Výsledky vyhledávání - "Stefanie, Jörg"

Akademický článek

Impact of combined sodium chloride and saturated long-chain fatty acid challenge on the differentiation of T helper cells in neuroinflammation

Autor: Anna Hammer, Anne Schliep, Stefanie Jörg, Aiden Haghikia, Ralf Gold, Markus Kleinewietfeld, Dominik N. Müller, Ralf A. Linker

Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-9 (2017)

Abstract Background There has been a marked increase in the incidence of autoimmune diseases like multiple sclerosis (MS) in the last decades which is most likely driven by a change in environmental factors. Here, growing evidence suggests that ingre

Externí odkaz: https://doaj.org/article/94c7adf7e5824c2f9f47788971bad708

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Akademický článek

Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells

Autor: Anna Hammer, Anne Waschbisch, Ilka Knippertz, Elisabeth Zinser, Johannes Berg, Stefanie Jörg, Kristina Kuhbandner, Christina David, Jingbo Pi, Antonios Bayas, De-Hyung Lee, Aiden Haghikia, Ralf Gold, Alexander Steinkasserer, Ralf A. Linker

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

To date, the intracellular signaling pathways involved in dendritic cell (DC) function are poorly understood. The antioxidative transcription factor nuclear factor (erythroid-derived 2)-like 2 (Nrf2) has been shown to affect maturation, function, and

Externí odkaz: https://doaj.org/article/39595151b62e44458de4f9c1455f67cc

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Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine

Publikováno v: Immunity. 43(4):817-829

SummaryGrowing empirical evidence suggests that nutrition and bacterial metabolites might impact the systemic immune response in the context of disease and autoimmunity. We report that long-chain fatty acids (LCFAs) enhanced differentiation and proli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea8c7f3ccc7e1c3a92bac89af9eb58b

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Probabilistic Forecasts of Snow Water Equivalent and Runoff in Mountainous Areas*

Autor: Stefanie Jörg-Hess, Nena Griessinger, Massimiliano Zappa

Publikováno v: Journal of Hydrometeorology. 16:2169-2186

Good initial states can improve the skill of hydrological ensemble predictions. In mountainous regions such as Switzerland, snow is an important component of the hydrological system. Including estimates of snow cover in hydrological models is of grea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92a1ec265c1c8d02fa551d2798c92002
https://doi.org/10.1175/jhm-d-14-0193.1

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Nimodipine fosters remyelination in a mouse model of multiple sclerosis and induces microglia-specific apoptosis

Autor: Marie Wunsch, Johannes W. Hell, Erhard Wischmeyer, Oleg Volovitch, Stefanie Kuerten, Andrea Schampel, Tobias Koeniger, Claus Jürgen Scholz, Ralf A. Linker, Süleyman Ergün, Stefanie Jörg

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 114, iss 16

Despite continuous interest in multiple sclerosis (MS) research, there is still a lack of neuroprotective strategies, because the main focus has remained on modulating the immune response. Here we performed in-depth analysis of neurodegeneration in e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b9dbd9c29102d98e4bbe45e349cf61
https://escholarship.org/uc/item/3h96d0jv

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Testosterone Differentially Affects T Cells and Neurons in Murine and Human Models of Neuroinflammation and Neurodegeneration

Autor: Stefanie Jörg, Barbara Gisevius, Megan G. Massa, Johannes Berg, Christina David, Ralf A. Linker, Ralf Gold, Aiden Haghikia, Sarah Hirschberg

Publikováno v: The American journal of pathology. 187(7)

The high female-to-male sex ratio of multiple sclerosis (MS) prevalence has continuously confounded researchers, especially in light of male patients' accelerated disease course at later stages of MS. Although multiple studies have concentrated on es

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35736dace32c603cc6fe399102a36b2
https://pubmed.ncbi.nlm.nih.gov/28634006

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Pivotal role of choline metabolites in remyelination

Publikováno v: Brain. 138:398-413

Neuroprotective approaches for central nervous system regeneration have not been successful in clinical practice so far and compounds that enhance remyelination are still not available for patients with multiple sclerosis. The objective of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af1d490cd5f7a0275c5d9e2e1abb179d
https://doi.org/10.1093/brain/awu358

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The benefit of climatological and calibrated reforecast data for simulating hydrological droughts in Switzerland

Autor: Felix Fundel, Stefanie Jörg-Hess, Silja B. Kempf, Massimiliano Zappa

Publikováno v: Meteorological Applications. 22:444-458

Streamflow droughts are characterized by reduced runoff and can cause significant damage to nature and society. Forecasts of streamflow droughts could improve risk management and preparedness. How the quality of the meteorological forcing of a hydrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ea33af7f188cf70ec23d3eb8d9e892d0
https://doi.org/10.1002/met.1474

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Homogenisation of a gridded snow water equivalent climatology for Alpine terrain: methodology and applications

Autor: Felix Fundel, Massimiliano Zappa, Tobias Jonas, Stefanie Jörg-Hess

Publikováno v: The Cryosphere, Vol 8, Iss 2, Pp 471-485 (2014)

Gridded snow water equivalent (SWE) data sets are valuable for estimating the snow water resources and verify different model systems, e.g. hydrological, land surface or atmospheric models. However, changing data availability represents a considerabl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40823ea2d61b2b802c814cc2db390d9f
https://doi.org/10.5194/tc-8-471-2014

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Monthly hydrometeorological ensemble prediction of streamflow droughts and corresponding drought indices

Autor: Felix Fundel, Stefanie Jörg-Hess, Massimiliano Zappa

Publikováno v: Hydrology and Earth System Sciences, 17 (1)
Hydrology and Earth System Sciences, Vol 17, Iss 1, Pp 395-407 (2013)
Hydrology and Earth System Sciences

Streamflow droughts, characterized by low runoff as consequence of a drought event, affect numerous aspects of life. Economic sectors that are impacted by low streamflow are, e.g., power production, agriculture, tourism, water quality management and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::765fa60c749cca5a878015579f5fe483
https://doi.org/10.5194/hess-17-395-2013

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