Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Stefanie, Schlager"'
Autor:
Madeleine Goeritzer, Stefanie Schlager, Katharina B. Kuentzel, Nemanja Vujić, Melanie Korbelius, Silvia Rainer, Dagmar Kolb, Marion Mussbacher, Manuel Salzmann, Waltraud C. Schrottmaier, Alice Assinger, Axel Schlagenhauf, Corina T. Madreiter-Sokolowski, Sandra Blass, Thomas O. Eichmann, Wolfgang F. Graier, Dagmar Kratky
Publikováno v:
Cells, Vol 11, Iss 5, p 850 (2022)
According to genome-wide RNA sequencing data from human and mouse platelets, adipose triglyceride lipase (ATGL), the main lipase catalyzing triglyceride (TG) hydrolysis in cytosolic lipid droplets (LD) at neutral pH, is expressed in platelets. Curren
Externí odkaz:
https://doaj.org/article/a161f0b541984c52ab20b2cc71855bf1
Autor:
Nina Kerres, Steffen Steurer, Stefanie Schlager, Gerd Bader, Helmut Berger, Maureen Caligiuri, Christian Dank, John R. Engen, Peter Ettmayer, Bernhard Fischerauer, Gerlinde Flotzinger, Daniel Gerlach, Thomas Gerstberger, Teresa Gmaschitz, Peter Greb, Bingsong Han, Elizabeth Heyes, Roxana E. Iacob, Dirk Kessler, Heike Kölle, Lyne Lamarre, David R. Lancia, Simon Lucas, Moriz Mayer, Katharina Mayr, Nikolai Mischerikow, Katja Mück, Christoph Peinsipp, Oliver Petermann, Ulrich Reiser, Dorothea Rudolph, Klaus Rumpel, Carina Salomon, Dirk Scharn, Renate Schnitzer, Andreas Schrenk, Norbert Schweifer, Diane Thompson, Elisabeth Traxler, Roland Varecka, Tilman Voss, Alexander Weiss-Puxbaum, Sandra Winkler, Xiaozhang Zheng, Andreas Zoephel, Norbert Kraut, Darryl McConnell, Mark Pearson, Manfred Koegl
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2860-2875 (2017)
The transcription factor BCL6 is a known driver of oncogenesis in lymphoid malignancies, including diffuse large B cell lymphoma (DLBCL). Disruption of its interaction with transcriptional repressors interferes with the oncogenic effects of BCL6. We
Externí odkaz:
https://doaj.org/article/43ac770ae3294c078849cf3143253f8a
Autor:
Andrea Dichlberger, Stefanie Schlager, Katariina Maaninka, Wolfgang J. Schneider, Petri T. Kovanen
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 12, Pp 2471-2478 (2014)
Human mast cells (MCs) contain TG-rich cytoplasmic lipid droplets (LDs) with high arachidonic acid (AA) content. Here, we investigated the functional role of adipose TG lipase (ATGL) in TG hydrolysis and the ensuing release of AA as substrate for eic
Externí odkaz:
https://doaj.org/article/029ff897234f4089867fd53e5596265f
Autor:
Madeleine Goeritzer, Stefanie Schlager, Branislav Radovic, Corina T. Madreiter, Silvia Rainer, Gwynneth Thomas, Caleb C. Lord, Jessica Sacks, Amanda L. Brown, Nemanja Vujic, Sascha Obrowsky, Vinay Sachdev, Dagmar Kolb, Prakash G. Chandak, Wolfgang F. Graier, Wolfgang Sattler, J. Mark Brown, Dagmar Kratky
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 12, Pp 2562-2575 (2014)
Cellular TG stores are efficiently hydrolyzed by adipose TG lipase (ATGL). Its coactivator comparative gene identification-58 (CGI-58) strongly increases ATGL-mediated TG catabolism in cell culture experiments. To investigate the consequences of CGI-
Externí odkaz:
https://doaj.org/article/6c08cfbd5a4e4241921cb0bb76dbc68b
Autor:
Sascha Obrowsky, Prakash G. Chandak, Jay V. Patankar, Silvia Povoden, Stefanie Schlager, Erin E. Kershaw, Juliane G. Bogner-Strauss, Gerald Hoefler, Sanja Levak-Frank, Dagmar Kratky
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 2, Pp 425-435 (2013)
