno v:
Clinical Pharmacology & Therapeutics. 88:685-694
The impact of thyroid dysfunction on the regulation, expression, and function of ABCB1 remains unclear. We therefore investigated ABCB1 mRNA expression and function in patients with thyroid dysfunction and studied the disposition of the ABCB1 substra
Autor:
Anna Mais, Uwe Bierbach, Ulrich Klotz, Stefanie Brenner, Peter Fritz, Dominik M. Alscher, Gereon Lauer, Horst Schweer, Hannsjörg W. Seyberth
Publikováno v:
Osteoarthritis and Cartilage. 12:469-475
Objective : The present cross sectional study was performed to test the hypothesis that in osteoarthritis (OA) of the knee severity of this disease is related to local levels of inflammatory metabolites and their corresponding enzymes. Methods : From
Autor:
Ulrich Klotz, Stefanie Brenner
Publikováno v:
European Journal of Clinical Pharmacology. 60:97-102
The MDR1-encoded P-glycoprotein (Pgp) represents the best-studied membraneous efflux pump defending the body against xenobiotics. Various polymorphisms (single nucleotide polymorphisms; SNPs) in the MDR1 gene have been identified, and a silent mutati
Autor:
Moritz Butscheid, Ulrich Klotz, Ulrich Kuhlmann, Dominik M. Alscher, Martin Kimmel, Stefanie Brenner
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 23(4)
Background. Prevention of contrast media (CM) induced nephropathy (CIN) by prophylaxis (e.g. N-acetylcysteine; NAC) is controversially discussed. Up to now, assessment of kidney function has been based on measurements of serum ' creatinine, although
Autor:
Christian Schäfer, Stefanie Brenner, Ulrich Klotz, Moritz Butscheid, Thomas E. Mürdter, Dominik M. Alscher, Monika Pischetsrieder, Matthias Frischmann, Toshimitsu Niwa
Publikováno v:
Naunyn-Schmiedeberg's archives of pharmacology. 375(6)
Advanced glycation end products (AGEs), e.g., carboxymethyllysine (CML) or imidazolone are involved in several age-related disorders. Concerning their accumulation, the importance of hepatic and renal function is controversially discussed. To test wh
Autor:
Karin Dilger, Charlotte Herrlinger, Ulrich Klotz, Ute Hofmann, Stefanie Brenner, Claudia Marx, Thomas E. Mürdter
Publikováno v:
Clinical pharmacokinetics. 42(3)
To analyse the influence of age and cytochrome P450 (CYP) 2C9 genotype on the steady-state disposition of the standard NSAID diclofenac and the new COX-2 selective inhibitor celecoxib, both of which are metabolised by the polymorphically expressed CY
Autor:
Thomas E. Mürdter, Stefanie Brenner, Frank Schönberger, Georg Heinkele, Ulrich Klotz, Ute Hofmann
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 768(2)
A simple method is described for the determination of the cyclooxygenase-2 specific inhibitor celecoxib in human serum by HPLC using the demethylated analogue as internal standard. After protein precipitation with acetonitrile, samples were extracted
Autor:
Martin Kimmel, Moritz Butscheid, Stefanie Brenner, Ulrich Kuhlmann, Ulrich Klotz, Dominik Mark Alscher
Publikováno v:
Nephrology Dialysis Transplantation; Apr2008, Vol. 23 Issue 4, p1241-1241, 1p