Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Stefanie Avril"'
Monitoring mouse papillomavirus-associated cancer development using longitudinal Pap smear screening
Autor:
Hannah M. Atkins, Aysegul Aksakal Uslu, Jingwei J. Li, Debra A. Shearer, Sarah A. Brendle, Chen Han, Michael Kozak, Paul Lopez, Deesha Nayar, Karla K. Balogh, Catherine Abendroth, Jean Copper, Keith C. Cheng, Neil D. Christensen, Yusheng Zhu, Stefanie Avril, Adam D. Burgener, Thomas T. Murooka, Jiafen Hu
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT A substantial percentage of the population remains at risk for cervical cancer due to pre-existing human papillomavirus (HPV) infections, despite prophylactic vaccines. Early diagnosis and treatment are crucial for better disease outcomes. T
Externí odkaz:
https://doaj.org/article/6e22c5056c51441a99de50ea519d0897
Autor:
Arpit Aggarwal, Sirvan Khalighi, Deepak Babu, Haojia Li, Sepideh Azarianpour-Esfahani, Germán Corredor, Pingfu Fu, Mojgan Mokhtari, Tilak Pathak, Elizabeth Thayer, Susan Modesitt, Haider Mahdi, Stefanie Avril, Anant Madabhushi
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-12 (2024)
Abstract Background The role of immune cells in collagen degradation within the tumor microenvironment (TME) is unclear. Immune cells, particularly tumor-infiltrating lymphocytes (TILs), are known to alter the extracellular matrix, affecting cancer p
Externí odkaz:
https://doaj.org/article/4d8cb787bd424bc9875541fc186dea88
Autor:
Keman Zhang, Amin Zakeri, Tyler Alban, Juan Dong, Hieu M. Ta, Ajay H. Zalavadia, Andrelie Branicky, Haoxin Zhao, Ivan Juric, Hanna Husich, Prerana B. Parthasarathy, Amit Rupani, Judy A. Drazba, Abhishek A. Chakraborty, Stanley Ching-Cheng Huang, Timothy Chan, Stefanie Avril, Li Lily Wang
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113661- (2024)
Summary: Myeloid-derived suppressor cells (MDSCs) impair antitumor immune responses. Identifying regulatory circuits during MDSC development may bring new opportunities for therapeutic interventions. We report that the V-domain suppressor of T cell a
Externí odkaz:
https://doaj.org/article/9b193a7440174faf8f405d88e86ec124
Autor:
Li Wang, Timothy Chan, Juan Dong, Hieu Ta, Keman Zhang, Tyler Alban, Abhishek Chakraborty, Stefanie Avril, Andrelie Branicky, Ajay Zalavadia, Amin Zakeri, Haoxin Zhao, Ivan Juric, Hanna Husich, Prerana Parthasarathy, Amit Rupani, Judy Drazba, Stanley Huang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d27af54e032c42259de010b8ee54dd2d
Autor:
Matthew Knarr, Rita A. Avelar, Sreeja C. Sekhar, Lily J. Kwiatkowski, Michele L. Dziubinski, Jessica McAnulty, Stephanie Skala, Stefanie Avril, Ronny Drapkin, Analisa DiFeo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
The majority of high grade serous ovarian cancers originate from fallopian tube secretory epithelial cells (FTSECs). Here the authors show that miR-181a drives oncogenic transformation in FTSECs through the cooperative inhibition of the tumor suppres
Externí odkaz:
https://doaj.org/article/0767a885d74b4bc6bb838ba3fa5b0523
Autor:
Jason Vincent, Sonya E. L. Craig, Mette L. Johansen, Jyosthna Narla, Stefanie Avril, Analisa DiFeo, Susann M. Brady-Kalnay
Publikováno v:
Diagnostics, Vol 11, Iss 2, p 181 (2021)
Background: We developed a fluorophore-conjugated peptide agent, SBK4, that detects a tumor-specific proteolyzed form of the cell adhesion molecule, PTPmu, found in the tumor microenvironment. We previously demonstrated its tissue specific distributi
Externí odkaz:
https://doaj.org/article/c5082f9692b9483f8e41c212191ca687
Autor:
Gabriele Mittermeyer, Katharina Malinowsky, Christian Beese, Heinz Höfler, Barbara Schmalfeldt, Karl-Friedrich Becker, Stefanie Avril
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77825 (2013)
Although the expression of cell signaling proteins is used as prognostic and predictive biomarker, variability of protein levels within tumors is not well studied. We assessed intratumoral heterogeneity of protein expression within primary ovarian ca
Externí odkaz:
https://doaj.org/article/8267df1f59f34539afad4514285783ac
Autor:
Katharina Malinowsky, Mithu Raychaudhuri, Theresa Buchner, Sabrina Thulke, Claudia Wolff, Heinz Höfler, Karl-Friedrich Becker, Stefanie Avril
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40285 (2012)
Proteins are used as prognostic and predictive biomarkers in breast cancer. However, the variability of protein expression within the same tumor is not well studied. The aim of this study was to assess intratumoral heterogeneity in protein expression
Externí odkaz:
https://doaj.org/article/d75c0b8963d94ce69a61194890adde34
Autor:
Huiping Liu, John S. Condeelis, Massimo Cristofanilli, Derek W. Abbott, Justin D. Lathia, Hannah L. Gilmore, Stefanie Avril, Yang Shen, Antonia Patsialou, Shivani Patel, Allison S. Harney, Yue Cao, Steven M. Chirieleison, Valery Adorno-Cruz, Elizabeth Tsui, Dhwani B. Patel, Simo Huang, Lorenzo Gerratana, Youbin Zhang, David Entenberg, Wenjing Chen, Ya-Fang Chang, Madoka Kawaguchi, Rokana Taftaf, Xia Liu
Supplementary videos (autoplay) in ppt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0261d353a9d0542996db7ab2ca73567c
https://doi.org/10.1158/2159-8290.22532701.v1
https://doi.org/10.1158/2159-8290.22532701.v1
Autor:
Huiping Liu, John S. Condeelis, Massimo Cristofanilli, Derek W. Abbott, Justin D. Lathia, Hannah L. Gilmore, Stefanie Avril, Yang Shen, Antonia Patsialou, Shivani Patel, Allison S. Harney, Yue Cao, Steven M. Chirieleison, Valery Adorno-Cruz, Elizabeth Tsui, Dhwani B. Patel, Simo Huang, Lorenzo Gerratana, Youbin Zhang, David Entenberg, Wenjing Chen, Ya-Fang Chang, Madoka Kawaguchi, Rokana Taftaf, Xia Liu
Circulating tumor cells (CTC) seed cancer metastases; however, the underlying cellular and molecular mechanisms remain unclear. CTC clusters were less frequently detected but more metastatic than single CTCs of patients with triple-negative breast ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eefab6a366a8b824296c4943d827333
https://doi.org/10.1158/2159-8290.c.6546805.v1
https://doi.org/10.1158/2159-8290.c.6546805.v1