Adipose triglyceride lipase (ATGL) is the rate-limiting enzyme mediating triglyceride (TG) hydrolysis. The lack of ATGL results in TG accumulation in multiple tissues, underscoring the critical role of ATGL in maintaining lipid homeostasis. Recent ev
Externí odkaz:
https://doaj.org/article/89c9b262ad324158ae8a8b4067e495ba
Autor:
Nemanja Vujic, Jess Porter Abate, Stefanie Schlager, Tovo David, Dagmar Kratky, Suneil K Koliwad
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156364 (2016)
The final step of triacylglycerol synthesis is catalyzed by acyl-CoA:diacylglycerol acyltransferases (DGATs). We have previously shown that ApoE-/-Dgat1-/- mice are protected from developing atherosclerosis in association with reduced foam cell forma
Externí odkaz:
https://doaj.org/article/3f1c8d1d57104afdb33ad394e8e64c5e
Autor:
Andrea Dichlberger, Stefanie Schlager, Jani Lappalainen, Reijo Käkelä, Katarina Hattula, Sarah J. Butcher, Wolfgang J. Schneider, Petri T. Kovanen
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 12, Pp 2198-2208 (2011)
Lipid droplets, also called lipid bodies (LB) in inflammatory cells, are important cytoplasmic organelles. However, little is known about the molecular characteristics and functions of LBs in human mast cells (MC). Here, we have analyzed the genesis
Externí odkaz:
https://doaj.org/article/3d6d516eec4445d3b922f1ec3f806ce0
Autor:
Niyazi Serdar Sariciftci, Stefanie Schlager, Anita Fuchsbauer, Marianne Haberbauer, Helmut Neugebauer
Publikováno v:
Journal of Materials Chemistry A. 5:2429-2443
Carbon dioxide has evolved from being considered as a greenhouse gas to a valuable carbon feedstock for the generation of artificial fuels and valuable chemicals. In this work, we review the biocatalytic approaches towards CO2 conversion into chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47d7eec61985c1b2c19a0c1b6e753574
https://doi.org/10.1039/c6ta07571a
https://doi.org/10.1039/c6ta07571a
Autor:
Daniel Gerlach, Sabine Olt, Stefanie Schlager, Sophia M Blake, Anja Ebert, Manfred Koegl, Oliver Bergner, Johannes Wachter, Anna K. Traunbauer, Mark Pearson, Norbert Kraut, Johannes Zuber, Christoph Albrecht, Barbara Drobits, Norbert Schweifer, Martina Minnich, Vittoria Zinzalla, Francesca Trapani, Matthias Hinterndorfer, Tilman Voss, Julian Jude, Darryl B. McConnell, Carina Salomon
Publikováno v:
Oncotarget
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphomas worldwide and is characterized by a high diversity of genetic and molecular alterations. Chromosomal translocations and mutations leading to deregulated expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e39bab60623b240ea21f21b00de8086
https://pubmed.ncbi.nlm.nih.gov/32180900
https://pubmed.ncbi.nlm.nih.gov/32180900
Autor:
Dagmar Kolb, Christoph Magnes, Clemens Diwoky, Tamara Tomin, Ruth Birner-Gruenberger, Wolfgang F. Graier, Stefanie Schlager, Saša Frank, Madeleine Goeritzer, Branislav Radovic, Matthias Schittmayer, Nemanja Vujic, Martin Wegscheider, Ernst Steyrer, Julia Reindl, Melanie Korbelius, Christina Leopold, Dagmar Kratky, Jay V. Patankar, Tobias Madl, Lukas N. Groschner, Hong Du
Publikováno v:
Diabetologia
Diabetologia 59, 1743-1752 (2016)
Diabetologia 59, 1743-1752 (2016)
Lysosomal acid lipase (LAL) hydrolyses cholesteryl esters and triacylglycerols (TG) within lysosomes to mobilise NEFA and cholesterol. Since LAL-deficient (Lal -/- ) mice suffer from progressive loss of adipose tissue and severe accumulation of lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6835daf0a25ebf7ce3af110e0560e9b7
http://europepmc.org/articles/PMC4930475
http://europepmc.org/articles/PMC4930475