Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Stefanie, Friedrich"'
Autor:
A. M. Mahedi Hasan, Paolo Cremaschi, Daniel Wetterskog, Anuradha Jayaram, Stephen Q. Wong, Scott Williams, Anupama Pasam, Anna Trigos, Blanca Trujillo, Emily Grist, Stefanie Friedrich, Osvaldas Vainauskas, Marina Parry, Mazlina Ismail, Wout Devlies, Anna Wingate, Mark Linch, Cristina Naceur-Lombardelli, PEACE consortium, Charles Swanton, Mariam Jamal-Hanjani, Stefano Lise, Shahneen Sandhu, Gerhardt Attard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Despite initial responses to hormone treatment, metastatic prostate cancer invariably evolves to a lethal state. To characterize the intra-patient evolutionary relationships of metastases that evade treatment, we perform genome-wide copy num
Externí odkaz:
https://doaj.org/article/15b82c9f94984634bd2b43be9ad37a9e
Autor:
Stefanie Friedrich, Felix Busch, Martin Jonczyk, Gero Wieners, Georg Böning, Willie Magnus Lüdemann, Aymen Meddeb, Federico Collettini, Bernhard Gebauer
Publikováno v:
Journal of Contemporary Brachytherapy, Vol 15, Iss 1, Pp 15-26 (2023)
Externí odkaz:
https://doaj.org/article/aa60b5128eaf40dd84bcbcfb8e8ea04a
Autor:
Maja Marklund, Niklas Schultz, Stefanie Friedrich, Emelie Berglund, Firas Tarish, Anna Tanoglidi, Yao Liu, Ludvig Bergenstråhle, Andrew Erickson, Thomas Helleday, Alastair D. Lamb, Erik Sonnhammer, Joakim Lundeberg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Spatial heterogeneity in prostate cancer can contribute to its resistance to androgen deprivation therapy (ADT). Here, the authors analyse prostate cancer samples before and after ADT using Spatial Transcriptomics, and find heterogeneous pre-treatmen
Externí odkaz:
https://doaj.org/article/d1623c1686dc4be4860f28f2dd32be90
Autor:
Emily Grist, Stefanie Friedrich, Christopher Brawley, Larissa Mendes, Marina Parry, Adnan Ali, Aine Haran, Alex Hoyle, Claire Gilson, Sharanpreet Lall, Leila Zakka, Carla Bautista, Alex Landless, Karolina Nowakowska, Anna Wingate, Daniel Wetterskog, A. M. Mahedi Hasan, Nafisah B. Akato, Malissa Richmond, Sofeya Ishaq, Nik Matthews, Anis A. Hamid, Christopher J. Sweeney, Matthew R. Sydes, Daniel M. Berney, Stefano Lise, STAMPEDE investigators, Mahesh K. B. Parmar, Noel W. Clarke, Nicholas D. James, Paolo Cremaschi, Louise C. Brown, Gerhardt Attard
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-15 (2022)
Abstract Background Genomic copy number alterations commonly occur in prostate cancer and are one measure of genomic instability. The clinical implication of copy number change in advanced prostate cancer, which defines a wide spectrum of disease fro
Externí odkaz:
https://doaj.org/article/506e0f56118040028d430cc8873797f0
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Fusion transcripts are involved in tumourigenesis and play a crucial role in tumour heterogeneity, tumour evolution and cancer treatment resistance. However, fusion transcripts have not been studied at high spatial resolution in t
Externí odkaz:
https://doaj.org/article/c2f8b8c1b2124f7c84a8e83b8655ae32
Publikováno v:
BMC Medical Genomics, Vol 13, Iss 1, Pp 1-12 (2020)
Abstract Background The majority of copy number callers requires high read coverage data that is often achieved with elevated material input, which increases the heterogeneity of tissue samples. However, to gain insights into smaller areas within a t
Externí odkaz:
https://doaj.org/article/82f14192d2064375a1703b3338567e35
Autor:
Emelie Berglund, Jonas Maaskola, Niklas Schultz, Stefanie Friedrich, Maja Marklund, Joseph Bergenstråhle, Firas Tarish, Anna Tanoglidi, Sanja Vickovic, Ludvig Larsson, Fredrik Salmén, Christoph Ogris, Karolina Wallenborg, Jens Lagergren, Patrik Ståhl, Erik Sonnhammer, Thomas Helleday, Joakim Lundeberg
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Heterogeneity within tumors presents a challenge to cancer treatment. Here, the authors investigate transcriptional heterogeneity in prostate cancer, examining expression profiles of different tissue components and highlighting expression gradients i
Externí odkaz:
https://doaj.org/article/df809a2fbbdf48cfa7dfe5406664fb32
Autor:
Dennis Kannenkeril, Joanna M. Harazny, Agnes Bosch, Christian Ott, Georg Michelson, Roland E. Schmieder, Stefanie Friedrich
Publikováno v:
Blood Pressure, Vol 27, Iss 2, Pp 82-87 (2018)
Purpose: Retinal microcirculation represents an easily accessible, non-invasive, in-vivo possibility to assess early microvascular changes. In addition to the assessment of functional (e.g. retinal capillary flow, RCF) and retinal arteriolar structur
Externí odkaz:
https://doaj.org/article/fd76f9215d1440e9ab6175607267b4d6
Autor:
Agnes J. Bosch, Joanna M. Harazny, Iris Kistner, Stefanie Friedrich, Joanna Wojtkiewicz, Roland E. Schmieder
Publikováno v:
BMC Cardiovascular Disorders, Vol 17, Iss 1, Pp 1-11 (2017)
Abstract Background Microvascular rarefaction influences peripheral vascular resistance, perfusion and metabolism by affecting blood pressure and flow pattern. In hypertension microvascular rarefaction has been described in experimental animal studie
Externí odkaz:
https://doaj.org/article/53d288e1f3df466f9c2f2389bb10c740
Autor:
Stefanie Friedrich, Susanne Lüders, Stephanie Gabriele Werner, Anne-Marie Glimm, Gerd-Rüdiger Burmester, Gabriela Riemekasten, Marina Backhaus, Sarah Ohrndorf
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-13 (2017)
Abstract Background Utilising fluorescence optical imaging (FOI), the distribution of an intravenously applied colouring agent indocyanine green (ICG) can be analysed with the potential to identify malperfusion by little to no tissue enhancement. Sys
Externí odkaz:
https://doaj.org/article/ee87bb2a569743d5b7ec56b0c585ee4e